OPTimising a Screening Program to Detect Pacemaker-associated Heart Failure Using Artificial Intelligence
This study aims to discover better ways to check for heart failure in people who have pacemakers. While pacemakers are crucial for many, they can sometimes lead to heart failure over time. Currently, finding this requires a long, specialised ultrasound scan of the heart, which is expensive and time-consuming. We've found that about a third of pacemaker users might have undiagnosed heart failure, and treating it early can prevent hospital stays and improve lives. This research will test two new, quicker methods: a small, hand-held ultrasound device that uses artificial intelligence (AI) to check heart function, and a simple finger-prick blood test that can show signs of heart strain. The goal is to see if these new technologies can accurately spot heart failure in people with pacemakers, making it easier and more affordable for everyone to be screened.
At a glance
What is this study about?
Pacemakers are fantastic devices that help many people whose hearts beat too slowly. They can really improve how someone feels and even save lives. However, for a small number of people, having a pacemaker can sometimes cause a type of heart problem called heart failure. This happens because the way the pacemaker makes the heart beat isn't always as natural as a healthy heart's own rhythm.
In our previous research in West Yorkshire, we found that quite a few people with pacemakers – about one in three – might have heart failure without even knowing it. The good news is, if we find this heart failure, we can treat it with safe and often inexpensive medicines. These treatments can make a big difference, helping people feel better and reducing their chances of needing to go into hospital or even saving their lives.
Right now, the best way to check for heart failure is with a special ultrasound scan of the heart, called an echocardiogram. This scan takes about 45 minutes, needs an expert technician to do it, and costs quite a bit – around £120 per scan. If we wanted to check everyone with a pacemaker at our hospital, it would cost a huge amount of money. So, we're looking for new, more efficient ways to find heart failure. This study will test two new ideas: first, we'll see if a small, hand-held ultrasound device that uses computer intelligence (AI) can check heart function just as well as the bigger, standard scan. Second, we'll check if a quick finger-prick blood test can effectively spot signs of trouble in the heart as accurately as the ultrasound.
Key takeaways
- New ways to detect heart failure in pacemaker users are being tested.
- The study compares AI-enabled hand-held ultrasound and finger-prick blood tests.
- Early detection of heart failure leads to better treatment and health.
- Current detection methods are costly and time-consuming.
- This research could make screening much easier and more affordable.
Who may be eligible?
This study is looking for adults aged 18 or older who currently have a pacemaker. For you to be considered, your pacemaker needs to be working in a specific way that causes a certain amount of stimulation to your heart's right ventricle (this is something your doctor can tell you).
There are some reasons why you might not be able to join. For example, if you already know you have heart failure, or if past heart scans showed your heart wasn't pumping strongly enough, this study might not be for you. Also, if you have certain types of pacemakers, like those used for cardiac resynchronisation therapy or leadless pacemakers, you won't be able to participate. This is because these pacemakers work differently, and the study focuses on a specific type of heart problem linked to standard pacemakers.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you 18 years old or older?
- Do you currently have a pacemaker?
- Has your doctor confirmed that your pacemaker provides a specific type of pacing to your right ventricle?
- Do you NOT already know you have heart failure?
- Have you NOT had previous scans showing your heart pumping weakly?
- Do you NOT have a specialised pacemaker (like a CRT or leadless pacemaker)?
What does participation involve?
The detailed involvement for participants isn't fully described in the summary, but based on the two approaches described: you would likely have a hand-held heart ultrasound scan done using AI technology, and a finger-prick blood test. These tests would probably happen during a routine appointment or special study visit. The study aims to compare these new methods to the standard ultrasound scan, so you might also have a standard echocardiogram. The total duration and number of visits are not specified, but the new tests are designed to be quick.
Potential risks and benefits
Locations (1)
- Cardiovascular Research Facility, Leeds General InfirmaryVerified postcodeLeeds, United Kingdom
Common questions
What is heart failure?
Heart failure means your heart isn't pumping blood around your body as well as it should. It doesn't mean your heart has stopped working, but it can make you feel tired and breathless.
Why would my pacemaker cause heart failure?
While pacemakers are very helpful, sometimes the way they make your heart beat can, over many years, put an unusual strain on the heart muscle for some people.
What is an echocardiogram?
An echocardiogram is a type of ultrasound scan that uses sound waves to create a moving picture of your heart. It helps doctors see how well your heart is pumping.
What is AI?
AI stands for Artificial Intelligence. In this study, it means computer programs that can help read the hand-held ultrasound scans to make them more accurate and quicker.
Is the finger-prick blood test painful?
A finger-prick blood test is usually a very quick and minor discomfort, similar to a pinprick, to get a small drop of blood.
How to find out more
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
Discussion
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