Treatment of COVID-19 by Nebulization of Inteferon Beta 1b Efficiency and Safety Study

To be part of this study, you need to be at least 18 years old and have a confirmed COVID-19 infection that was diagnosed recently. You also need to be in hospital because of COVID-19 and require oxygen to help you breathe. Generally, patients should have been in hospital for less than 7 days and have had their COVID-19 symptoms for less than 10 days.

There are certain reasons why you wouldn't be able to join. For example, if you are allergic to Interferon Beta 1b or other ingredients in the medicine, such as albumin or mannitol. You also can't take part if you are pregnant or breastfeeding, have severe liver problems, or have had a recent suicide attempt. Patients with certain serious long-term illnesses like advanced cancer, severe heart failure, or those who have had a kidney transplant are also not able to participate. If you're on a breathing machine (mechanical ventilator) or have a severe fungal infection, this study wouldn't be suitable for you.

If you decide to take part in this study, you would begin by breathing in the study medicine or a dummy treatment (plain water) through a nebuliser. This device turns the liquid into a fine mist for you to inhale. We'd closely monitor your oxygen levels and overall health during your hospital stay. You might have extra blood tests, nose or throat swabs, and lung function assessments to see how well the medicine is working and how you are responding. The exact number of visits and tests would depend on your individual treatment plan and how you recover. We would continue to follow your progress while you are in the hospital. The total length of your participation would be for the duration of your hospital stay and possibly a short follow-up period after you go home.