- Active not recruitingPHASE1
A Phase 1b Trial to Evaluate Safety of MB097 in Combination With Pembrolizumab in Melanoma Patients
This study looks at a new drug, MB097, combined with another treatment, Pembrolizumab, for people with melanoma that hasn't responded to previous therapy. Researchers want to see if this combination is safe and how well people tolerate it.
For: MelanomaFrance · Italy · Spain - RecruitingPHASE4
Staphylococcus Aureus Network Adaptive Platform Trial
The SNAP trial is studying different treatments for a serious blood infection called Staphylococcus aureus (S. aureus) to find out which ones work best. It aims to reduce serious illness and death by testing various medicines and approaches.
For: Staphylococcus Aureus BacteremiaUnited States · Australia · Canada - AuthorisedTherapeutic use (Phase IV)
Defining Antibiotic Levels in Intensive care patients (DALI-2) protocol - A multi-national pharmacokinetic/pharmacodynamic cohort study to determine whether contemporary antibiotic dosing for critically ill patients achieves therapeutic exposures.
This study looks at how well antibiotics work in very sick patients. Researchers want to make sure these important medicines reach the right levels in the body to fight serious infections effectively and safely. It's about getting the dose just right.
For: Serious infections in critically ill patients treated with antibioticsFrance - AuthorisedTherapeutic exploratory (Phase II)
A Multicentre, Open-Label Study Evaluating the Safety, Tolerability and Efficacy of MaaT013 in Ruxolitinib-Refractory or Intolerant Paediatric and Adolescent participants with Gastrointestinal Acute Graft-versus-Host Disease
This study looks at a new treatment called MaaT013 for children and teenagers with a gut condition called Graft-versus-Host Disease (GvHD). We want to see how safe and effective it is, especially when other treatments haven't worked or caused problems.
For: Gastrointestinal Acute Graft-versus-Host Disease (GI-aGvHD)Netherlands · Italy · France - AuthorisedTherapeutic use (Phase IV)
Phase IV, randomized, open label, parallel groups clinical trial for evaluating the early Stop of antibiotic Treatment in high-risk febrile neutropenic Oncohaematological Paediatric patients (e-STOP 2)
This study looks into safely stopping antibiotics early for children with cancer who get fevers due to low white blood cells. It compares two groups to see if ending antibiotic treatment sooner is just as safe as longer treatment for these children.
For: Infectious diseasesSpain