RecruitingOBSERVATIONAL

Met Non Small Cell Cancer Registry (MOMENT)

This study, called MOMENT, is a registry for people with a specific type of advanced lung cancer (non-small cell lung cancer, or NSCLC) that has a particular change in their genes called METex14. It's not a clinical trial testing new drugs, but rather a way for doctors to keep track of patients over time. The aim is to collect information on how people with this cancer are being treated and how they are getting on with their current care. This includes looking at their health, the treatments they receive, and how well those treatments are working. By gathering this up-to-date information, researchers hope to better understand this type of lung cancer and improve care in the future. You will receive your usual care, and your doctors will simply share some of your health information with the study.

At a glance

Status

Recruiting

Sponsor

EMD Serono Research & Development Institute, Inc.

Enrolment target

700

Start

04 Oct 2022

Estimated completion

28 Apr 2028

Cancer

What is this study about?

The MOMENT study is a type of research called a 'registry.' Imagine a big, organised notebook where doctors and researchers from different countries write down important information about real patients who have a specific health condition. In this case, the condition is a type of advanced lung cancer called non-small cell lung cancer (NSCLC) that has a particular genetic change known as METex14 skipping.

The main goal of this registry is simple: to collect up-to-date, high-quality information on how this type of lung cancer is being treated and how people are doing over time. This helps researchers understand if treatments are improving, if new treatments are being used, and what the long-term effects are. Because it's a registry, you won't be given any new or experimental treatments; you'll continue to receive the care your own doctor thinks is best for you.

Researchers will gather details like your general health, specific features of your cancer (including those genetic changes), the treatments your doctor chooses for you, and how well they work. They will also look at any side effects you might experience. All this information is brought together anonymously to give a clearer picture across many patients. This helps the medical community learn more about this specific type of lung cancer and how best to manage it in the future, potentially leading to better care for everyone.

Key takeaways

It's a registry, not a drug trial – you get your usual care.
Helps doctors learn more about advanced NSCLC with METex14 changes.
Your normal doctor's visits and treatments are simply recorded.
No new medications or extra procedures for you.
Your personal details are kept private and secure.
You can stop participating at any time without affecting your care.

Who may be eligible?

To be part of this study, you would need to meet a few key requirements. Firstly, you must agree to take part by signing a consent form. This shows you understand what the study involves.

Secondly, you need to have advanced non-small cell lung cancer (this means stages IIIB or IV) and your cancer must show a specific genetic change called 'METex14 skipping.' This change needs to have been found through a reliable test. Finally, you would either be just starting a new regular cancer treatment or already be receiving one.

It's important to know that you can't join this registry if you are already taking part in another clinical trial where new treatments are being tested. The MOMENT study focuses on standard, everyday care, not new drug trials.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Have you signed a consent form to join?
Do you have advanced non-small cell lung cancer?
Does your cancer have the 'METex14 skipping' genetic change?
Are you starting or already receiving regular cancer treatment?
Are you NOT currently in another clinical trial testing new treatments?

Answer every question to see your result.

What does participation involve?

If you join the MOMENT study, your participation will be very simple for you. You won't have any extra doctor's visits, tests, or treatments specifically for the study. You will continue to have your appointments and receive all your care exactly as your current doctor decides, based on what they believe is best for you. The study does not tell your doctor what to do.

What happens is that your doctor and their team will share some of your routine health information with the study. This includes things like your age, some details about your cancer, the treatments you are receiving, and how you are responding to them. This information will be collected over time as part of your regular check-ups. The study isn't about specific medications or giving you experimental treatments; it's about observing and recording what's happening in your normal care journey. The total duration of your participation will depend on how long your doctor continues to follow your care for your condition.

Potential risks and benefits

Because this study only involves collecting information from your routine care and doesn't involve any new treatments or procedures, there are no direct risks to your health. Your medical care will remain entirely in the hands of your doctor. The main benefit is that the information gathered from your journey, combined with that of many other patients, will help doctors better understand this specific type of lung cancer and its treatments. This could lead to improved care and options for future patients. You are free to withdraw from the study at any time without affecting your medical care.

Locations (64)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

Holy Cross Health
Verified postcode
Fort Lauderdale, United States· Recruiting
The Ohio State University Wexner Medical Center
Verified postcode
Columbus, United States· Recruiting
Vanderbilt University Medical Center
Verified postcode
Nashville, United States· Active not recruiting
Klinikum Klagenfurt Am Woerthersee
Verified postcode
Klagenfurt, Austria· Recruiting
Klinik Floridsdorf
Verified postcode
Vienna, Austria· Recruiting
AZ Delta
Verified postcode
Roeselare, Belgium· Recruiting
AZ Nikolaas
Verified postcode
Sint-Niklaas, Belgium· Recruiting
Ottawa Hospital General Campus
Verified postcode
Ottawa, Canada· Recruiting
Princess Margaret Cancer Centre
Verified postcode
Toronto, Canada· Recruiting
FN Olomouc
Verified postcode
Olomouc, Czechia· Recruiting
University Hospital Na Bulovce
Verified postcode
Prague, Czechia· Recruiting
Centre Hospitalier de Cholet
Verified postcode
Cholet, France· Recruiting

Common questions

What kind of study is MOMENT?

It's a 'registry' study, which means it collects information about how people are being treated for a specific lung cancer and how they get on over time. It's not testing new medicines.

Will I get any special treatment or medicine?

No, you will continue to receive the standard medical care your own doctor thinks is best for you. The study simply records information from your regular care.

Do I need extra doctor's appointments for this study?

No, you won't have any additional appointments or tests beyond your usual medical check-ups for your condition.

Will my personal details be shared?

The information shared will be anonymised, so your name and direct personal details won't be linked to the data when it's analysed by researchers.

Can I leave the study if I change my mind?

Yes, you can decide to stop participating at any time, and it will not affect your medical care.

How to find out more

US Medical Information

emediusa@emdserono.com 888-275-7376 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.