RecruitingNAINTERVENTIONAL

Clinico-biological Data Collection Study of Metastatic Lung Cancer

This study is collecting detailed information from people with advanced lung cancer. The main goal is to better understand why some treatments are successful for certain people, while for others, they might not work as well. We'll be looking at many different factors, including your medical history, how you feel psychologically and emotionally, your social situation, and specific details about your tumour. By gathering all this information, researchers hope to create new tools that can help predict which treatments are most likely to be effective for individual patients. This could lead to more personalised and successful treatment plans for everyone with advanced lung cancer in the future.

At a glance

Status

Recruiting

Phase

Sponsor

Institut Cancerologie de l'Ouest

Enrolment target

200

Start

24 Apr 2023

Estimated completion

01 Oct 2031

Lung Cancer

What is this study about?

This study is about understanding advanced lung cancer better. When cancer spreads, it's called metastatic lung cancer. Doctors use different treatments, but it's not always clear why they work well for some people and not for others. This can be very frustrating for patients and their families, and doctors are always looking for ways to improve.

Researchers believe that many factors play a part in how a person responds to treatment. These can include things like the specific type of lung cancer, details about the tumour itself, but also a person's general health, their feelings, and even their daily life. By collecting all these different types of information, doctors hope to get a complete picture of what influences treatment success.

The main aim is to build a large database with all this information. This database will help researchers develop new tools and ways of thinking about how to treat lung cancer. They want to be able to predict more accurately which treatments will work best for each individual person. This could lead to more effective and personalised care in the future, meaning patients get the right treatment for them, sooner.

Key takeaways

Study focuses on advanced lung cancer.
Aims to understand why treatments work differently for people.
Collects detailed health, lifestyle, and tumour information.
Future goal: develop tools to predict best treatments.
Your treatment will be standard medical care, not experimental.
You can stop participating at any time.

Who may be eligible?

To take part in this study, you need to be at least 18 years old and have lung cancer that has spread (metastatic) or is locally advanced and can't be cured with local treatments. You should also be well enough to carry out most of your daily activities.

It's important that you're willing to follow the study plan, including attending appointments and having any necessary tests. You also need to be covered by a social health insurance plan. If you agree to take part, you'll be asked to sign a consent form, which means you understand what the study involves.

You won't be able to join if you've had another type of cancer treated in the last three years (unless it was a common skin cancer or a specific type of cervical cancer). Also, if you are pregnant or breastfeeding, have certain other rare tumour types, or if personal circumstances would make it very difficult to attend your study appointments, you might not be suitable for this research.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Do you have lung cancer that has spread (metastatic) or is locally advanced?
Are you generally well enough to go about most of your daily activities?
Are you willing to attend appointments for tests and follow-up?
Do you not have another type of cancer (except certain skin or cervical cancers) treated in the last 3 years?
Are you not pregnant or breastfeeding?

Answer every question to see your result.

What does participation involve?

If you decide to take part, you would first give your written consent. This study involves collecting information and samples related to your advanced lung cancer. You will have a biopsy (a small tissue sample taken) from your metastatic tumour or lung if the cancer has come back locally. Blood samples will also be taken during your regular medical care. You will also be asked to complete questionnaires about your health, feelings, and social situation. The treatments you receive will be part of your usual care, guided by what your doctors recommend, and will follow national and international guidelines. This study will simply be collecting information about those treatments and your progress. You will have scheduled visits and examinations, similar to your routine check-ups, and the study will follow your progress for an ongoing period.

Potential risks and benefits

Taking part in this study could help doctors understand more about advanced lung cancer, which may lead to better treatments for future patients. While you might not directly benefit from the information collected, you will receive all standard medical care and monitoring. The main risks involve the usual procedures like biopsies and blood tests, which can have minor side effects such as bruising or discomfort. You are free to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (2)

Institut de Cancerologie de L'Ouest
Verified postcode
Angers, France· Recruiting
Institut de Cancerologie de L'Ouest
Verified postcode
Saint-Herblain, France· Recruiting

Common questions

What kind of cancer are you studying?

We are studying advanced lung cancer that has spread to other parts of the body (metastatic) or is locally advanced.

What information will the study collect about me?

We'll collect information about your medical history, your feelings and mental well-being, your social life, imaging scans, and details about your tumour from biopsies and blood tests.

Will I get new medicines if I join this study?

No, this study doesn't involve new medicines. You will receive the standard treatments that your doctors recommend for your type of lung cancer.

How long will I be in the study?

The study will follow your progress on an ongoing basis as part of your regular medical care.

Will this study help me personally?

While this study won't offer a direct personal benefit today, the information gathered will help doctors better understand lung cancer and could lead to improved treatments for future patients.

How to find out more

JUDITH RAIMBOURG, MD,PHD

judith.raimbourg@ico.unicancer.fr 0240679900 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.