Chemotherapy-Induced Hearing Loss and Health Inequality
This research wants to understand how certain chemotherapy drugs (platinum-based chemotherapy) can harm hearing in cancer patients. We're particularly interested in how this affects people from different financial and social situations in the North West of England. We know these drugs can damage the tiny hair cells in the ear, leading to permanent hearing loss. People from less well-off backgrounds might be more at risk due to various reasons like harder access to healthcare or noisy jobs. The study also explores if this hearing loss makes it harder to think and remember, which can be extra challenging for people also experiencing 'chemo brain'. Finding these links will help doctors better support cancer patients and develop better ways to check for and help with hearing problems in the future.
At a glance
What is this study about?
This study is looking into a really important issue: how some types of chemotherapy used for cancer can cause hearing problems. Certain chemotherapy drugs, called platinum-based chemotherapy, are known to be strong and effective against cancer, but they can sometimes harm the delicate hair cells in your inner ear. When these cells are damaged, it can lead to hearing loss.
We're especially interested in how this might affect people from different financial and social backgrounds in the North West of England. We know that life circumstances can play a big role in health. For example, people from less wealthy areas might have a harder time getting to healthcare appointments, or they might have jobs that expose them to a lot of noise, which can already affect hearing. These factors could make them more vulnerable to hearing loss from chemotherapy. No one has really studied this closely before, so this research is vital to understand if certain groups are more affected than others.
Another key part of this study is to see if hearing loss, particularly after chemotherapy, can make it harder for people to think clearly and remember things. This is especially relevant for cancer patients who might also experience what's sometimes called 'chemo brain' – a feeling of fogginess or difficulty concentrating after treatment. If hearing loss makes it harder to follow conversations, it could put extra strain on the brain. By understanding these connections, we hope to find better ways to support cancer patients, make sure their hearing is checked, and help them maintain their quality of life and stay connected with others.
Key takeaways
- Certain chemotherapy drugs can cause permanent hearing loss.
- This study investigates if people from poorer backgrounds are more affected.
- Researchers will check if hearing loss links to difficulties with thinking and memory (chemo brain).
- Participation involves online hearing and thinking tests before and after chemotherapy.
- Findings will help improve future care and screening for cancer patients' hearing.
- The study focuses on patients in the North West of England.
Who may be eligible?
To join this study, you would need to be a cancer patient receiving certain types of chemotherapy drugs (known as platinum-based chemotherapy). You must live and be receiving your treatment in the North West of England. You also need to be comfortable using a computer or device to complete online hearing and thinking tests and be able to speak and understand English well.
There are some reasons why you wouldn't be able to join. For example, if you have certain types of cancer like a brain tumour or some head and neck cancers, or if you've previously had severe hearing loss as a child. You also couldn't join if you currently have an ear infection, use a cochlear implant, or have certain brain conditions like dementia or if you've recently had a stroke. The study also cannot include people who might have difficulty understanding what the study involves or completing the tasks.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- I am receiving platinum-based chemotherapy for cancer.
- I live and am being treated in the North West of England.
- I can use a computer or device for online tests and speak English well.
- I do not have specific types of cancer like brain tumours or serious pre-existing hearing/brain conditions.
What does participation involve?
The study involves completing some online tests to assess your hearing and thinking skills. These tests would be done before and after your chemotherapy treatment. The researchers would also look at information about your chemotherapy treatment, such as the dose you received and for how long. The total duration of your participation would depend on your chemotherapy schedule, as tests are done linked to your treatment journey. There are no extra medications involved in this study.
Potential risks and benefits
Locations (1)
- Lancaster UniversityVerified postcodeLancaster, United Kingdom
Common questions
What kind of chemotherapy is this study interested in?
The study focuses on 'platinum-based' chemotherapy drugs, like cisplatin, often used for various cancers.
What does 'chemo brain' mean?
'Chemo brain' is a common term for memory and thinking problems some people experience during or after cancer treatment.
How will my background affect the study?
The study aims to see if people from different economic and social backgrounds are affected differently by chemotherapy-induced hearing loss.
Will I get my hearing checked as part of this study?
Yes, your hearing will be assessed using online tests before and after your chemotherapy treatment as part of the study.
What happens with the information they collect?
The information will help guide future strategies for checking and helping cancer patients with hearing problems after chemotherapy.
How to find out more
Helen Nuttall
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
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