- RecruitingPHASE2
Effects of Blocking TSLP on Airway Inflammation and the Epithelial Immune-response to Exacerbation Triggers in Patients With COPD
This study is looking at a new medicine called tezepelumab for people with COPD. It aims to see if this medicine can help reduce inflammation in the airways and prevent flare-ups of their condition.
For: COPD · COPD Exacerbation · COPD BronchitisDenmark · United Kingdom - Active not recruitingPHASE3
A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab
This study looks at how a new medicine, tezepelumab, helps adults in the UK with a blocked nose and other problems caused by long-lasting sinus issues and nasal polyps. It checks if their symptoms improve over 24 weeks of treatment.
For: Chronic Rhinosinusitis With Nasal PolypsUnited States · Bulgaria · Canada - RecruitingPHASE3
A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma
This study looks at a new medicine called Tezepelumab for children aged 5-11 with severe asthma. It compares the medicine to a dummy treatment (placebo) to see if it helps reduce asthma attacks and is safe for children.
For: AsthmaUnited States · Argentina · Brazil - Active not recruitingPHASE2
Explore the Efficacy and Mechanism of Action of Tezepelumab in Eosinophilic Granulomatosis With Polyangiitis
This study looks at a new drug, tezepelumab, for a rare condition called EGPA. It aims to see if the drug works and how it affects the body in adults with EGPA, helping them reduce steroid use.
For: EGPA - Eosinophilic Granulomatosis With PolyangiitisUnited Kingdom - Active not recruitingPHASE3
Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma.
This study looks at how well a new asthma medicine, tezepelumab, works to control severe asthma while patients try to reduce their regular asthma inhaler use. It aims to see if patients can stay well on less medicine.
For: Severe AsthmaUnited States · Argentina · Belgium - RecruitingNA
Physical Activity Promotion and Clinical Remission in Severe Asthma
This study looks at whether adding a special exercise programme to standard severe asthma treatment (tezepelumab) helps more adults achieve remission. It aims to see if being more active can improve health outcomes for people with severe asthma.
For: Severe AsthmaUnited Kingdom - Active not recruitingPHASE3
Efficacy and Safety of Tezepelumab in Patients With Eosinophilic Esophagitis
This study is looking at a new medicine called Tezepelumab for people aged 12-80 with Eosinophilic Oesophagitis (EoE). It aims to see if regular injections help improve symptoms and is safe, compared to a dummy treatment.
For: Eosinophilic EsophagitisUnited States · Australia · Austria - RecruitingPHASE3
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
This study is testing a new medicine, tezepelumab, for adults with moderate to very severe COPD. It wants to see if the medicine helps improve their breathing and overall health, and if it's safe to use.
For: Chronic Obstructive Pulmonary Disease (COPD)United States · Brazil · Canada