- recruiting
Effects of Oncological Treatment During Pregnancy on Mother and Child
This study looks at how cancer and its treatments during pregnancy affect mums and their babies. Researchers want to see if babies exposed to treatments like chemotherapy develop normally, and they'll also track the mothers' health.
United States · Argentina · Austria - recruitingNA
The Therapeutic Effect of Expressive Writing.
This study explores how writing about cancer, especially using a kind and understanding approach, affects well-being. It looks at how people with cancer feel about their bodies and their overall happiness by comparing two types of expressive writing.
United Kingdom - recruitingPHASE3
Randomized Controlled Trial of Remote Symptoms Monitoring With Resilience PRO Compared to Care As Usual Only
This study looks at whether a phone app, Resilience PRO, can help improve the quality of life for cancer patients undergoing treatment. It aims to see if regular symptom reporting through the app, which alerts care teams to important changes, makes a difference compared to standard care.
France · Germany - recruitingNA
Mainstreaming Genetics: Evaluation of a Digital Application to Scale and Spread Oncologist-initiated Genetic Testing
This study looks at a new digital tool called GA-Mainstream. It helps people with certain cancers like breast, ovarian, and colon cancer understand genetic testing better. The goal is to make sure patients feel informed and supported while getting tested for genes that can affect their cancer treatment.
Canada - recruitingNA
Strategy for EArly Recognition of Cancer, COPD & Heart Failure in the Emergency Department
This study at Queen Elizabeth University Hospital checks if a computer program can help doctors find heart and lung problems like cancer earlier from chest X-rays. It aims to improve how quickly and accurately these conditions are diagnosed.
United Kingdom - not yet recruitingNA
Finding My Way-UK: Promoting Positive Psychological Outcomes in People Living With and Beyond Curatively Treated Cancer
This study looks at an online program, "Finding My Way-UK", for people who have finished cancer treatment. It checks if the program is easy to use and helpful for improving feelings like hope and resilience after cancer.
United Kingdom - active not recruitingPHASE3
An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial
This study is for people who have already been taking a medicine called venetoclax for their cancer in another trial. It allows them to keep taking venetoclax if it's helping them and they're not having bad side effects, so doctors can learn more about its long-term safety.
United States · Australia · Austria - recruiting
Met Non Small Cell Cancer Registry (MOMENT)
This study looks at how treatments for a specific type of lung cancer (NSCLC with METex14 changes) are working in real patients and how patients are doing over time. It's a way to learn more about this cancer and its treatments without testing new medicines.
United States · Austria · Belgium - recruitingNA
Bliss DTx Assessment During Course Care Including Port-A-Catheter Setting
This study looks at a new virtual reality (VR) tool called Bliss DTx for managing pain and stress when a Port-a-Cath is put in. It compares VR to standard pain relief methods to see if it works as well.
France - active not recruitingPHASE2
Acute Immunological Effects of Exercise in Cancer Patients
This study looks at how a single session of intense exercise affects the immune system in young people with cancer compared to healthy individuals. We want to understand if exercise can help the body fight illness during cancer treatment.
Germany - recruiting
Prospective Hyperthermia Database in Cancer Patients (HT Register)
This study is gathering information about cancer patients treated with hyperthermia at Charité hospital. It aims to understand how well hyperthermia works in real-world settings, identify any risks, and improve treatments. Patients are followed to see how their cancer responds and if they experience side effects.
Germany - active not recruitingPHASE1
IMA401 TCER® in Recurrent and/or Refractory Solid Tumors, Alone or in Combination With a Checkpoint Inhibitor
This study is testing a new medicine, IMA401, for people with advanced cancers that have come back or haven't responded to other treatments. We want to see if it's safe, how well people tolerate it, and if it can help shrink tumours, either alone or with another cancer drug called pembrolizumab.
Germany - recruiting
Feasibility and Acceptability of Collecting Sociodemographic Data in CCTG Trials
This study asks people with cancer in clinical trials to share information about their lives, like their income, education, and housing. It helps researchers understand what makes it easier or harder for people to join research and get healthcare.
Canada - recruitingPHASE1, PHASE2
IMA402 T Cell-Engaging Receptor Molecule (TCER®) in Recurrent and/or Refractory Solid Tumors
This study is testing a new medicine, IMA402, for adults with advanced or returning solid cancers that haven't responded to other treatments. We want to see if it's safe, what dose works best, and if it can help shrink tumours.
Germany · Netherlands - recruitingNA
Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers
This study looks at using MRI scans for sigmoid colon cancer to see if it helps doctors plan better treatment. Half of patients get standard care (CT scan), and the other half get an additional MRI. We compare how plans change and follow up for improved care.
United Kingdom - active not recruiting
Care Pathways and Disparities in Care for Older Patients With Cancer: Typology, Determinants and Effect on Prognosis ( PASSAGE )
This study looks at how older people with cancer are cared for in hospitals. It aims to understand how their different health conditions affect their treatment and recovery, hoping to improve care for them in the future. It's about making sure older cancer patients get the best possible care.
France - recruitingNA
Rehabilitation of Taste and Smell Disorders Associated With Chemotherapy Using Aromatherapy
This study looks into using aromatherapy to help cancer patients who have changes in their taste and smell because of chemotherapy. We want to see if essential oils can improve these side effects, similar to how they've helped with smell loss from COVID-19, potentially making daily life better.
France - not yet recruitingPHASE2, PHASE3
DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.
This study looks at two drugs called dabrafenib and trametinib for various cancers with a specific gene change (BRAF V600). These drugs are already approved for some cancers and researchers want to see if they can help people with other rare cancers or cancers with this same change.
United Kingdom - recruiting
Is the 1939 Cancer Act Fit for Purpose in the Modern Technology Era?
This study looks at how the 1939 Cancer Act, which stops cancer treatments from being advertised to the public, works in today's internet age. It asks patients and healthcare workers for their views on online cancer information and how to update the law safely.
United Kingdom - recruiting
To Assess the Correlation of High-resolution Specimen PET-CT Imaging, Using the XEOS AURA 10 PET-CT, With the Histopathology Results and Long-term Outcome of Patients Undergoing Resective Cancer Surgery.
This study looks at how well a special scan, called PET-CT, works on removed cancer tissue. It compares these scans with lab results and patient health over time to see if this technology can improve cancer care and treatment decisions.
Belgium · United Kingdom - recruiting
Investigating the Tumour Immune Response of Radiotherapy
This study looks at how radiotherapy for cancer affects the body's immune system. Researchers will collect tiny tissue samples (biopsies) and blood before and after treatment to understand these changes in different cancer types.
United Kingdom - not yet recruitingNA
Three Times Weekly Symptom Screening for Children With Cancer
This study looks at how easy it is for children with cancer or their parents to use a website called SPARK. They'll use SPARK three times a week for 8 weeks to report symptoms, helping doctors manage their care better.
Canada - recruitingNA
Exploration of Adaptive Antitumoral Immune Cells Through Lymphapheresis in Cancer Patients : ALCYTA
This study looks for special immune cells in cancer patients who might be responding well to treatment or experiencing side effects. We want to understand how their immune system fights cancer.
France - enrolling by invitation
Retrospective WGS Study
This study looks back at records of children and young people with cancer who had a special genetic test called whole genome sequencing. The aim is to see if this test helped doctors choose better treatments for them, to understand its benefits.
United Kingdom - recruiting
MR-BIO: A Study to Evaluate Changes in MR Imaging and Biological Parameters
This study uses a special MRI machine to see how radiotherapy affects cancer and healthy tissues. It aims to improve treatment by understanding these changes and linking them to how well patients recover. Patients will give blood and urine samples.
United Kingdom - active not recruitingNA
Digital Body Mindset Intervention for Young Cancer Survivors
This study looks at whether a digital programme called EMBody can help young cancer survivors (aged 16-25) feel better about their bodies and improve their overall health and happiness. It uses short films and activities developed with survivors and doctors.
United Kingdom - recruiting
ORganoid GeneratioN Study for Cancer
This study aims to grow cancer cells from patient samples in the lab, like 'mini-tumours.' This helps scientists understand why some cancers respond to treatments and others don't, hopefully leading to better treatments for cancer patients in the future.
United Kingdom - recruitingNA
The PRIMROSE Trial
This study looks at how a special breathing device, used alongside standard pre-surgery exercises, can help people with lung cancer prepare for surgery. The aim is to make them fitter, reduce complications, and shorten their time in hospital.
United Kingdom - recruitingPHASE2, PHASE3
DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations
This study is testing a cancer drug called capmatinib to see if it can help adults with different types of cancer that share a specific genetic change (MET mutation). It's already approved for some lung cancers, and now researchers want to know if it works for other cancers too.
United Kingdom - recruiting
Management of Immune Checkpoint Inhibition-related Hepatitis Using Low-dose Corticosteroids
This study looks at using a lower dose of steroids to treat liver problems (hepatitis) caused by cancer immunotherapy. It aims to see if this smaller dose works well, reducing side effects, and helping patients get better without needing stronger medicines.
Switzerland · United Kingdom - recruitingPHASE1
A Single- and Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY4066708 in Healthy Participants
This study looks at a new medicine called LY4066708 in healthy volunteers. We want to check it's safe, how well the body handles it, and how long it stays in the system. It's a first step to see if it could help with certain health conditions later on.
United Kingdom - not yet recruitingNA
Benefits of Early Collaboration Between Oncologists and Palliative Care Physicians in Cases of Unplanned Hospitalization for Patients With Metastatic Cancer
This study looks at how working together with palliative care doctors early on might help people with advanced cancer who are admitted to hospital unexpectedly. It aims to see if this team approach can lead to care that's better for patients.
France - recruiting
Performance Indicators and Impact on the Care Pathway of Sequencing on the SeqOIA and AURAGEN (Seqogen) Platforms for Oncology Patients
This study looks at how advanced genetic tests (genomic sequencing) help doctors treat cancer in France. It checks if these tests improve patient care, how quickly results are ready, and how hospitals share information, helping to improve future healthcare for cancer patients.
France - recruiting
Prospective Observational Study of a Precision Medicine Approach in Patients With Advanced Cancer
Researchers are looking at a new way to treat advanced cancer using 'precision medicine'. This means checking a person's cancer cells closely to find the best treatment for them. This study will follow patients in Berlin to see how well this approach works and if it helps them.
Germany - not yet recruiting
Hair Isotope Analysis for Early Cancer Detection
This study looks at hair to find early signs of cancer. We think cancer changes how your body uses nutrients, and this might show up in your hair. By analysing hair from people with cancer, we hope to find new ways to detect the disease simply and without needles.
United Kingdom - recruitingPHASE1
Impact of PEG Bowel Preparation on Gut Microbiome Composition Recovery
This study looks at how a common bowel cleansing drink, PEGLyte, affects the helpful germs (microbiome) in your gut. It aims to understand these changes and how quickly your gut returns to normal after taking the drink.
Canada - recruitingNA
Impact of a Collaborative Program of Physical Activity of Newly-diagnosed Cancer Patients
This study looks at how a special exercise programme helps people newly diagnosed with cancer. We want to see if a personalised plan works better than standard advice for staying active, which could improve quality of life and treatment tolerance.
France - recruitingNA
Optimization of Radiation Protection Through Genomic Analyses
This study looks at how radiation affects our DNA by using new genetic tests. We want to find ways to measure radiation exposure, understand its effects, and predict how well someone might recover from it. This helps improve safety from radiation.
Germany - recruitingPHASE2
Pan Tumor Rollover Study
This study looks at the long-term safety of different cancer treatments, including nivolumab, alone or combined with other medicines. It's for people with various types of cancer who are already receiving treatment in a related study, aiming to see how these treatments work over time.
United States · Argentina · Australia - recruiting
E²-RADIatE: EORTC-ESTRO RADiotherapy InfrAstrucTure for Europe
The E²-RADIatE study is collecting information from cancer patients across Europe who are having radiotherapy. This helps researchers better understand how radiotherapy is used and how it works alongside other treatments to improve care for people with cancer.
Austria · Belgium · Czechia - recruiting
Assessing Cancer Treatment Response to Therapy Using 18F-FSPG PET
This study investigates if a new scan, 18F-FSPG PET, can better show how well cancer treatments are working for lung and head & neck cancers. We're comparing it to standard scans to see if it predicts treatment success earlier.
United Kingdom - active not recruiting
Management of Bone Metastases
This study looks at how we treat bone issues in people with cancer, especially how often important bone-strengthening medicines are used. We want to understand what makes these treatments work best and help more patients.
France - recruitingNA
Impact of Virtual Reality on the Quality of Life of Oncology Patients
This study explores if virtual reality (VR) can help cancer patients, especially children, feel better during chemotherapy. VR aims to reduce anxiety, sickness, and pain, improving their overall comfort and quality of life while undergoing treatment. It also checks how happy patients and nurses are with the VR experience.
France - recruiting
Population-based Cancer Observatory
This study, called a Cancer Observatory, in France collects information on people with cancer. Researchers want to understand cancer trends, how well treatments and prevention plans work, and if where people live affects cancer risk. It's an observational study, meaning no medical treatments are given.
France - recruiting
LIVInG With chrONic Cancer TrEatments (LONGEVITI) Study
This study looks at how new cancer treatments affect daily life for people with long-term cancer. It aims to understand how to best support them while they are on these treatments, often for many months or years.
Canada - recruitingPHASE3
Abatacept in Immune Checkpoint Inhibitor Myocarditis
This study is looking into whether a drug called abatacept can help people with heart inflammation (myocarditis) caused by cancer treatment. It compares abatacept to a dummy drug (placebo) to see if it reduces serious heart problems.
United States · Canada - recruitingPHASE2, PHASE3
DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers.
This study is testing a drug called entrectinib for different cancers in adults and children. It focuses on cancers with a specific change in their cells, called ROS1 gene fusion, to see if entrectinib can be a new treatment option.
United Kingdom - recruitingNA
Analysis of Circulating Tumor mArkers in Blood 4 - ALCINA 4
ALCINA 4 is a study looking at cancer markers in blood. We want to see if a simple blood test can help us understand cancer better, perhaps even replacing painful biopsies. It won't change your current cancer treatment.
France - active not recruiting
Definition for the Assessment of Time-to-event Endpoints in CANcer Trials (DATECAN-1)
This study helps cancer researchers agree on how to measure important treatment effects like how long people live or how long their cancer stays stable. It aims to make sure everyone uses the same rules, so we can better compare different cancer treatments and improve care.
France - not yet recruitingNA
Peri-procedural Management of Direct Oral Anticoagulants for Central VENOus Catheters in CAncer Patients With Venous Thromboembolism or Atrial Fibrillation Pilot Study
This study looks at how best to manage blood-thinning medicines (DOACs) for cancer patients needing a special tube (CVC) inserted. It compares stopping DOACs briefly versus continuing them to see what's safest and most effective.
Canada