RecruitingOBSERVATIONAL

Prospective Hyperthermia Database in Cancer Patients (HT Register)

This study, called the Hyperthermia Register, is collecting information from cancer patients receiving hyperthermia treatment at Charité hospital. Hyperthermia is a treatment that uses heat to damage cancer cells. The main goal is to understand how effective hyperthermia is when used alongside standard cancer treatments like chemotherapy or radiotherapy, and to identify any potential risks or benefits. The researchers will follow patients over time to track their health, how their cancer responds, and if they experience any side effects. There's also an option to take part in extra research that looks for factors that predict how well someone might respond to hyperthermia treatment.

At a glance

Status

Recruiting

Sponsor

Pirus Ghadjar

Enrolment target

1,000

Start

01 Nov 2014

Estimated completion

31 Oct 2028

Hyperthermia Cancer

What is this study about?

This study, called the Hyperthermia Register, is set up at the Charité hospital to learn more about how hyperthermia treatment works for people with cancer. Hyperthermia is a treatment where part of the body, or sometimes the whole body, is heated. It's often used alongside other cancer treatments like chemotherapy (drug treatment), radiotherapy (radiation treatment), or a combination of both.

The main idea behind this study is to gather information from many patients to get a clearer picture of how beneficial hyperthermia is in general, and what the potential risks might be. The researchers want to track patients over time to see how their cancer responds to treatment and if they have any side effects. This helps them understand the overall balance of benefits versus risks for patients receiving hyperthermia. It’s like keeping a detailed diary for many patients to see common patterns and outcomes.

As part of this study, there's also an opportunity to take part in some optional extra research. This additional research aims to find specific things (called 'prognostic factors') that might help predict how well a patient will respond to hyperthermia. This could help doctors in the future to know which patients might benefit most from this treatment.

Key takeaways

This study collects real-world data on hyperthermia cancer treatment.
It aims to understand benefits and risks of hyperthermia.
Patients' health and treatment outcomes are tracked over time.
No new treatments are given as part of this study.
Your participation helps improve future cancer care for others.

Who may be eligible?

This study is looking to include around 1,000 patients who are receiving hyperthermia treatment alongside their standard cancer care, which might include radiotherapy, chemotherapy, or both. Patients could have different types of cancer, as long as hyperthermia is a suitable part of their treatment plan.

To join, adult patients need to understand the study and provide their written consent. For children, the treatment must follow specific guidelines agreed upon by a group of children's cancer specialists (GPOH).

However, some things might mean you can't take part. For example, if you have certain metal implants in your body (like some hip replacements or pacemakers) or certain mental health conditions that would make it hard to understand or take part in the study properly, you might not be eligible. If you're already in another research study, you might still be able to join this Register, as long as the other study allows it.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you a cancer patient receiving hyperthermia treatment at Charité hospital?
Can you understand the study information and provide written consent?
Do you not have metal implants (like pacemakers or some hip replacements) in the area to be treated?
Do you feel you can properly take part in the study and understand what's involved?
If female and of child-bearing age, are you using contraception?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, the main thing you'll be doing is letting the hospital collect information about your hyperthermia treatment and your health over time. This includes information about your cancer, how it responds to treatment, and any side effects you might experience. This information will be collected from your routine medical appointments and records, so you won't need extra hospital visits just for the study.

The researchers will follow your progress into the future to see how your condition changes and how you're doing after treatment. There's also an optional part of the study where you could contribute to additional research aimed at understanding why some people respond better to hyperthermia than others. The total duration of your participation will depend on your treatment journey and how long the researchers need to follow your health status.

Potential risks and benefits

The main benefit of taking part in this study is that you would be contributing to a better understanding of hyperthermia treatment for cancer patients. This could help improve how doctors use hyperthermia in the future, making it more effective and safer for others. As this is mainly a registration study, collecting information from your existing treatment, there are generally no additional direct medical risks beyond those already associated with your hyperthermia and standard cancer treatments. You are free to withdraw from the study at any time, for any reason, without affecting your medical care.

Locations (2)

Clinic for Radio - Oncology and Radiotherapy
Verified postcode
Berlin, Germany· Not yet recruiting
Clinic for Radio - Oncology and Radiotherapy
Verified postcode
Berlin, Germany· Recruiting

Common questions

What is hyperthermia treatment?

Hyperthermia is a type of cancer treatment that uses heat to damage and kill cancer cells. It's often used with other treatments like chemotherapy or radiotherapy.

Do I get any new treatment by joining this study?

No, this study is about gathering information on hyperthermia when it's used as part of your existing treatment plan. You won't receive extra or different treatments just for the study.

What kind of information will be collected about me?

The study will collect information about your cancer, the hyperthermia treatment you receive, how you respond to treatment, and any side effects you might have. This comes from your routine medical records.

Can I leave the study if I change my mind?

Yes, you can choose to leave the study at any point, for any reason, without it affecting your medical care or your relationship with your doctors.

Will my personal details be kept private?

Yes, all your personal information collected for the study will be kept confidential and handled according to strict privacy rules.

How to find out more

Pirus Ghadjar, PD Dr.

pirus.ghadjar@charite.de +4930450657055 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.