RecruitingOBSERVATIONAL

Evaluation of the Benefit of Exercise Testing for the Diagnosis of Obstruction in the Coronary Arteries of the Heart

This study aims to discover if a particular exercise test can effectively identify blockages in the heart's arteries. The main goal is to determine if this exercise test can help doctors understand your heart health, potentially reducing the need for more detailed scans in some people. Patients suspected of having coronary artery disease will ride an exercise bike while doctors monitor their heart and blood pressure. Later, they will also have a heart scan (either a CT scan or a coronary angiogram). By comparing the results of the exercise test with the scan results, researchers hope to see if the exercise test alone is good enough to diagnose artery blockages, thus making diagnosis quicker and less invasive for some.

At a glance

Status

Recruiting

Sponsor

Centre Hospitalier Sud Francilien

Enrolment target

120

Start

04 May 2022

Estimated completion

31 Dec 2025

Coronary Artery Disease

What is this study about?

This research is looking into how well a specific type of exercise test can help doctors find out if there are any blockages in the arteries that supply blood to your heart. These blockages are a sign of what's called coronary artery disease. The study wants to check if this exercise test can give enough information to diagnose the problem, potentially avoiding the need for more complex imaging tests like a heart CT scan in every case.

Here's how it works: People who might have coronary artery disease will do an exercise test on a special bike. As they pedal, the exercise gets harder, and doctors will carefully watch their heart activity using an ECG, their blood pressure, and other important signs. Each person in the study will also have a more detailed scan of their heart, either a cardiac CT scan or a coronary angiogram. This scan will show definitively whether there are any blockages in their heart arteries.

By comparing the results from the exercise test with the results from the heart scan, the researchers want to understand if the information from the exercise test alone is reliable enough to tell if someone has blocked arteries. If it is, this could mean that for some patients, a simple exercise test could provide the answers needed, making the diagnostic process easier and less invasive. The study aims to gather information from about 100 to 120 patients before March 2022.

Key takeaways

The study looks at whether an exercise test can spot blocked heart arteries.
It aims to reduce the need for more complex heart scans for some patients.
Researchers are using information from existing exercise tests and heart scans.
You won't have any extra tests or appointments for this study.
This research might help improve how heart problems are diagnosed in the future.

Who may be eligible?

To be included in this study, you need to be at least 18 years old. You must have had both an exercise test and a heart scan (either a Cardiac CT or a coronary angiogram) for your heart health within a three-month period. It's also important that you understand what the study is about and are happy to take part.

Unfortunately, if you're unable to fully understand the details of the study and what it involves, then you wouldn't be able to participate. The study is open to both men and women across all adult age groups, from 18 years onwards.

The data for this study was collected from patients between January 1, 2019, and March 1, 2022.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Did you have an exercise test for your heart?
Did you also have a heart scan (CT or angiogram) within 3 months of that exercise test?
Do you understand what the study is about and are happy for your data to be used?
Are you able to fully understand the study information provided?

Answer every question to see your result.

What does participation involve?

This study doesn't ask you to undergo any new tests specifically for the research. Instead, it uses information from two tests you've already had as part of your regular medical care. The first is an "exercise test" where you cycle on a stationary bike while doctors monitor your heart. The second is a detailed "heart scan," which could have been either a cardiac CT or a coronary angiography. Both of these tests must have taken place within three months of each other.

Researchers will simply look at the results of these existing tests. You won't need to visit the hospital extra times for this study, take any new medications, or have any follow-up appointments directly related to the research. Your participation involves allowing your medical records from these two tests to be included in the study for analysis. There is no specified total duration for your direct involvement beyond the initial tests.

Potential risks and benefits

Since this study only uses information from tests you've already had as part of your normal care, there are no additional risks to you for taking part. You won't undergo any new procedures. The potential benefit is that the study might help doctors better understand how to diagnose heart artery problems in the future, potentially leading to simpler diagnostic methods for others. Remember, you have the right to decide if you want your anonymised information to be used in this study, and you can withdraw your permission at any time without it affecting your medical care.

Locations (1)

CHARANSONNEY Olivier
Verified postcode
Corbeil-Essonnes, France· Recruiting

Common questions

What is coronary artery disease?

It's a common heart condition where the main blood vessels that supply the heart become blocked or narrowed, often leading to chest pain or heart attacks.

What is an exercise test?

It's a test where you exercise on a bike or treadmill while doctors monitor your heart's activity, blood pressure, and other vital signs to see how your heart handles stress.

What is a cardiac CT or coronary angiography?

These are special types of scans that take detailed pictures of your heart's arteries to check for blockages or narrowing.

Will taking part in this study change my medical care?

No, this study only uses information from tests you've already had. It won't change your current or future medical treatment in any way.

What will happen to my personal information?

Your personal details will be kept confidential. Researchers will look at your test results in a way that protects your identity.

How to find out more

Olivier CHARANSONNEY, MD

olivier.charansonney@chsf.fr 0161697766 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.