RecruitingOBSERVATIONAL

Post-Operative Myocardial Incident & Atrial Fibrillation

This study aims to understand why some people experience serious heart problems, like a heart attack (myocardial incident) or an irregular heartbeat (atrial fibrillation), after an operation on their heart or a procedure to replace a heart valve. It's for adults, male or female, aged 18 and over, who are having either heart bypass surgery, valve surgery, or a transcatheter valve replacement. Researchers are particularly interested in seeing if factors related to your white blood cells, body fat, or the way your heart works before surgery can predict these future heart issues. By understanding these links better, doctors hope to improve care for patients undergoing heart procedures.

At a glance

Status

Recruiting

Sponsor

University Hospital, Lille

Enrolment target

1,500

Start

30 Jan 2018

Estimated completion

01 Jan 2028

Valve Heart Disease Coronary Artery Disease

What is this study about?

This research study is all about helping people who are having heart surgery or a keyhole procedure to replace a heart valve. We know that sometimes, after these important treatments, a small number of people can experience unexpected heart problems, like a heart attack or a common type of irregular heartbeat called atrial fibrillation. The main goal of this study is to look closely at why these things happen, so doctors can better understand and hopefully prevent them in the future.

Imagine we're looking for clues. The researchers are particularly interested in seeing if there are any signs or "predictors" in your body *before* your operation that might suggest you're more likely to have one of these heart problems afterwards. They will be looking at things like certain cells in your blood (called leukocytes), how your body handles fat, and various details about your heart's health. By carefully studying these aspects, they hope to unlock secrets about the mechanisms – the biological ways – these issues develop.

Ultimately, this research matters because it could lead to better ways to identify patients who might be at higher risk and, most importantly, to develop improved ways to look after them. The hope is that by understanding these connections, we can make heart surgeries and valve procedures even safer and more successful for everyone.

Key takeaways

Aims to understand why heart problems happen after heart surgery.
For adults having heart bypass or valve operations.
No new medications are given as part of the study.
Researchers will look at blood, fat, and heart details before surgery.
Hopes to improve future care for heart patients.

Who may be eligible?

This study is looking for adult patients who are planning to have certain heart treatments. This includes people who are scheduled for heart bypass surgery, an operation to fix or replace a heart valve, or a keyhole procedure to replace a heart valve (which is called a transcatheter valve implantation).

There are a few reasons why someone might not be able to join. For example, if you are pregnant, you won't be able to take part. Also, if your surgery is an emergency operation, rather than one planned in advance, then this study isn't suitable for you.

Finally, it's very important that everyone who takes part fully understands what the study involves and is able to agree to it themselves. If for any reason someone isn't able to give their consent, they wouldn't be able to join the study.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

I am 18 years old or older.
I am having planned heart bypass surgery, valve surgery, or a keyhole valve replacement.
I am not pregnant.
My surgery is not an urgent, emergency operation.
I can understand and agree to take part in the study myself.

Answer every question to see your result.

What does participation involve?

The detailed involvement for this study isn't fully described, but generally, studies like this often involve researchers collecting information and samples during your routine hospital visits for your heart surgery or valve procedure. This might include collecting extra blood samples, or using information from your medical tests and records before and after your operation. There won't be any new medication given as part of this study, as it's focused on understanding existing conditions and outcomes. Any follow-up would likely be linked to your standard post-operative care. The total duration of your involvement isn't specified but typically covers the period around your surgery and recovery.

Potential risks and benefits

Taking part in this study could potentially help doctors understand heart problems better in the future, which could lead to improved care for patients like you. There are no direct benefits to you as an individual, as it's a study aiming to learn more. The risks involved are generally low, mainly related to any additional blood samples collected, which carries a small risk of bruising or discomfort. You always have the right to change your mind and withdraw from the study at any time without it affecting your medical care.

Locations (1)

Hôpital Cardiologie, CHU
Verified postcode
Lille, France· Recruiting

Common questions

What kind of heart problems is the study looking at?

It's looking at heart attacks and an irregular heartbeat called atrial fibrillation that can happen after heart surgery.

Do I have to take any new medicine for this study?

No, this study does not involve giving you any new medication. It's about gathering information.

Who can join this study?

Adults aged 18 and over who are having heart bypass surgery, valve surgery, or a keyhole valve replacement.

What won't I have to do if I join?

This study doesn't require extra hospital visits or special tests beyond your usual medical care.

Can I leave the study if I change my mind?

Yes, you can withdraw from the study at any time, and it won't affect your treatment or care.

How to find out more

David Montaigne, Prof.

david.montaigne@chru-lille.fr 320445230 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.