- recruitingTherapeutic confirmatory (Phase III)
Contribution of PET (positron emission tomography) scans for the preoperative assessment of symptomatic endometriosis lesions: TEP-ENDORUN
This study is testing a special type of scan called a PET scan to see how well it finds endometriosis before surgery. Doctors want to compare the scan's findings with what they see during an operation. It aims to improve how we detect and plan for treating endometriosis.
France - not yet recruiting
Investigation of the diagnostic accuracy of a new blood test for endometriosis, compared with the current gold standard surgery for diagnosis
This UK study is testing a new blood test to diagnose endometriosis. Researchers want to see if the blood test is as accurate as keyhole surgery. Women already booked for their first diagnostic surgery will give an extra blood sample to help find out if future patients can avoid an operation.
United Kingdom · England · Scotland - active not recruitingPHASE2
A Phase 2 Trial to Investigate Efficacy and Safety of Vipoglanstat in Women With Endometriosis
This study is testing a new medicine, Vipoglanstat, for women with endometriosis. We want to see if it helps reduce ongoing pelvic pain that isn't related to periods and if it's safe to use. Half the women will get the new medicine, and half will get a dummy pill.
Bulgaria · Czechia · Hungary - recruitingPhase II
ENDOCAN-1: A study to see if CBD (cannabinoid) can help with endometriosis-related pain
This study, called ENDOCAN-1, is looking into whether a special liquid medicine called MRX1, which contains a part of cannabis called CBD but without the 'high' effects, can help women with endometriosis pain. It aims to find new pain relief options.
United Kingdom · Scotland - recruitingNA
Whole-Body Cryotherapy as a Non-Pharmacological Treatment to Reduce Chronic Pelvic Pain and Improve Quality of Life in People With Endometriosis
This study looks at whether whole-body cryotherapy, which is brief exposure to very cold temperatures, can help people with endometriosis reduce their pain and improve their quality of life. It’s testing if this non-drug treatment safely manages symptoms.
United Kingdom - recruitingNA
Evaluating the Feasibility of elleFA App Implementation
This study is testing a new smartphone app called elleFA, made for women with endometriosis. It aims to see if the app helps women track their symptoms and communicate better with their doctors. We want to find out how easy it is to use the app and if it improves patients' experiences.
Canada - recruitingNA
Argon Plasma Treatment for Ovarian Endometrioma Compared to Standard Cystectomy
This study compares two ways to treat ovarian endometriomas (cysts from endometriosis) to see how they affect a woman's egg count. We're looking at a standard surgery versus a newer argon plasma treatment. It's for women aged 18-40 in Germany.
Germany - recruiting
Predicting the Pain Outcome of Surgery for Endometriosis
This study looks at whether surgery helps with pain in severe endometriosis. We're using brain scans to see who might benefit most. This helps us understand if surgery is the best option for pain relief for some women.
United Kingdom - active not recruitingNA
Efficacy of Internet-based Cognitive Behavioral Therapy for Endometriosis
This study is looking at a type of online talking therapy called Cognitive Behavioural Therapy (CBT) to help people manage the challenges of endometriosis. It aims to see if this online approach can reduce the difficulties caused by the condition.
Germany - recruitingNA
Pesticides and Infertility: Oxidative Stress Via Circulating Cell-free DNA and Gut/Genital Microbiome Signatures in Women With Endometriosis
This study looks into how pesticides might affect women with endometriosis, especially regarding fertility. Researchers are exploring how gut and vaginal germs, along with tiny bits of DNA, could be linked to the condition and exposure to chemicals.
France - recruiting
Multicenter Study for Diagnostic Validation of a Laboratory Test for the Diagnosis of Endometriosis
This study is testing a new, simple lab test to diagnose endometriosis from menstrual blood. It aims to find out if this non-invasive test can accurately identify endometriosis and help people get diagnosed more quickly without surgery.
Austria · Germany - recruiting
Determination of Lipocalin Type-prostaglandin (L-PGDS) in Blood, Urine, Vaginal Samples and Endometrial Ablation by Enzyme-linked Immunosorbent Assay
This study is looking into a body chemical called L-PGDS and its possible link to conditions like adenomyosis and endometriosis. Researchers want to see if changes in L-PGDS levels could help diagnose adenomyosis more easily, perhaps with blood or urine tests.
France - not yet recruitingNA
Identify a Specific Immune Profile in Patients With Chronic Pelvic Pain Resistant to First-line Treatments by Measuring Th1, Th2, Th17, and Treg Cytokines Produced After Non-specific Functional Cell Stimulation - ImmunoCPP
This study looks into the immune system of women aged 18-40 with ongoing pelvic pain, especially those with endometriosis, whose pain hasn't improved with usual treatments. It aims to see if specific immune responses are linked to their pain to help find better ways to treat it.
France - active not recruiting
Endometriosis and Health Care System Utilization in British Columbia
This study in British Columbia is looking at how women with endometriosis use healthcare services. It aims to understand the costs involved, how well different treatments work, what predicts surgical outcomes, and the impact of the COVID-19 pandemic on their care.
Canada - recruiting
Ureteric Identification Using Indocyanine Green Dye Versus Conventional Ureteric Stenting to Reduce Post-operative Pain and Surgical Morbidity During Endometriosis Surgery
This study looks at a new way to protect important tubes during surgery for deep endometriosis. Instead of using tiny tubes called stents, which can cause pain, doctors are trying a special dye. This might make recovery easier and reduce discomfort after the operation.
United Kingdom - recruiting
Evaluation of the Long-term Therapeutic Effect of High-Intensity Focused Ultrasound (HIFU) Treatment in Patients With Rectal Endometriosis
This study looks at how well a treatment called HIFU works long-term for women with endometriosis in their bowel. Researchers are checking in with women who've already had this treatment to see how they're doing by asking them to fill out a questionnaire and having a phone chat.
France - recruitingNA
The Role of Cytokines and Regulatory T Lymphocytes in Migraine Pathophysiology.
This study looks into why some people get migraines, especially those with other health conditions like autoimmune diseases. Researchers are examining how chemicals in the body, called cytokines, and special immune cells, called Treg cells, might be linked to migraine pain. They hope to better understand migraine causes.
France - recruitingNA
Treatment of Chronic Pelvic Pain Due to Endometriosis by Transcutaneous Auricular Vagus Nerve Stimulation
This study looks at a new way to help women with ongoing pelvic pain from endometriosis. It uses a gentle electrical stimulation applied to the ear, called transcutaneous auricular vagus nerve stimulation (t-VNS). The goal is to see if this treatment can reduce pain more effectively for those who haven't found enough relief from other treatments.
France - recruitingNA
Educational Program for the Multidisciplinary Support of Patients With Endometriosis
This study looks at a special education programme and phone support for women with endometriosis. It aims to see if this helps improve their daily life and could be a useful way to support more women with this condition across the country.
France - recruitingNA
Developing a Complex ex Vivo Endometrial Tissue Model to Improve Endometriosis Care
This study aims to create a better lab model of endometriosis. This model will help scientists understand the condition better and find new ways to test how different hormone treatments work for each person. This could lead to more personalised care for women with endometriosis.
France - not yet recruiting
" Development of Primary Cultures of Diaphragmatic Myoblasts for Basic Research Purposes "
This study aims to grow and study diaphragm muscle cells from women having surgery for endometriosis. This will help scientists understand specific breathing muscle diseases better and could lead to new treatments in the future for conditions like ALS.
France - recruitingPHASE2, PHASE3
Benefit of GnRH Agonist Before Frozen Embryo Transfer in Patients With Endometriosis and/or Adenomyosis
This study looks at whether a hormone injection called GnRH agonist, given before a frozen embryo transfer, can help women with endometriosis or adenomyosis get pregnant. Researchers want to see if this injection, used alongside standard treatments, improves the chances of a successful pregnancy.
France - enrolling by invitation
Combining Ultrasound and Biomarkers to Diagnose Superficial Endometriosis
This study is looking for better ways to diagnose superficial endometriosis (SE), a common type of endometriosis that causes pain. Researchers are testing a new ultrasound method called SonoPODography (SPG) and looking at chemicals in fluid to see if they can help find SE without surgery.
Canada - enrolling by invitation
Vaginal Ecosystem and Network in the United States Study
This study looks at the tiny living things inside the Vagina to understand how they affect common female health issues. By collecting a simple swab, researchers hope to improve how doctors diagnose and treat conditions like thrush and UTIs.
United States · Canada - recruitingNA
ENDOmetriosis Robotic Assisted Surgery
This study looks at robot-assisted surgery versus traditional keyhole surgery for womb removal in women with specific endometriosis and adenomyosis, aiming to find the safest method with fewer complications. It focuses on women whose digestive system is not affected.
France - not yet recruitingNA
Innate Immunity, MIcrobiota and Inovative Treatments in Endometriosis
This study looks into new ways to understand and treat endometriosis. Researchers are studying how the body's natural defences and gut bacteria might be connected to this condition, hoping to find better ways to help women who suffer from it.
France - recruiting
Evaluation of Salivary RNA in Subjects Scheduled for Surgery for a Gynecologic Pathology
This study looks for clues in your spit to help diagnose common gynaecological problems like endometriosis, ovarian cysts, and cancers. It aims to find new ways to spot these conditions by examining special genetic material (RNA) in saliva.
France - recruiting
Retinal Imaging for Systemic Inflammation in Endometriosis
This study looks at eye scans in women with and without endometriosis. We want to see if these scans can help us understand more about how endometriosis affects the whole body, especially inflammation, aiming for an easier way to check on the condition.
United Kingdom - authorisedPhase III and phase IV (Integrated)
CARESS Study: Cabergoline for the Reduction of Endometriosis Symptoms and Lesion Size
This study, called CARESS, is looking at how a medicine called cabergoline might help people with endometriosis. Researchers want to see if it can shrink endometriosis growths and reduce pelvic pain. It's in the later stages of testing to make sure it's safe and effective.
Spain - recruiting
ENDO1000 - A UK-wide Endometriosis Research Project
This UK study wants to improve how we diagnose and treat endometriosis. If you have endometriosis, you can share your experiences through an app, and some might provide samples and wear a smartwatch. This helps researchers understand the condition better for future personalised care.
United Kingdom - recruiting
Imaging of Endometriosis With Total-body PET-CT (PET-Endo)
Researchers are investigating a new way to find endometriosis using special scans called PET/CT and PET/MRI. They want to see if these scans can spot different types of endometriosis and understand how it changes over time, aiming to improve diagnosis and treatment.
United Kingdom