Assessment of HGI (Hemoglobin Glycation Index) Variability Over Time in Patients Living With Diabetes Using Continuous Glucose Monitoring ( GAP OUEST )
This research study aims to understand how a specific measurement, called the Hemoglobin Glycation Index (HGI), varies over time in people who live with diabetes. Researchers will use continuous glucose monitoring (CGM) devices, which track blood sugar levels throughout the day, to collect this information. By looking at HGI, which can reflect how well blood sugar is controlled over weeks, researchers hope to learn more about its natural ups and downs. This could help doctors and patients get a clearer picture of long-term diabetes management and how best to use the information from blood sugar monitors.
At a glance
What is this study about?
This study, called GAP OUEST, is designed to help us understand a bit more about how diabetes affects people over time. Specifically, it's looking at something called the Hemoglobin Glycation Index (HGI). You might have heard of HbA1c, which is a blood test that shows your average blood sugar levels over the past 2-3 months. HGI is a measurement related to this, and it helps doctors understand how a person's average blood sugar levels compare to what they're seeing on their continuous glucose monitor (CGM).
Continuous glucose monitors are devices that wear on your body to automatically track your blood sugar levels throughout the day and night. They give a much more detailed picture than just checking your sugar a few times a day. By using these monitors, the study wants to see how much the HGI measurement naturally changes or 'varies' in people with diabetes over a period of time.
The main reason this research is important is to give doctors and patients more information. If we understand how HGI changes, it could help in tailoring diabetes treatment more precisely. It might also help people with diabetes use the information from their glucose monitors more effectively to manage their condition.
Key takeaways
- This study is about understanding diabetes better through blood sugar measurements.
- It uses data from continuous glucose monitors (CGMs).
- It looks at how a measure called HGI changes in people with diabetes.
- There are no new medicines involved in this study.
- Participation could help improve diabetes care for many people.
Who may be eligible?
To be part of this study, you need to be an adult, 18 years or older, with no upper age limit. You must also have diabetes that has been diagnosed for at least six months and regularly use a continuous glucose monitor (CGM) for at least three months. You should also be part of a social security scheme, like the NHS in the UK, or similar.
There are also some reasons why you might not be able to join. For example, if you have certain blood conditions (called hemoglobinopathy), or if your continuous glucose monitor isn't working correctly and hasn't captured enough data recently. You also can't take part if you have very severe kidney problems, or if you are pregnant or breastfeeding.
Also, if you've recently taken steroid medicines (in the last three months), or have had an infection or unusual activity recently that might affect your blood sugar, you might not be able to participate. The study team will make sure that joining the study is safe for everyone involved.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you 18 years old or older?
- Have you had diabetes for at least 6 months?
- Do you use a continuous glucose monitor regularly (for 3 months or more)?
- Are you currently not pregnant or breastfeeding?
- Do you have good kidney function (not severe kidney disease)?
- Have you avoided steroid medications in the last 3 months?
What does participation involve?
The study aims to understand how your HGI measurement changes over time. If you decide to take part, you'll need to agree to participate by signing a consent form. While the summary doesn't detail specific visits, assessments, medication, or follow-up, the core of the study involves using the information collected by your own continuous glucose monitor (CGM). This means that a significant part of your involvement will be continuing to use your CGM as you normally would. The study will then analyse the data from your device to see how your HGI changes. The total duration of your participation isn't specified, but the study focuses on 'variability over time', suggesting data will be collected over a period.
Potential risks and benefits
Locations (9)
- CHU d'AngersVerified postcodeAngers, France
- CHU de BrestVerified postcodeBrest, France
- CHU de CaenVerified postcodeCaen, France
- CH du MansVerified postcodeLe Mans, France
- CHU de NantesVerified postcodeNantes, France
- CHU de PoitiersVerified postcodePoitiers, France
- Hôpital NOVOVerified postcodePontoise, France
- CHU de RennesVerified postcodeRennes, France
- CHU de ToulouseVerified postcodeToulouse, France
Common questions
What is HGI?
HGI, or Hemoglobin Glycation Index, is a measurement that helps doctors understand how your average blood sugar levels compare to what your continuous glucose monitor shows.
What is a continuous glucose monitor (CGM)?
A CGM is a small device you wear that automatically tracks your blood sugar levels throughout the day and night, giving you a detailed picture of your glucose trends.
Will I have to take any new medicines?
No, this study doesn't involve taking any new medications. It aims to understand information from your existing glucose monitoring.
How long will I be in the study?
The information provided doesn't specify the exact length of time you'd be in the study, but it looks at changes 'over time,' suggesting a period of observation.
Can I stop being part of the study once I've started?
Yes, you can choose to leave the study at any point, and it won't affect your regular medical care.
How to find out more
Always speak to your GP or specialist before deciding to take part in a study.
Discussion
Community discussion
Powered by our forum at community.patient.info. Please be respectful — this is not medical advice.