REDUCE LAP-HF RANDOMIZED TRIAL I

To join this study, you would typically need to be at least 40 years old and have ongoing symptoms of heart failure. Your heart's pumping ability (called 'ejection fraction') should be 40% or higher, and you should be taking the best available heart failure medications without getting enough relief from your symptoms. Doctors will also need to confirm that you have high pressure specifically in the left side of your heart during a special exercise test.

There are also some reasons why you might not be able to join. For example, if you've recently had a heart attack, heart surgery, or a procedure to unblock arteries in the past three months. You also wouldn't be able to join if you have very severe heart failure, certain heart valve problems, or if you've had a stroke or blood clots recently. If you are on dialysis or have very poor kidney function, you would also not be eligible.

If you decide to take part in this study, you would first go through screening tests to make sure you're a good fit. If you are, you would then have a procedure to implant the small device in your heart. This involves a minimally invasive procedure, similar to a stent insertion, guided by ultrasound from inside your heart. After the procedure, you would have regular follow-up appointments with the study team. These visits would involve checks of your heart and general health, physical exams, and tests like blood pressure measurements and sometimes exercise tests. The study team will explain all the details, including the number and frequency of visits, which may span a significant period to monitor long-term effects.