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RecruitingNAINTERVENTIONAL

Neural Mechanisms of Music Intervention Chronic Arm Hemiparesis Following Stroke: A Single Case Series EEG Study

This study is exploring how playing music could help people who have had a stroke to regain movement in their arm. Many people experience weakness or difficulty moving one side of their body after a stroke, a condition called hemiparesis. Researchers want to understand if a special kind of music therapy, called Therapeutic Instrumental Music Performance (TIMP), can help the brain rewire itself (neuroplasticity) and improve arm and hand function. Five volunteers will take part in a three-week programme of music therapy sessions at home. Trained therapists will guide them in playing various instruments, including percussion and touchscreen devices, designed to encourage arm and finger movements. Throughout the study, participants will have brainwave tests (EEGs) and assessments to measure changes in their arm movement and quality of life.

At a glance

Status
Recruiting
Phase
NA
Sponsor
Anglia Ruskin University
Enrolment target
5
Start
01 Jul 2024
Estimated completion
01 May 2025

What is this study about?

Imagine learning to play an instrument, like a drum or a keyboard, to help your arm recover after a stroke. That's exactly what this study is exploring! After a stroke, people often find it hard to move one side of their body, especially an arm or hand. This study, led by researchers, wants to see if a special type of music therapy can help make those movements easier and improve how people use their arm in daily life. They're particularly interested in understanding if music therapy can help the brain create new connections and pathways, which is like the brain 'rewiring' itself.

To find out, a small group of five volunteers will take part in a three-week music therapy programme in their own homes. During these sessions, trained therapists, including music therapists and stroke rehabilitation specialists, will guide participants in playing various instruments. These might include drums, other percussion instruments, or even interactive apps on an iPad that simulate keyboards or string instruments. The activities are designed to encourage a wide range of arm, hand, and finger movements, similar to those needed for everyday tasks. The aim is to make the exercises more challenging as participants improve, without overstraining.

The researchers will measure changes in the brain using a test called an electroencephalogram (EEG), which records electrical activity in the brain. They'll do this before and after the music therapy to see if there are any changes in brain activity related to recovery. They will also carry out practical tests to assess how well participants can move their arm and hand, and ask questions about their quality of life, both before and at different points after the music therapy. This will help them understand if the therapy truly makes a difference to people's lives and their ability to use their arm.

Key takeaways

  • This study explores music's role in stroke arm recovery.
  • It involves home-based music therapy sessions.
  • Brain activity (EEG) and arm movement will be measured.
  • Participation lasts about 10 weeks, including follow-ups.
  • It could help improve arm function and quality of life.

Who may be eligible?

You wouldn't be able to join if your stroke was caused by bleeding in the brain (a haemorrhagic stroke), or if you can't move your arm at all, or if you can't move your thumb and at least one other finger. People who are currently having music therapy, are left-handed, or are able to use both hands equally well (ambidextrous) also can't take part. Lastly, if you are unable to give consent or are not registered with a GP, you wouldn't be eligible.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you 18 years or older?
  2. Did you have an ischaemic stroke (not a bleed)?
  3. Was your stroke between 3 weeks and 5 years ago?
  4. Can you move your arm a little bit and wiggle your thumb and at least one other finger?
  5. Are you right-handed?
  6. Are you able to understand and agree to take part?
Answer every question to see your result.

What does participation involve?

If you decide to take part, a clinician will first tell you about the study. If you're interested, the research team will contact you to discuss it further and help you understand the consent process. Once you're officially in the study, a researcher will visit your home to carry out some initial tests on your arm and hand movement, and ask you to fill out a questionnaire about your quality of life.

Following these initial checks, you'll have 15 music therapy sessions over three weeks, all conducted in your home by trained therapists. These sessions will use instruments like percussion, an iPad, and a guitar. Before and after these sessions, you'll have special brain scans (EEGs) at a lab. You'll also have follow-up assessments in your home at weeks 1, 4, 7, and 10 after starting the study to check your arm function and quality of life. You'll be asked to keep a log of your activities during the study. The total duration of active participation, including follow-up, is about 10 weeks.

Potential risks and benefits

Taking part in this study could potentially help improve movement in your arm and hand, and possibly enhance your quality of life after a stroke. It also contributes to important research that might help countless other stroke survivors in the future. As with any activity, there's a small chance of minor discomfort during the exercises, but the therapists are trained to guide you safely. EEG tests are generally very safe and non-invasive. You have the right to withdraw from the study at any time, for any reason, without it affecting your usual medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • Cambridgeshire COmmunity Services NHS Trust
    Verified postcode
    Bedford, United Kingdom· Recruiting

Common questions

What kind of music instruments will I be playing?

You might play various percussion instruments, or use an iPad with touchscreen instruments like keyboards or string instruments.

How long do the music therapy sessions last each day?

Details on the length of individual sessions aren't specified here, but you will have 15 sessions over three weeks.

Do I need to be able to play a musical instrument already?

No, you don't need any musical experience. The therapy is about movement and brain activity, not musical skill.

What is an EEG test?

An EEG is a simple and painless test that measures the electrical activity in your brain. Small sensors are placed on your scalp.

Will I have to travel for the study?

Most sessions and assessments will be in your home. You will need to travel to a lab for the EEG recordings.

How to find out more

Alexander J Street, PhD

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Neural Mechanisms of Music Intervention Chronic Arm Hemipare…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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