The COSP-RBD Study: Concussions and Contact Sports in RBD vs Controls
This study is investigating a sleep condition called REM sleep behaviour disorder (RBD), where people act out their dreams during sleep. We know that RBD can sometimes be an early sign of other brain conditions like Parkinson's disease. We also know that repeated concussions or head injuries can increase the risk of developing brain problems later in life. This research aims to understand if there is a connection between having had concussions or playing contact sports and developing RBD. Researchers will compare people with RBD to a similar group of people without RBD, asking them about their history of concussions and participation in contact sports, to see if these experiences are more common in those with RBD.
At a glance
What is this study about?
This research is looking into a sleep problem called REM sleep behaviour disorder, or RBD for short. People with RBD often act out their dreams, sometimes quite vividly, while they're asleep. It's important to study RBD because, for many people, it can be an early sign that they might develop other serious brain conditions later on, like Parkinson's disease or certain types of dementia. Understanding what might be linked to RBD could help doctors identify it earlier, which could be really important if new treatments become available in the future to protect the brain.
We already know from other research that having repeated concussions or head injuries can increase someone's risk of developing brain conditions like Parkinson's disease. Some past studies have also suggested that people with RBD might report having had more head injuries than those without the condition. This particular study wants to carefully check if that connection is true here in the UK, and to see if playing contact sports might also be a factor.
To do this, the researchers will talk to two groups of people: one group who has been diagnosed with RBD and another group without RBD. They will ask everyone about their history of concussions and whether they've played contact sports. By comparing the answers from these two groups, the study hopes to find out if there's a stronger link between concussions, contact sports, and RBD.
Key takeaways
- This study explores a possible link between concussions/contact sports and REM sleep behaviour disorder (RBD).
- Researchers want to see if a history of concussions is more common in people with RBD.
- Participation involves an interview about your past head injuries and sports.
- No new medications or treatments are involved.
- The study aims to help understand RBD and potential early identifiers for brain conditions.
- Your contribution could lead to better future understanding and care.
Who may be eligible?
To join this study, you need to be aged 50 or older. There are two main groups of people they are looking for: those with diagnosed REM sleep behaviour disorder (RBD) and those without it.
If you have RBD, you must have been diagnosed at Guy's and St Thomas' NHS Foundation Trust. If you don't have RBD, you would also need to have undergone a sleep study (called a v-PSG) at Guy's and St Thomas' NHS Foundation Trust and not have any signs of RBD or other serious brain conditions. You also need to be able to understand and speak English.
People under 50, or those with certain other conditions like narcolepsy, post-traumatic stress disorder, or other significant brain problems, won't be able to take part in this study.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you 50 years old or older?
- Do you have a confirmed diagnosis of REM sleep behaviour disorder (RBD) from Guy's and St Thomas' NHS Foundation Trust?
- OR, have you had a sleep study (v-PSG) at Guy's and St Thomas' NHS Foundation Trust and do not have RBD or other serious brain conditions?
- Can you speak and understand English?
- Do you not have conditions like narcolepsy or post-traumatic stress disorder?
What does participation involve?
If you decide to take part, you will have an interview with a specialist doctor who focuses on sleep problems. This interview will involve answering questions mainly about any concussions you may have had in the past and whether you have played contact sports like rugby or boxing. There are no medications to take, no extra visits, and no follow-up appointments required for this study. Your participation will involve just this one interview.
Potential risks and benefits
Locations (1)
- Guy's & St Thomas' NHS Foundation TrustVerified postcodeLondon, United Kingdom· Recruiting
Common questions
What is REM sleep behaviour disorder (RBD)?
RBD is a sleep problem where you act out vivid dreams during sleep, sometimes by shouting, punching, or kicking.
What is a concussion?
A concussion is a type of mild brain injury caused by a bump, blow, or jolt to the head or body.
Do I need to take any medicine for this study?
No, this study does not involve taking any medicine or trying new treatments.
How long will taking part in the study take?
Your involvement will be a single interview with a sleep specialist.
Will my regular medical care be affected if I join?
No, taking part in this study will not affect your usual medical care in any way.
How to find out more
Laura Pérez-Carbonell, PhD
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
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