- recruitingPHASE3
EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease
This study is looking at a medicine called nirmatrelvir/ritonavir for children and young people under 18 with COVID-19. It aims to see how safe and effective it is for those who aren't in hospital but are at higher risk of getting seriously ill.
United States · Bulgaria · Japan - recruiting
Hospitalised COVID-19 Patients Cohort Study in the EuCARE Project
This study looks at hospitalised COVID-19 patients across the world. Researchers want to understand how different types of the virus and vaccination affect how ill people get and how they recover. They're collecting patient information and some blood samples to learn more.
Germany · Italy · Kenya - recruiting
Brain Imaging in Babies Study
This study looks at how babies' brains develop from before birth until they are 3-4 years old. Researchers use safe brain scans and check children's behaviour to understand brain growth. They also want to see if they can predict conditions like autism and ADHD early on, and how COVID-19 might affect brain development.
United Kingdom - recruiting
Post COVID-19 Condition
This study looks at how many people get Long COVID and what might lead to it. It follows adults who have recovered from COVID-19 to understand the long-lasting health effects. The goal is to learn why some people continue to feel unwell months after having the virus.
Germany · Italy · Lithuania - recruiting
Longitudinal Population-based Observational Study of COVID-19 in the UK Population
COVIDENCE UK is a study looking at how COVID-19 affects people across the UK. Researchers want to understand who gets sick, how the illness progresses, and its long-term effects on physical and mental health. This helps us learn more about the virus.
United Kingdom - active not recruiting
COVID-19 Symptom Tracker
This study uses a free app to track COVID-19 symptoms and how the illness progresses. It also looks at how isolation impacts people's well-being. The goal is to learn more about the virus and help tell it apart from common colds.
United States · United Kingdom - ongoing, recruitingTherapeutic exploratory (Phase II)
A 4-week double-blind, randomized, placebo-controlled, phase II study evaluating the effects of oral pamapimod 150 mg with pioglitazone 10 mg daily on COVID-19 evolution and recovery in non-hospitalized patients infected with SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2)
This study looks at how two medicines, pamapimod and pioglitazone, might help people with COVID-19 who don't need to be in hospital. It aims to see if they can help people get better faster and reduce their symptoms. Participants will take one of the study medicines or a dummy pill for 4 weeks.
Germany - ongoing, recruitingTherapeutic confirmatory (Phase III)
A Multicenter, Adaptive, Randomized, Controlled Trial Platform to Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections: Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE) - Shionogi Protease Inhibitor (S-217622)
This study is looking into a new medication called S-217622 for people in hospital with COVID-19. It aims to see if the medication is safe and helps people recover faster. They will compare it to a dummy treatment.
Spain · Germany · Greece - ongoing, recruitingPhase III and phase IV (Integrated)
Prospective Randomized trial of Everolimus replacing MMF/MP Acid by the RECOVAC consortium to increase VACcine response in kidney transplant patients
This study looks at how well kidney transplant patients respond to COVID-19 and shingles vaccines when their anti-rejection medication is changed. It compares two different drug treatment plans to see which one helps the body make more protective antibodies.
Netherlands - ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Bemnifosbuvir in High-Risk Outpatients with COVID-19
This study is testing new treatments for COVID-19 in people who are at higher risk of becoming very unwell. It compares a new medicine called Bemnifosbuvir with usual care and Paxlovid to see if it helps prevent serious illness or hospital stays.
Latvia · Netherlands · Sweden - ongoing, recruitingTherapeutic confirmatory (Phase III)
A Multicenter, Adaptive, Randomized, Controlled Trial Platform to Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections: Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE) - Immune Modulation Strategy Trial
This study is looking at new ways to treat adults in hospital with COVID-19. We're testing a medicine called Orencia against a dummy treatment to see if it helps people recover faster and has fewer side effects. It's a big study to find the best care.
Denmark · France · Sweden - ongoing, recruitingPhase II and Phase III (Integrated)
A Phase 2/3 Single-Arm, Open-label Study to Evaluate the Safety, Pharmacokinetics and Efficacy of Obeldesivir in Pediatric Participants With COVID-19
This study is looking at a new medicine called Obeldesivir for children with COVID-19. Researchers want to see if it's safe, how the body uses it, and if it helps children recover. They are testing two different dose strengths.
Poland · Spain · Italy - ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase I/III Randomized, Double-blind Study to Evaluate the Safety, Efficacy, and Neutralizing Activity of AZD5156/AZD3152 for Pre-exposure Prophylaxis of COVID-19 in Participants with Conditions Causing Immune Impairment
This study is testing a new medicine, Sipavibart (also called AZD5156/AZD3152), to see if it can prevent COVID-19 in people with weaker immune systems. It compares the new medicine to an existing one called Evusheld or a dummy treatment, focusing on how safe and effective it is.
Spain · France · Germany - authorisedHuman Pharmacology (Phase I)- Other
Treatment of Respiratory Complications Associated with COVID-19, Influenza A, Metapneumovirus, Respiratory Syncytial Virus (RSV) Infection Using Wharton’s Jelly (WJ)-Umbilical Cord (UC) Mesenchymal Stromal Cells (ProTrans®): open Phase IB Clinical Trial
This study is testing a new treatment for serious breathing problems caused by viruses like COVID-19 and flu. It uses special cells from umbilical cords to help people aged 18 and over who are very ill get better. It's an early-stage study to see if the treatment is safe.
Sweden - recruiting
Serological and PCR Testing for COVID-19
This study is looking at different ways to test for COVID-19, including current infections and past infections. By doing this, researchers hope to better understand how the virus spreads and how our bodies fight it, which can help in developing better ways to manage the pandemic.
United Kingdom - active not recruiting
Burden for STaff Working in the NHS
This study looks at how the COVID-19 pandemic has affected the mental well-being of NHS staff. Researchers want to understand these effects to find better ways to support them now and in any future health crises. Participants will complete online surveys over time.
United Kingdom - ongoing, recruitingTherapeutic use (Phase IV)
A phase 4, open-label study to evaluate the short-term innate immune response after administration of a COVID-19 mRNA vaccine (Comirnaty JN.1®) in healthy adults aged 18 to 40 years.
This study looks at how a new COVID-19 vaccine (Comirnaty JN.1) affects the body's immediate protections. Researchers want to see changes in immune markers shortly after vaccination in healthy adults aged 18 to 40.
Belgium - ongoing, recruitingTherapeutic use (Phase IV)
A Phase IV, open label, single arm trial to assess the safety and immunogenicity of BIMERVAX® LP.8.1 against SARS-CoV-2 variants.
This study is looking at a new COVID-19 vaccine, BIMERVAX LP.8.1, to see how safe it is and how well it helps your body fight off different types of the virus, especially Omicron. It's for people who've already had the vaccine (Phase IV).
Spain