Active not recruitingOBSERVATIONAL

A Study of Tumor Imaging With Multispectral Optoacoustic Tomography

This study is testing a new imaging method called Multispectral Optoacoustic Tomography, or MSOT. We want to see how well MSOT can image suspicious areas in the breast. If you're taking part, you would have this MSOT scan of both breasts just before your planned breast biopsy. This new scan will help researchers understand if MSOT can give doctors clearer pictures of breast tissue. After the MSOT scan, your part in the study would be finished. The goal is to see if this imaging technique could eventually help improve how breast cancer and melanoma are diagnosed and monitored. It's an important step in exploring new medical technologies.

At a glance

Status

Active not recruiting

Sponsor

Memorial Sloan Kettering Cancer Center

Enrolment target

Start

27 Jul 2022

Estimated completion

27 Jul 2026

Breast Cancer Melanoma

What is this study about?

This study is about a new imaging technique called Multispectral Optoacoustic Tomography, or MSOT for short. We're looking into whether MSOT can provide useful images of the breast, especially when doctors are checking for breast cancer or melanoma. Think of it like a new type of camera that helps us see things in the body in a different way than a standard ultrasound or mammogram.

Currently, when doctors find something suspicious in the breast, they often do a biopsy. This study wants to see how the new MSOT imaging works right before that biopsy. By getting a quick MSOT scan just before the planned biopsy, researchers can compare the MSOT images with what they learn from the biopsy. This helps them understand what the MSOT images are really showing.

The main goal is to find out if MSOT can improve how we see and understand suspicious areas in the breast. If it works well, this technology could potentially help doctors in the future to get more detailed information about breast tissue, which might lead to better ways to diagnose and monitor conditions like breast cancer and melanoma. It's an important step in developing new tools for healthcare.

Key takeaways

Tests a new imaging method called MSOT.
MSOT scan happens just before a planned breast biopsy.
Study is for breast cancer and melanoma research.
Participation is very brief – just one scan.
Aims to improve future diagnostic tools.

Who may be eligible?

To join this study, you need to be an adult aged 18 or older. It is for both women and men. You would be considered if you have a suspicious area in your breast that a doctor has recommended for an ultrasound-guided biopsy. This means something was seen on a mammogram, ultrasound, or MRI that looks concerning (classified as BI-RADS 4 or 5) and can be seen with an ultrasound. You also cannot have had previous treatment for breast cancer.

Another group of people who can join are those who have a diagnosis of melanoma, regardless of breast findings.

However, you cannot take part if your doctor believes you have less than 3 months to live. The study is specifically looking for women.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Are you a woman or a man?
Have you been told you need an ultrasound-guided breast biopsy for a suspicious finding?
OR have you been diagnosed with melanoma?
Have you not had previous treatment for breast cancer?
Do you expect to live for more than 3 months?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, your involvement would be very brief. All that's required is having an MSOT scan of both breasts. This scan will happen right before your scheduled ultrasound-guided breast biopsy. The MSOT scan is the only procedure you'll undergo for the study. Once the MSOT imaging is finished, your participation in the study will end. There are no follow-up appointments, additional medications, or other assessments beyond this single imaging session.

Potential risks and benefits

Taking part in this study might offer a small potential benefit in that you would receive a new type of breast scan (MSOT) which is being studied to see its effectiveness. While this specific scan is for research, it could contribute to future improvements in diagnosis. As for risks, the MSOT imaging is generally considered safe and non-invasive, meaning it doesn't involve needles or radiation. You have the right to withdraw from the study at any time without giving a reason, and this won't affect your medical care.

Locations (4)

Memorial Sloan Kettering Bergen (Consent only )
Verified postcode
Montvale, United States
Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Consent only)
Verified postcode
Commack, United States
Memorial Sloan - Kettering Cancer Center
Verified postcode
New York, United States
Helmholtz Institute (Data Analysis Only)
Verified postcode
Munich, Germany

Common questions

What is MSOT imaging?

MSOT (Multispectral Optoacoustic Tomography) is a new type of scan that uses light and sound to create detailed pictures inside the body, like a special camera.

Will this scan replace my biopsy?

No, this MSOT scan is done *before* your planned biopsy. It's for research to see if MSOT can give doctors more information, but your biopsy is still needed for diagnosis.

How long does the MSOT scan take?

The study doesn't specify the exact duration, but it's typically a quick, non-invasive imaging process.

Will I get results from the MSOT scan?

The study is focused on research, so the MSOT images might not be used for your immediate diagnosis or treatment, but they will help scientists learn more.

Can men take part in this study?

Yes, both women and men who meet the other requirements can be considered for this study, though it is specifically looking for women.