RecruitingOBSERVATIONAL

American Hepato-Pancreato-Biliary Association (AHPBA) Pancreatic Irreversible Electroporation (IRE) Registry

This study is setting up a registry, which is like a central database, for people in the UK with pancreatic cancer who are having a treatment called Irreversible Electroporation (IRE). The main goal is to collect information on how doctors choose this treatment and how patients get on with it. This will help build a strong understanding of IRE, so medical professionals can provide the best possible care. They also want to learn about any problems or concerns doctors and patients might have had with this treatment in the past. This isn't a new drug trial; it's about observing and recording real-world experiences with an existing procedure.

At a glance

Status

Recruiting

Sponsor

University of Louisville

Enrolment target

500

Start

01 Jan 2016

Estimated completion

01 Jan 2030

Pancreatic Cancer

What is this study about?

Imagine a hospital where doctors are trying a new way to treat pancreatic cancer, but they want to make sure they're giving the best possible care. This study, led by a group called the American Hepato-Pancreato-Biliary Association (AHPBA), is creating a big online database, called a registry. Think of it like a carefully organised collection of notes about patients who have a treatment called Irreversible Electroporation, or IRE, for their pancreatic cancer. The main aim is to understand how and when doctors decide to use IRE and how it works out for patients.

By gathering all this information in one place, doctors can learn from each other's experiences. This helps them improve the treatment choices they offer and aim for the best results for people with pancreatic cancer. It's especially focused on understanding IRE for pancreatic tumours that can't be removed by surgery and to discover any problems or difficulties that have come up with this treatment before.

This isn't about testing a new medicine or a completely new procedure. Instead, it's about carefully watching and recording what happens when people receive IRE, a treatment that's already in use. The information gathered will be used to make sure doctors are providing the best care possible to patients needing surgery for pancreatic cancer.

Key takeaways

The study is creating a database (registry) about IRE treatment for pancreatic cancer.
It aims to improve doctors' understanding of IRE and patient care.
No new treatments or extra appointments are involved for participants.
It focuses on learning from real-world experiences with IRE.
Information collected will help future patients with pancreatic cancer.

Who may be eligible?

To be able to take part in this registry, you need to be an adult (18 years or older) and have been diagnosed with pancreatic cancer. Your doctor would also need to have decided that a specific treatment called soft tissue ablation, which includes IRE, is suitable for you.

There are also some important reasons why you might not be able to be included. For example, if you have a heart pacemaker or a special heart device called an ICD, this study wouldn't be right for you. Also, if you have any metal implants that can't be removed near where the treatment would be given, or if you've had a heart attack in the last three months, you wouldn't be able to join. Finally, if you're not well enough to have a general anaesthetic, which is often needed for this kind of treatment, you wouldn't be eligible.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Have you been diagnosed with pancreatic cancer?
Is your doctor considering (or have you had) IRE or a similar 'ablation' treatment?
Do you NOT have a heart pacemaker or an ICD device?
Have you NOT had a heart attack in the last 3 months?

Answer every question to see your result.

What does participation involve?

If you are eligible and agree to be part of this registry, it means your medical information related to your pancreatic cancer and IRE treatment will be collected and shared with the study organisers. This doesn't involve any extra hospital visits, new medications, or follow-up appointments beyond what your doctor would normally recommend for your care. The study simply collects information from your existing medical records over time to see how the treatment progresses and how you get on. There's no set end date for your participation, as data will be collected as part of your ongoing care.

Potential risks and benefits

Taking part in this registry doesn't directly offer a personal medical benefit, as it's about collecting information, not providing treatment. However, the information gathered will help future patients by improving our understanding of IRE and leading to better care. There are no additional risks to your health by simply having your data included. You have the right to withdraw your consent for your information to be used at any time, without affecting your medical care.

Locations (16)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

University of Alabama Birmingham
Verified postcode
Birmingham, United States· Recruiting
University of California San Diego
Verified postcode
San Diego, United States· Recruiting
University of Colorado
Verified postcode
Denver, United States· Recruiting
University of South Florida
Verified postcode
Tampa, United States· Recruiting
Augusta University
Verified postcode
Augusta, United States· Recruiting
University of Louisville
Verified postcode
Louisville, United States· Recruiting
Johns Hopkins Hospital
Verified postcode
Baltimore, United States· Recruiting
Atlantic Health
Verified postcode
Millburn, United States· Recruiting
Northwell Health Cancer Institute
Verified postcode
Lake Success, United States· Recruiting
Gibbs Cancer Research, Spartanburg Regional Healthcare System
Verified postcode
Spartanburg, United States· Recruiting
Methodist Digestive Institute
Verified postcode
Dallas, United States· Recruiting
McGill University
Verified postcode
Montreal, Canada· Recruiting

Common questions

What is a 'registry' in this study?

A registry is a secure collection of medical information from many patients, used to learn more about a disease or treatment over time.

Will I receive any new treatments in this study?

No, this study is not a clinical trial testing new treatments. It's about collecting information on a treatment (IRE) you're already receiving as part of your standard care.

Who will see my personal information?

Your personal details will be kept confidential. Researchers will mainly look at anonymised data, meaning information is used without directly identifying you.

What is the goal of this study?

The main goal is to help doctors better understand IRE treatment for pancreatic cancer, leading to improved care for patients in the future.

Do I have to take part?

No, taking part is completely voluntary. Your decision will not affect your medical care in any way.

How to find out more

Robert Martin, MD, PhD

robert.martin@louisville.edu 502-629-3355 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.