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Detecting EARLY Heart Failure in Greater Manchester

This study is looking at how to find heart failure earlier in people living in Greater Manchester. At the moment, heart failure is often diagnosed quite late, especially in the North West of England, which can make it harder to treat effectively. Researchers have developed a new tool, like a special calculator, that helps identify people who are at a higher risk of developing heart failure or needing hospital care for it, even before they have official symptoms. This study will pilot this tool in local GP practices to see how well it works in a real-world setting. They want to understand if it's easy for doctors to use, whether a diverse group of people can take part, and if it could genuinely help improve early diagnosis and lead to better care for patients.

At a glance

Status
Recruiting
Sponsor
Manchester University NHS Foundation Trust
Enrolment target
600
Start
09 Oct 2023
Estimated completion
01 Sep 2030

What is this study about?

Heart failure is a serious condition where your heart can't pump enough blood around your body. It's a growing problem in the UK, and especially in the North West of England. A major challenge is that it's often diagnosed too late, making it harder to manage. This study aims to change that by finding ways to spot heart problems much earlier, potentially before people even feel unwell.

Researchers have created a special tool, a bit like a risk calculator, that can identify people who are more likely to develop heart failure or need hospital treatment for it. This tool looks at various factors, including other health conditions you might have, certain substances in your blood, and detailed scans of your heart. The idea is to find those individuals at the highest risk so that doctors can offer support or treatments *before* their condition becomes more serious.

This study is a pilot, meaning it’s a small-scale test to see how well this risk calculator works in real primary care settings, like your local GP surgery, in Greater Manchester. The researchers want to understand if the calculator is practical for doctors to use, how easy it is to involve people from different backgrounds, and how accurate it is in identifying those at risk. They will also look at the potential cost savings if heart failure can be detected and managed earlier.

Key takeaways

  • Heart failure is a growing problem, often diagnosed too late.
  • Researchers are testing a new tool to identify people at high risk of heart failure early.
  • The study aims to see how well this tool works in GP practices in Greater Manchester.
  • Early detection could lead to better management and outcomes for patients.
  • This is a pilot study focused on improving diagnosis, not on providing new treatments directly.

Who may be eligible?

This study is looking for people aged 50 or over. To be considered, you would also need to have two or more of certain health conditions. These include type 2 diabetes, a long-term lung condition like COPD, heart problems like ischaemic heart disease or atrial fibrillation, high blood pressure, moderate kidney disease, or a Body Mass Index (BMI) of 30 or more.

However, you wouldn't be able to take part if you've already been diagnosed with heart failure or certain other heart conditions like cardiomyopathy, significant problems with your heart valves, or if you've had a heart transplant. Also, if you have conditions that would make a special heart scan (called a Cardiovascular Magnetic Resonance or CMR scan) unsafe for you, such as having a pacemaker, certain metal implants, or severe claustrophobia, you wouldn't be eligible.

Finally, if your doctor thinks that participating in the study might put you at higher risk or prevent you from completing the study requirements, you might also be excluded. Pregnant or breastfeeding individuals are also not able to participate.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you 50 years old or older?
  2. Do you have two or more specific health conditions (like diabetes, COPD, high blood pressure, etc.)?
  3. Have you *not* been diagnosed with heart failure already?
  4. Do you *not* have a pacemaker, cochlear implant, or other issues preventing an MRI scan?
  5. Are you *not* currently pregnant or breastfeeding?
Answer every question to see your result.

What does participation involve?

As this is a pilot study to evaluate a risk calculator rather than an intervention, there is no direct patient participation described in the summary. The study is focused on evaluating how doctors in GP practices use the risk calculator and recruit participants for future stages. It mentions recruiting participants from primary care populations for preliminary analysis and refining the model. However, the current description does not detail what individual patient involvement would entail, such as specific visits, assessments, medication changes, or follow-up duration.

Potential risks and benefits

The main benefit of this research is the potential to improve how heart failure is detected, leading to earlier diagnosis and potentially better management for patients in the future. By identifying individuals at high risk early, doctors may be able to offer preventative strategies or treatments that could stop heart failure from developing or becoming severe. As this specific trial focuses on evaluating a risk calculator and does not involve direct intervention or new medications, the personal risks for participating would generally be very low. However, any participation in a study should always be carefully considered. You always have the right to withdraw from a study at any time without giving a reason.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • Manchester University NHS Foundation Trust
    Verified postcode
    Manchester, United Kingdom· Recruiting

Common questions

What is heart failure?

Heart failure means your heart isn't pumping blood as well as it should. It doesn't mean your heart has stopped, but it can lead to symptoms like breathlessness and tiredness.

What is a 'risk calculator'?

It's a tool that uses information about your health to estimate your chances of developing a specific condition. In this case, it helps identify people who might be at higher risk of heart failure.

Why is early detection important for heart failure?

Catching heart failure early means doctors can start treatment sooner, which can often help manage symptoms better, slow down the disease, and improve your quality of life.

Will this study offer me new treatment?

This particular study is focused on testing a new way to identify risk, not on giving new treatments directly. The hope is that improved early detection will lead to better treatment options in the future.

Who is funding this research?

The funding source is not specified in the information provided, but research studies are often funded by government bodies, charities, or sometimes pharmaceutical companies.

How to find out more

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Detecting EARLY Heart Failure in Greater Manchester…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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