Wessex Asthma Cohort of Difficult Asthma
The Wessex Asthma Cohort of Difficult Asthma (WATCH) is a study for people with severe asthma treated at University Hospital Southampton. We know asthma affects everyone differently, and even with new treatments, many people still have very challenging symptoms. This study aims to understand why some people continue to suffer and how we can better help them. Researchers gather detailed information during your regular hospital appointments, including how you feel, lung tests, and some samples like blood. This helps build a picture of severe asthma in real-life situations. The goal is to learn more about the different types of severe asthma and find better ways to treat it, ultimately leading to more personalised care.
At a glance
What is this study about?
Asthma can be really tough, especially for those with severe forms where regular medicines don't seem to work well enough. Even though we have new treatments, many people in the UK still struggle daily with their asthma. This costs a lot of money and can impact daily life, making it hard to go to school or work. We now understand that asthma isn't just one condition; it's more like several different types, each with its own causes and triggers. Because of this, what works for one person might not work for another.
The WATCH study, based at University Hospital Southampton, is looking at adults who have severe asthma and are already being seen by specialists there. This isn't a study where you get a new, untested drug. Instead, it's about collecting detailed information during your usual appointments. This information includes things like your medical history, how you're feeling, measurements of your lung function, and sometimes even samples of blood or urine. This helps researchers get a really clear picture of your specific type of asthma.
By gathering all this information from many different people over time, the WATCH study hopes to understand why some people's asthma is so difficult to control. The aim is to find out more about the different ways severe asthma shows up and how it progresses. This knowledge is key to developing more effective and personalised treatments in the future, meaning doctors can better match the right treatment to each individual's needs.
Key takeaways
- A study for adults with severe asthma at University Hospital Southampton.
- Aims to understand why some people still struggle with severe asthma.
- Information is collected during your regular clinic appointments.
- No new treatments are given, and no extra hospital visits are needed.
- Your participation helps improve future understanding and treatment of asthma.
Who may be eligible?
The WATCH study is looking for adults aged 18 to 99 who are already receiving specialist care for their asthma at University Hospital Southampton. You would typically be referred to these specialist clinics by your GP or another doctor because your asthma is considered particularly severe.
To be included, you need to be on high-dose asthma medications, which might also include regular or frequent use of steroid tablets, or other medicines that help reduce the need for steroids. These are the usual treatments given for more severe asthma, as advised by UK asthma guidelines.
If you don't attend these specific specialist asthma clinics at University Hospital Southampton, or if your asthma isn't severe enough to require these high-dose treatments, you wouldn't be able to join this particular study.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you an adult (18-99 years old)?
- Are you a patient at the specialist asthma clinics at University Hospital Southampton?
- Are you currently on high-dose asthma medicines, potentially including regular steroid tablets?
- Have you been told your asthma is 'difficult' or 'severe'?
- Are you happy for researchers to use information from your routine care?
What does participation involve?
If you decide to take part in the WATCH study, you won't need to make any extra visits to the hospital. All the research information will be collected during your usual, scheduled appointments at the specialist asthma clinic. During these appointments, you might be asked to fill out questionnaires about your health and how your asthma affects you. You'll also have standard checks like lung function tests and measurements of your height and weight. Occasionally, you might have imaging scans like X-rays, and some blood, urine, or phlegm samples might be collected. These are all things that are often part of your regular clinical care for severe asthma anyway. You'll continue to receive your usual asthma treatment from your doctors during the study. The study doesn't have a fixed end date for individuals; the aim is to follow participants over time to see how their asthma changes, so you could be part of it for several years, as long as you remain a patient at the clinic.
Potential risks and benefits
Locations (3)
- Portsmouth Hospitals NHS TrustVerified postcodePortsmouth, United Kingdom
- University Hospital Southampton NHS Foundation TrustVerified postcodeSouthampton, United Kingdom
- Isle of Wight NHS TrustVerified postcodeNewport, United Kingdom
Common questions
Will I get a new treatment if I join this study?
No, this study doesn't test new treatments. It's about collecting information during your usual doctor visits to better understand severe asthma.
Do I have to do extra hospital visits for the study?
No, all study information is collected during your regular appointments at the specialist asthma clinic.
Will taking part affect my regular asthma care?
No, your medical care will not change. You will continue to receive the best treatment from your doctors as usual.
What kind of information will you collect about me?
We'll collect information from questionnaires, lung tests, and sometimes blood or urine samples, all as part of your normal care.
Can I stop being part of the study if I change my mind?
Yes, you can choose to leave the study at any time, and it won't affect your medical care.
How to find out more
Always speak to your GP or specialist before deciding to take part in a study.
Discussion
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