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IONA Longitudinal Cohort Study

The IONA study aims to understand how diseases that cause memory and thinking problems, like dementia and Alzheimer's disease, develop. This is becoming increasingly important as more people in Scotland are affected. Researchers are gathering information over several years about people's memory and thinking skills, lifestyle choices, and health risks like hearing loss and obesity. They also look at genetics and biological markers. The study's main goals are to create a detailed picture of the Scottish population, use this data to understand how these diseases progress, and identify groups who might experience the disease differently. Participants can also choose to be informed about other future research studies.

At a glance

Status
Recruiting
Sponsor
Brain Health Scotland Life Sciences Ltd
Enrolment target
10,000
Start
21 Dec 2023
Estimated completion
21 Dec 2033

What is this study about?

The IONA Longitudinal Cohort Study is a very important project happening in Scotland. It's designed to help us learn more about conditions that affect our memory and thinking, such as Alzheimer's disease and other types of dementia. As more people in Scotland live with or are affected by these conditions, understanding them better becomes crucial.

In this study, researchers are looking at many different aspects of people's health over several years. This includes how their memory and thinking abilities change, what their lifestyles are like, and if they have any health factors that might increase their risk of dementia, such as hearing problems or being overweight. They're also examining genetics and certain biological markers in the body. By collecting all this information, the study aims to build a detailed picture of the Scottish population aged 50 and over. This will help them understand how these conditions develop and progress, and identify if certain groups of people experience the disease in different ways.

Ultimately, the knowledge gained from the IONA study could be vital. It will help scientists around the world develop more accurate ways to diagnose these conditions earlier and create new, more effective treatments. The study also allows people to say if they'd like to hear about other research projects they might be interested in joining in the future.

Key takeaways

  • The IONA study is a long-term research project in Scotland.
  • It aims to understand how dementia and Alzheimer's disease develop.
  • Participants provide information on memory, lifestyle, genetics, and health.
  • The goal is to help develop better diagnoses and treatments for dementia.
  • Participation is voluntary and you can withdraw at any time.

Who may be eligible?

To be able to take part in this study, you need to be at least 50 years old and currently living in Scotland. You should be able to read and write, and have had at least seven years of formal education, like school or college.

It's important that you can understand the study information and decide for yourself if you want to take part (this is called giving "informed consent"). You also need to be able to speak English well enough to complete memory and thinking tests. Another requirement is to have a "study partner" – this is someone aged 18 or older who knows you well and can provide extra information about you if needed.

Quick self-check
  • Are you at least 50 years old?
  • Do you currently live in Scotland?
  • Can you read and write, and did you have at least 7 years of schooling?
  • Can you understand information and agree to take part?
  • Do you have a study partner (aged 18+) who knows you well?
  • Can you speak English well enough for memory tests?

This is a guide only — the research team will confirm whether you can take part.

What does participation involve?

The study involves gathering information over a number of years. You will likely have assessments to check your memory and thinking skills, and researchers will collect details about your lifestyle, health, and any risk factors for dementia. This might include questionnaires, physical measurements, and possibly samples for genetic and biological marker analysis. The study does not involve taking any new medications, just observation and data collection. The exact number of visits or assessments will be explained by the study team, but it's a long-term study, so it will involve follow-ups over several years.

Potential risks and benefits

Taking part in this study won't offer a direct benefit to your health, but the information you provide will be incredibly valuable to researchers trying to understand and find treatments for dementia. The main benefit is contributing to scientific knowledge that could help future generations. Risks are generally low, mainly related to the time commitment for assessments, and potentially some discomfort if samples like blood are taken. Your personal information will be kept confidential. Remember, you can choose to leave the study at any time without giving a reason, and it won't affect your medical care.

Locations (1)

  • Scottish Brain Sciences Arran Facility
    Edinburgh, United Kingdom· Recruiting

Common questions

What is the main goal of the IONA study?

The main goal is to understand how diseases that cause memory and thinking problems, like dementia, develop and progress in people over time.

Will I receive new medicine as part of this study?

No, this study is about observation and understanding, not about testing new medicines. You won't be given any new treatments as part of the IONA study.

What kind of information will the study collect about me?

Researchers will collect information about your memory and thinking, lifestyle, general health, genetic details, and certain biological markers.

Do I have to live in Scotland to join?

Yes, a key requirement for this study is that you must be living in Scotland.

Can I stop participating in the study if I change my mind?

Yes, absolutely. You can withdraw from the study at any time, for any reason, and it will not affect your medical care.

How to find out more

Sarah Gregory, PhD

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "IONA Longitudinal Cohort Study…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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