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Preparatory Work for a Trial of Adjuncts to Diuretic Treatment in Patients Hospitalised With Heart Failure: Addressing Uncertainties and Building Consensus

This isn't a new treatment trial, but a very important first step to prepare for one. If you have heart failure or care for someone who does, you might be able to help. Researchers want to understand the best way to test new treatments alongside standard 'water tablets' (diuretics) for people in hospital with heart failure. They're asking heart failure patients, their carers, and healthcare professionals to share their views. This will help them decide which new treatments to test, what doses to use, and what information to collect to see if the treatments are working. Your input will help ensure the future trial is well-designed and valuable.

At a glance

Status
Recruiting
Sponsor
Hull University Teaching Hospitals NHS Trust
Enrolment target
10
Start
02 Jul 2025
Estimated completion
01 Oct 2026

What is this study about?

This project is all about getting ready for a future research study on heart failure. It's not a study where you would receive new treatments, but rather a vital preparatory stage to make sure any future trials are designed in the best possible way. The main goal is to figure out how to improve care for people who are in hospital with heart failure, specifically looking at additional treatments that could be given alongside standard 'water tablets' (diuretics).

Heart failure means your heart isn't pumping blood around your body as well as it should. This can lead to symptoms like shortness of breath and swelling. Diuretics help to remove excess fluid from your body, but researchers want to see if other treatments given at the same time could also help. Before they can run a full trial, they need to gather lots of information and opinions.

To do this, they are asking a range of people for their input. This includes doctors, nurses, and pharmacists who treat people with heart failure, as well as people who have recently been in hospital with heart failure themselves or those who care for them. By involving everyone, they hope to choose the best treatments to test, decide on the right doses, and work out what information to collect to see if the treatments are making a difference. This careful planning helps ensure future trials are successful and genuinely help patients.

Key takeaways

  • This study helps plan future heart failure research.
  • It's about finding the best way to test new treatments for heart failure.
  • Share your experiences if you've had recent heart failure or care for someone who has.
  • Your input directly shapes future trials, making them more patient-focused.
  • Participation involves online discussions, not trying new medications.

Who may be eligible?

To help with this study, you need to meet certain conditions. You must have been in hospital with heart failure yourself fairly recently (within the last six months), or you must be a carer for someone who has.

It's important that you are comfortable taking part in online group discussions and can speak English well enough to contribute effectively. This is how the researchers will gather your valuable opinions and insights.

If you find it difficult to take part in online discussions, or if English is not your main language for group conversations, then this particular part of the study might not be suitable for you.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Have I been in hospital with heart failure in the last 6 months?
  2. Or, do I care for someone who has been in hospital with heart failure recently?
  3. Am I comfortable taking part in online group discussions?
  4. Can I participate fully in online discussions in English?
Answer every question to see your result.

What does participation involve?

If you decide to take part in this preparatory study, you would primarily be involved in online group discussions. These discussions will be held in English. The aim is for you to share your experiences and opinions about hospital care for heart failure and what you think are the most important things to measure in a future trial. The study doesn't involve any medical assessments, taking new medicines, or follow-up appointments, as it's a planning stage for a future trial. The researchers will be looking for your personal insights to help shape that future study.

Potential risks and benefits

Taking part in this study offers the benefit of having your voice heard and directly influencing the design of future heart failure treatments. Your insights as a patient or carer are incredibly valuable in ensuring that future research focuses on what truly matters to those living with heart failure. There are no direct physical risks, as this study involves only discussions and no medical interventions. The main commitment is your time and willingness to share openly. You are free to withdraw from the discussions at any point without giving a reason.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • Cardiology
    Verified postcode
    Hull, United Kingdom· Recruiting

Common questions

What is heart failure?

Heart failure means your heart isn't pumping blood around your body as well as it should. It can cause symptoms like breathlessness and swelling in your legs.

Am I being asked to try a new medicine?

No, this study is not testing new medicines. It's a planning stage to help design a future study that might test new medicines. Your role is to share your experiences and ideas.

What are 'water tablets' (diuretics)?

Diuretics are medicines commonly given to people with heart failure. They help your body get rid of extra fluid, which can reduce swelling and make it easier to breathe.

How long will I need to be involved?

Your involvement would mainly be through online group discussions. The researchers will let you know the specific time commitment, but it won't be an ongoing, long-term commitment.

Will my privacy be protected?

Yes, the study will have ethical approval, meaning strict rules are followed to protect your personal information and ensure your privacy.

How to find out more

Joe Cuthbert, MBBS MD

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Preparatory Work for a Trial of Adjuncts to Diuretic Treatme…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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