RecruitingOBSERVATIONAL

Hospitalised COVID-19 Patients Cohort Study in the EuCARE Project

This is a global study called EuCARE, focusing on people hospitalised with COVID-19. Doctors and researchers in many countries are collecting information about how patients get on. They are especially interested in how different versions of the COVID-19 virus (called 'variants'), and whether someone has been vaccinated (and with which vaccine), affect how severe their illness is and their recovery. The study aims to gather patient details and, for some, collect blood samples to understand how the body fights the virus. The information gathered will be used to improve future care and treatment for COVID-19 patients by understanding the impact of these viral variants and vaccines.

At a glance

Status

Recruiting

Sponsor

Euresist Network GEIE

Enrolment target

22,000

Start

23 Feb 2022

Estimated completion

13 Oct 2026

COVID-19

What is this study about?

This study, part of a bigger project called EuCARE, is looking at people who have been so unwell with COVID-19 that they needed to be admitted to hospital. It’s a large-scale study involving 12 hospitals in 11 different countries around the world. The main goal is to understand how the COVID-19 virus affects people differently.

Researchers want to see if the specific type of COVID-19 virus someone has (known as a 'viral variant', like Omicron or Delta) makes their illness more or less severe. They are also investigating how a person's vaccination status, including the type of vaccine received and how many doses, impacts their experience with COVID-19. By gathering this information, they hope to get a clearer picture of how these factors influence how sick someone gets, what treatments they receive, and how long it takes them to recover.

To do this, the study is collecting general health information from hospital records, both from the past and as new patients come in. For some patients, they're also collecting blood samples. These samples help them check things like how the body's immune system is fighting the virus and to identify the specific type of virus causing the illness. All this data will then be analysed carefully to provide recommendations for better care and treatment for COVID-19 patients in the future.

Key takeaways

It's a global study about hospitalised COVID-19 patients.
Researchers are looking at how different virus types and vaccines affect illness.
You would receive standard hospital care, no new treatments.
For some, blood samples may be collected during routine tests.
Your information helps improve future COVID-19 care for others.
Participation is during your hospital stay.

Who may be eligible?

To be considered for this study, you would need to be at least 18 years old and have been admitted to hospital with COVID-19. This includes patients who might arrive in the emergency department.

You must have tested positive for the SARS-CoV-2 virus (the virus that causes COVID-19) using a PCR test at some point from 14 days before you were admitted to hospital up until the time you leave. Both your first time having COVID-19 and any re-infections could be included.

Finally, if the rules of the study require it where you are, you would need to give your informed consent, which means you understand what the study involves and agree to take part.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Have you been admitted to hospital because of COVID-19?
Did you have a positive COVID-19 PCR test result around the time of your admission?
Are you able to give your agreement if required to take part?

Answer every question to see your result.

What does participation involve?

This is an 'observational' study, which means you wouldn't be given any new treatments or asked to do anything differently from your normal medical care. The study aims to collect information about your health and treatment while you are in hospital for COVID-19, which doctors would typically be recording anyway.

For some patients, researchers might also ask to collect a blood sample. This would be taken alongside any routine blood tests you might have during your hospital stay for medical reasons. There are no extra visits or long-term follow-up appointments after you leave the hospital specifically for this study. The total duration of your participation would cover the time you are in hospital.

Potential risks and benefits

Since this is an observational study that mainly gathers existing information and, for some, collects a blood sample at the same time as routine tests, the risks are very low. The main benefit is that your information will help doctors and scientists worldwide better understand COVID-19. This could lead to improved care and treatments for future patients. You always have the right to withdraw from the study at any time, and this will not affect your medical care.

Locations (10)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

Heinrich-Heine-Universität Düsseldorf
Verified postcode
Düsseldorf, Germany· Recruiting
ASST Santi Paolo e Carlo
Verified postcode
Milan, Italy· Recruiting
University of Rome Tor Vergata
Verified postcode
Rome, Italy· Recruiting
Kenya Medical Research Institute (KEMRI)
Verified postcode
Nairobi, Kenya· Recruiting
Vilnius universiteto ligoninė Santaros klinikos
Verified postcode
Vilnius, Lithuania· Recruiting
Regional Hospital Dr. Juan Graham Casasús, Villahermosa
Verified postcode
Villahermosa, Mexico· Recruiting
Centro Hospitalar Lisboa Ocidental
Verified postcode
Lisbon, Portugal· Recruiting
Karolinska Institutet
Verified postcode
Stockholm, Sweden· Recruiting
Poole University Hospitals, Dorset
Verified postcode
Poole, United Kingdom· Recruiting
Bach Mai Hospital
Verified postcode
Hanoi, Vietnam· Recruiting

Common questions

What is an 'observational study'?

It means researchers are watching and recording what happens naturally. You won't be given new medicines or treatments as part of the study; you'll receive your usual hospital care.

Will I have to take any new medication?

No, this study doesn't involve any new medications. You'll receive the standard care and treatments your doctors recommend for your COVID-19.

Will my personal details be kept private?

Yes, all your information will be handled confidentially. The study uses anonymised data as much as possible, meaning your name and direct identifiers are removed to protect your privacy.

What happens to the blood samples?

If taken, blood samples are used to understand how your body fights the virus and to identify the specific type of virus. They help researchers learn more about COVID-19.

How long will I be involved in the study?

Your involvement would be during your hospital stay for COVID-19. There are no extra appointments or follow-ups once you leave the hospital related to this study.

How to find out more

FRANCESCA INCARDONA Project Coordinator

francesca.incardona@euresist.org +393356112830 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.