Mobilise-D: Extension Study
This study, called Mobilise-D, is an extension of a previous project. It aims to understand how Parkinson's disease (PD) affects movement over time and how natural aging changes our mobility. Researchers will use a small device worn on the body to track movement in people with PD and in healthy individuals of a similar age. By comparing these groups, they hope to get a clearer picture of PD progression and the effects of aging. The information gathered could help develop better ways to monitor PD and everyday mobility, potentially leading to improved care in the future.
At a glance
What is this study about?
This study, called the Mobilise-D Extension Study, is all about understanding how our ability to move changes, especially for people living with Parkinson's disease (PD). It builds on a previous study and aims to gather more information over a longer period.
The main idea is to see how a special device that you wear on your body can help measure and understand movement in people with PD. By tracking everyday movements, researchers hope to get a clearer picture of how PD progresses. They also want to understand how movement naturally changes as we get older by comparing people with PD to healthy individuals of a similar age.
The information collected from this study is really important. It will help researchers learn more about PD and how it affects daily life. Ultimately, this could lead to better ways for doctors to monitor the condition and help people manage their symptoms more effectively.
Key takeaways
- A study to understand Parkinson's disease progression and normal aging effects on movement.
- Uses a small, body-worn sensor to track everyday movements.
- Compares people with Parkinson's and healthy individuals.
- Participation involves clinic visits and wearing a sensor for 7 days.
- Information gathered will help develop better ways to monitor mobility and Parkinson's.
- You can stop participating at any time without affecting your medical care.
Who may be eligible?
To join this study, we're looking for two main groups of people. Firstly, if you've already taken part in the previous Mobilise-D Clinical Validation Study as a Parkinson's patient, you might be invited to join this extension.
Secondly, we're looking for healthy volunteers aged 50 or over. You should be able to walk a short distance (4 metres) without help and be available to take part for about a year. You also need to be able to read and write in your local language and be willing to wear a small sensor device for monitoring your movement.
There are certain health conditions or past medical events that would mean you couldn't take part. For example, if you've recently had a heart attack, stroke, or certain heart surgeries, or if you have specific long-term conditions like severe heart failure, certain neurological or orthopaedic problems affecting your walking, or a diagnosis of dementia or Parkinson's disease. We also can't include people with other movement disorders or certain lung conditions like COPD.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you aged 50 or over (for healthy volunteers)?
- Can you walk a short distance (4 metres) without help?
- Are you able to spare time for study visits over about a year (for healthy volunteers)?
- Are you willing to wear a small body sensor for one week?
- Do you have a clear understanding of what's involved and can give your consent?
- Have you checked you do not have any of the listed conditions that would exclude you?
What does participation involve?
If you decide to take part, what you'll be asked to do depends on whether you have Parkinson's disease or are a healthy volunteer. If you have Parkinson's and were part of the previous study, you'll need to attend one follow-up visit about three years after your initial visit. If you're a healthy volunteer, you'll have a first visit and then another follow-up visit about 12 months later.
During each visit, you'll have some checks, answer questions about your health and daily life, and do some physical and memory tests. After each visit, you'll be asked to wear a small sensor on your body for seven days continuously to track your movement. It's a bit like a fitness tracker but designed for research.
A small number of participants will also be invited to have a chat (an interview) with the research team. This is a chance to talk about your experiences with Parkinson's symptoms and how they affect your movement. These interviews can be in person or online, whatever works best for you.
Potential risks and benefits
Locations (1)
- The Newcastle upon Tyne Hospitals NHS Foundation TrustVerified postcodeNewcastle upon Tyne, United Kingdom· Recruiting
Common questions
What is the purpose of wearing a sensor?
The sensor helps researchers accurately track your everyday movements in your natural environment, giving a better picture than relying only on tests done in a clinic.
Do I need to change my medication for this study?
No, this study is 'observational', meaning we simply learn from how you live your life. You will not be asked to change any medications.
How long will I need to be involved?
If you have Parkinson's and were in the previous study, you'll have one follow-up visit. If you're a new healthy volunteer, you'll have two visits over about 12 months.
Will I get results from the study?
You won't receive individual results, but the overall findings will help inform future understanding and care for Parkinson's disease and aging.
What if I decide I don't want to continue?
You are absolutely free to withdraw from the study at any time, for any reason, without needing to explain why, and it won't affect your medical care.
How to find out more
Isabel K Neatrour, MSc
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
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