- completed
Reducing the impact of diabetic foot ulcers on patients and the NHS
Diabetic foot ulcers can be painful and slow to heal. The REDUCE study tests a new support programme with a healthcare professional and website to help prevent ulcers coming back. Adults with diabetes whose foot ulcers have recently healed can join to help improve future NHS care.
United Kingdom · England - completedNot Applicable
Blood glucose performance test
This study checks how accurately everyday blood glucose monitors work for people with diabetes. Researchers compare readings from regular finger-prick kits against high-precision laboratory machines. Taking part involves a single, short hospital visit of 5 to 20 minutes to give a small blood sample from a finger-prick or vein.
United Kingdom · England - authorisedTherapeutic use (Phase IV)
Do GLP-1 based therapies improve the immunological response to vaccination in diabetes?
This study looks at whether a diabetes medicine called Victoza helps the immune system build stronger defences after a pneumonia vaccine. Researchers want to see if the medicine increases protective antibodies in adults with diabetes, helping them fight off chest infections more effectively over four months.
Netherlands - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Randomised, crossover bioequivalence clinical trial of linagliptin/metformin 2.5 mg/1000 mg film-coated tablets, after a single oral dose administration to healthy volunteers under fed conditions.
This study is testing a new version of a common diabetes medicine, linagliptin/metformin. It wants to see if the new tablet works the same way in healthy adults as the original medicine, after they've eaten. This helps make sure new medicines are just as good.
Spain - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence clinical trial of dapagliflozin 10 mg tablets, after a single oral dose administration to healthy volunteers under fasting conditions.
This study is checking if a new version of a common diabetes medicine, dapagliflozin, works the same way in your body as the original. It involves healthy adults taking a single dose to see how it's absorbed.
Spain - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
An open label, balanced, randomized, single dose, two treatment, two period, two sequence, crossover, bioequivalence study comparing Empagliflozin Tablets 25 mg, manufactured by Sun Pharmaceutical Industries Limited, India with Jardiance (Empagliflozin) 25 mg film-coated tablets, Marketing Authorisation Holder Boehringer Ingelheim International GmbH Binger Strasse 173 55216 Ingelheim am Rhein Germany, in healthy adult, human subjects under fasting condition.
This study is comparing two different versions of a diabetes medicine called Empagliflozin. We want to see if a new version works the same as the original. Healthy adults will be given one dose and carefully checked.
Romania - completed
The intelligent Diabetes Platform - iDiabetes
The iDiabetes study tests a smart computer tool to help NHS doctors give personalised diabetes care. By looking closely at your routine health records and blood test results, the tool suggests the best treatments for you. This helps doctors tailor your care rather than using a one-size-fits-all approach.
United Kingdom · Scotland - completed
MWIQ - AI-powered decision support tool for diabetes clinicians
This study tests a new computer tool called MyWay IQ. It uses artificial intelligence (AI) to help GPs in Greater Manchester choose the best treatments for adults with diabetes. Researchers want to see if the tool is safe, helpful, and easy to use during normal clinic appointments.
United Kingdom · England - completed
The PRomotion Of Physical activity through structured Education with differing Levels of ongoing Support for those with pre-diabetes (PROPELS)
This study looks at whether regular support to help people stay active can stop or delay type 2 diabetes. It is for people with pre-diabetes (blood sugar that is higher than normal). Over four years, researchers will test if extra advice, phone calls, and texts help people keep active.
United Kingdom · England - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
An open label, balanced, randomized, single dose, two treatment, two period, two sequence, crossover, bioequivalence study comparing Dapagliflozin tablets 10mg, manufactured by Sun Pharmaceutical Industries Limited, India with Forxiga (Dapagliflozin) film-coated tablets 10 mg, manufactured by AstraZeneca AB Gärtunavägen, SE-151 85 Södertälje Sweden, in healthy adult, human subjects under fasting condition
This study compares two different 10mg dapagliflozin tablets in healthy adults to see if they work the same way in the body. It's a simple test to make sure generic versions of the medicine are as effective as the original.
Romania - recruiting
Introducing diabetes checks in dental settings: a study to explore whether dental settings can be used to identify new cases of prediabetes and diabetes
This study looks at whether dentists can help spot early signs of diabetes in their patients. Dentists are often seen regularly, which might make them a good place to check for diabetes early. It involves a simple questionnaire and a finger-prick test.
United Kingdom · England · Northern Ireland - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Randomised, crossover bioequivalence clinical trial of linagliptin 5 mg film-coated tablets, after a single oral dose administration to healthy volunteers under fasting conditions.
This study is testing if a new version of linagliptin tablets, a medicine for diabetes, works the same as the original. Healthy volunteers take a single dose to see how the body absorbs it. This helps make sure new medicines are just as effective.
Spain - recruiting
Benefits of Retained Insulin for Good Health
This research looks into how making your own insulin, even a little, might help people with diabetes live better. It checks how this natural insulin affects health and daily life, and aims to find the best ways to measure it at home to help future diabetes treatments.
United Kingdom - active not recruiting
Meta-Analyses of the Effect of Plant Protein Versus Animal Protein on Cardiometabolic Risk
This study looks at lots of past research to see if swapping animal protein for plant protein makes a difference to health conditions like diabetes, heart problems, and kidney issues. They want to understand if eating more plant-based protein, like from beans or nuts, can be better for our health.
Canada - active not recruiting
Preoperative Optimization of Diabetic Patients
This study looks back at records of adults with diabetes having surgery in Alberta, Canada. It aims to understand how many surgical patients have diabetes, how well their diabetes is managed before surgery (using a blood test called HbA1C), and if this management affects their recovery and hospital stay.
Canada - recruitingEARLY_PHASE1
Akkermansia Muciniphilia and Metabolic Side Effects of ADT
This study looks at whether apple cider vinegar can increase beneficial gut bacteria in men with prostate cancer starting hormone therapy. Researchers want to see if this helps reduce side effects like weight gain and diabetes, which can be linked to their treatment.
Canada - enrolling by invitation
Assessing Remote Confirmation of Type 1 Diabetes
This study looks at sending home finger-prick kits to people treated for Type 1 diabetes to check how much insulin their body makes. This helps see if a simple home test can accurately check for Type 1 diabetes, potentially helping some avoid unnecessary insulin.
United Kingdom - recruitingNA
Personalized Responses to Dietary Composition Trial 3
This study, PREDICT 3, aims to understand how different foods affect individuals. By looking at how people respond to meals in their everyday life, it helps create more personalised eating advice to improve health for conditions like diabetes and heart problems.
United States · United Kingdom - recruiting
French Prospective Multicentric Study in Real World
This study looks at how a device called Omnipod 5 helps people with Type 1 diabetes in France. It checks blood sugar control, how it affects their daily lives, and how happy they are with the system, over 12 months.
France - recruiting
Impact of Semaglutide (Ozempic/Wegovy®) on Heart and Muscle Mass
This study looks at how a medicine called semaglutide (Ozempic/Wegovy®) affects your heart and muscles over a year. Researchers use special scans and tests to understand if it helps keep your muscles healthy, especially if you have type 2 diabetes or obesity.
Canada - recruitingNA
Exploratory Evaluation of the Effect of Cholestyramine on Serum Levels of POPs in Obese Female Patients
This study looks at whether a medicine called cholestyramine can help reduce levels of certain chemicals in obese women before weight-loss surgery. These chemicals, called POPs, can build up in fat and might be released after surgery, potentially causing health concerns for mothers and babies.
France - active not recruiting
Smart Watch Insights for Prevention of Exacerbations and Enhance Rehabilitation - Movement Study
This study uses smartwatches to understand how movement affects health for people with conditions like heart disease or diabetes. Researchers hope to find ways to predict health changes and improve wellbeing programmes using the information from the watches.
United Kingdom - recruitingNA
Diabetes Interventional Assessment of Slimming or Training to Lessen Inconspicuous Cardiovascular Dysfunction
This study looks at how type 2 diabetes affects the heart in younger adults. We're testing if a special diet plan or an exercise programme can improve heart health and reverse fatty changes in the liver and heart, compared to standard care.
United Kingdom - active not recruitingNA
Pharmacist Case Finding and Intervention for Vascular Prevention Trial
This study looks at how pharmacists can help people lower their risk of heart disease. Heart disease is very common, and pharmacists often see patients. They might be able to help you understand and reduce your personal risk factors for heart problems.
Canada - recruitingNA
Efficacy of Automated Insulin Therapy Early Initiated After Diagnosis on Blood Glucose Control in Children and Adolescents With Type 1 Diabetes
This study looks at a new automated insulin system for children and teenagers recently diagnosed with Type 1 diabetes. It compares this system to standard treatments to see if it helps manage blood sugar levels better and makes living with diabetes easier for families.
France - recruiting
Impact of Smart Connected Insulin Pens on Quality of Life in Dependent Patients with Diabetes Using Continuous Glucose Measurement
This study looks at how smart insulin pens and continuous glucose monitors can help improve diabetes care for adults who need help managing their insulin. It aims to see if guiding caregivers on using these tools can lead to better health and fewer problems for patients.
France - not yet recruitingNA
Feasibility Testing of Plant-Based Meal Replacement Products Made With Manitoba Crop Ingredients for Weight Loss and Diabetes Remission
This study looks at whether plant-based meal replacements (like shakes or bars) can help people in a weight loss clinic lose weight and potentially reverse pre-diabetes or diabetes. Researchers want to see if these meal replacements are easy to use and effective when added to a standard weight loss program.
Canada - active not recruitingPHASE3
Semaglutide 2.4 mg in Patients With Poor Weight-loss
This study is looking at whether a medicine called semaglutide, given as a 3mg injection, can help people who haven't lost enough weight after weight-loss surgery. It compares semaglutide to a dummy treatment over 68 weeks to see if it helps with weight loss and overall health.
United Kingdom - active not recruiting
Myotonic Dystrophy - Vascular and Cognition
This study looks at how myotonic dystrophy type 1 affects the brain and thinking skills. Researchers want to see if problems with sugar processing, like diabetes, are linked to memory and planning difficulties in people with this condition. They will use brain scans and thinking tests to find out more.
France - recruiting
A Biological Atlas of Severe Obesity (Biological Tissue Collection)
This study aims to understand how our genes and lifestyle choices contribute to severe obesity and type 2 diabetes. Researchers will collect tiny tissue samples during planned surgery to learn more about how these complex health conditions develop in different people.
France - recruitingNA
Study of the Factors Favoring the Transition From Prediabetes to Diabetes on Reunion Island.
This study looks at why some people with pre-diabetes on Reunion Island go on to develop type 2 diabetes. Researchers want to understand the factors involved to help prevent diabetes in this community, where it is a significant health concern.
France - recruiting
Kidney Check: Diabetes, Blood Pressure & Kidney Health Checks & Care in Indigenous Communities.
This study offers free kidney health checks for Indigenous people aged 10-80 in rural areas of Canada. It aims to find kidney problems early, and those at risk of diabetes and high blood pressure, to improve care and create a lasting health system for these communities.
Canada - recruiting
Cardiometabolic Health in First Time Pregnancy
This study looks at how pregnancy complications like high blood pressure can affect a woman's heart health and risk of diabetes later on. It aims to understand these links better and find ways to prevent future problems.
United Kingdom - recruitingNA
The Man Van Project
The Man Van project offers mobile health checks at workplaces and communities for men, especially those from ethnic minority groups, to find health problems like prostate cancer early. The goal is to make healthcare easier to access and improve men's health outcomes.
United Kingdom - active not recruiting
User Evaluation of a Home-collection Kit for People With Diabetes
This study is testing a new home blood test kit for people with diabetes. It aims to make it easier for you to check your diabetes control (HbA1c) from home, so you don't always need to visit a clinic. We want to see if these home kits work well and are helpful.
United Kingdom - active not recruitingNA
Enhanced DPP-GLB to Promote Weight Loss Among Nonresponders in a Community-Based Lifestyle Intervention.
This study looks at how to help people who are finding it hard to lose weight in a community-based program. It focuses on those at risk of diabetes, especially Black adults, offering extra support and resources to see if it helps them lose weight and stay healthier.
United States - recruitingNA
Low Energy Diet and Familial Partial Lipodystrophy
This study looks at how a special low-calorie diet can help people with a rare condition called familial partial lipodystrophy and type 2 diabetes. Participants will follow the diet for 12 weeks, aiming to improve their health and understand why the diet works.
United Kingdom - active not recruiting
Unrecognised Comorbidity Detection in Hospitalised Patients
This study aims to find hidden long-term conditions like diabetes and heart problems in hospital patients. By using routine hospital information, researchers hope to build a digital tool to identify patients who might benefit from earlier diagnosis and treatment, improving their health outcomes.
United Kingdom