Cardiac Resynchronization Therapy in Previously Untreatable and High Risk Upgrade Patients

This study is looking for adults aged 18 or over who have had heart failure for some time. You would generally be considered if your heart isn't pumping blood very well (your heart's ejection fraction is 35% or less), and you have specific electrical patterns in your heart (seen on an ECG).

Specifically, the study is for people who have struggled to get or benefit from existing heart pacing treatments. This includes individuals who attempted to have a standard CRT device but couldn't because of difficulties placing the wires, or if their existing CRT wires stopped working properly. It also includes people who might be considered at high risk for upgrading to a traditional wired system.

The detailed description of participation isn't provided in the brief summary. Typically, taking part in a study like this would involve several hospital visits for health checks, device implantation, and follow-up appointments. These appointments would likely include tests such as ECGs (heart tracings), echocardiograms (ultrasound scans of your heart), and blood tests to monitor your heart function and the device’s performance. You would also have regular check-ups to see how you are feeling and if your symptoms have improved. The total duration of participation usually involves follow-up over several months or even years. All aspects of your participation would be clearly explained by the study team, and you would have the chance to ask any questions.