A Technical Innovation of Prismatic Adaptation Test in Healthy Subject, in Favour of Autonomy and Independence in Daily Life Following a Brain Injury
This study aims to find new and better ways to help people who have a brain injury that causes something called unilateral neglect. This is when someone struggles to notice things on one side of their body or surroundings. This can make everyday life difficult. Currently, a therapy using special glasses (prismatic goggles) helps, but people often need to go to a hospital for it. We want to see if we can make this therapy available at home. We're testing two new approaches in healthy volunteers. One uses virtual reality to create the same visual effects as the special glasses. The other involves imagining movements without actually doing them. The goal is to see if these new methods work in a similar way to the traditional therapy. If successful, this could mean more people can access this helpful treatment easily from their own homes, improving their independence and quality of life.
At a glance
What is this study about?
When someone has a brain injury, sometimes it can affect how they see and respond to the world around them. One specific problem is called 'unilateral neglect'. This means they might struggle to notice things on one side of their body or the space around them – for example, they might only eat half the food on their plate or bump into things on one side. This can make everyday tasks very difficult and frustrating, making it harder for them to live independently.
There's a therapy where people wear special glasses with prisms. These glasses shift what you see, and by practising pointing at targets, your brain gradually adjusts. This helps to improve the neglect. While this therapy is promising, it often requires people to visit a hospital or clinic, which can be difficult to do regularly or for a long time. Because of this, it's hard to know how long the benefits of the therapy last or what the best way to use it is.
This study wants to find new ways to make this helpful therapy more accessible. We are testing these new methods in healthy volunteers first to understand how they work. We're looking at two main ideas: using virtual reality to create the same visual effects as the special glasses, and also trying a method where people imagine making movements without actually moving. The aim is to see if these new approaches can achieve the same helpful brain adjustments as the traditional therapy. If they do, it could open the door for people with unilateral neglect to do their therapy at home, making it much easier to continue treatment and improve their daily lives and independence.
Key takeaways
- This study explores new ways to help people with brain injuries affecting how they notice things on one side.
- It's testing virtual reality and mental imagery as possible home-based therapies.
- The study involves healthy volunteers between 18 and 70 years old.
- No medication is involved; participants will use special goggles or virtual reality.
- The goal is to develop treatments that are easier for patients to do at home.
- Your involvement could greatly help future patients improve their independence.
Who may be eligible?
This study is looking for healthy people to take part. To be considered, you need to be an adult between 18 and 70 years old. You should be right-handed, and your vision should be normal, or corrected with glasses or contact lenses (but not wearing corrective glasses during the study if those are part of the exclusion criteria).
There are also some important things that would mean you can't join the study. You cannot take part if you have any known brain or mental health conditions. If you have any problems with your right arm that would make it hard to move, you also wouldn't be able to join. Finally, if you need to wear specific corrective eyeglasses that are not allowed during the study, you also wouldn't be able to take part.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you between 18 and 70 years old?
- Are you right-handed?
- Do you have normal vision, or is it corrected (e.g., with contact lenses)?
- Do you NOT have any brain or mental health conditions?
- Do you NOT have any problems with your right arm?
- Can you participate without wearing specific corrective eyeglasses during the study?
What does participation involve?
This study involves doing various tasks using special equipment. You might wear prismatic goggles or use a virtual reality device. You'll be asked to perform activities that involve looking at things and potentially making movements or imagining them. The study is designed to understand how different ways of doing the 'prismatic adaptation' therapy work in healthy people. You won't be given any medication. The specific number of visits or total duration isn't detailed, but it will involve several assessment sessions to see the immediate and longer-term effects of the interventions. All the details about how long each session takes and how many times you'd need to come will be explained to you before you agree to take part.
Potential risks and benefits
Locations (1)
- Lyon Neuroscience Research CenterVerified postcodeBron, France· Recruiting
Common questions
What is 'unilateral neglect'?
It's a brain injury symptom where someone struggles to notice things on one side of their body or surroundings.
Why are you testing this in healthy people?
We use healthy volunteers first to understand how the new methods work in a predictable way before trying them on people with specific conditions.
What are 'prismatic goggles'?
These are special glasses that slightly shift what you see, helping your brain to adjust how it perceives space.
Will I have to take any medicine?
No, this study does not involve any medication.
Can I leave the study if I change my mind?
Yes, you can stop participating at any time without giving a reason.
How to find out more
Yves ROSSETTI, MD
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
Discussion
Community discussion
Powered by our forum at community.patient.info. Please be respectful — this is not medical advice.