- completed
MOVE SMART – a feasibility study in patients with psoriasis
The MOVE SMART study looks at whether breaking up sitting time can help people with psoriasis. Sitting for long periods can harm health and increase heart risks. This 24-week home study tests if regular, two-minute movement breaks improve skin symptoms, heart health, and general well-being without needing hospital visits.
United Kingdom · England - recruitingHuman Pharmacology (Phase I)- Other
A study to compare how the body absorbs different formulations of a new medicine, and how food affects drug absorption, in healthy participants
This study is looking at how a new medicine for psoriasis is taken up by the body and if food changes this. It's for healthy volunteers to help us understand the medicine better before it's given to people with psoriasis.
Netherlands - recruitingPhase III
Trial to investigate the benefits of two drugs, adalimumab and methotrexate, in treating patients with moderate psoriasis
This UK study compares two treatments for moderate plaque psoriasis: methotrexate and adalimumab. Methotrexate is a standard treatment, while adalimumab is a newer biologic injection usually reserved for severe cases. Researchers want to see if adalimumab works better, causes fewer side effects, and provides good value for the NHS.
United Kingdom - recruitingTherapeutic exploratory (Phase II)
A phase 2B, multicenter, randomized, double-blind, placebo-controlled, dose-finding, efficacy and safety study of HRO350 in subjects with mild-to-moderate psoriasis (the ‘HeROPA’ study)
This study is testing a new treatment called HRO350 for people with mild to moderate psoriasis. Researchers want to see if it improves psoriasis symptoms and is safe to use. Some people will get HRO350, others will get a dummy treatment, to compare results over 26 weeks. It's for adults aged 18 and over.
Finland · Germany · Norway - recruitingTherapeutic exploratory (Phase II)
A Phase 2, International, Multicenter, Randomized, Double-blind, Placebo-controlled, Dose-ranging study of Efficacy and Safety of SAR441566 in Adults with Moderate to Severe Plaque Psoriasis
This study is testing a new medicine called SAR441566 for moderate to severe plaque psoriasis. Researchers want to see if it helps improve psoriasis symptoms and if it's safe. It's a key step to understand if this medicine could become a future treatment option.
Spain · Germany · Hungary - active not recruitingPHASE3
Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis
This study looks at the everyday safety and effectiveness of a new medicine, deucravacitinib, for people with psoriasis who have been in previous studies. It also checks how the body responds to common vaccines while taking this medicine.
United States · Australia · Canada - active not recruiting
A Study to Evaluate the Safety of Remsima® SC in the Treatment of RA, AS, PsA and Ps
This study looks at how safe a medicine called Remsima® SC is for people with certain long-term conditions like rheumatoid arthritis, a type of spinal arthritis, psoriatic arthritis, and psoriasis. It aims to see if there are any unwelcome side effects.
France - recruitingNA
Assessment of the Effect of a Dermatology-Oriented Spa Therapy on the Quality of Life of Patients With Psoriasis
This study looks at how a special skin spa treatment might improve the lives of people in the UK with psoriasis. It checks if their quality of life gets better after a 3-week stay at a dermatology-focused spa, over several months.
France - active not recruiting
Tilrdakizumab Almirall
This study is looking at how a medicine called tildrakizumab works in people with moderate to severe psoriasis. Researchers are studying skin samples to understand how this treatment helps improve psoriasis and how its effects last over time.
Germany - recruiting
PsoBest - The German Psoriasis Registry
PsoBest is a long-running study in Germany looking at how well different medicines work for psoriasis and psoriatic arthritis in real life. It aims to understand the long-term effects, safety, and best ways to use these treatments for patients.
Germany - not yet recruiting
Characterization of the Fungal Immunopeptidome Involved in the Immunopathological Mechanisms of Psoriasis
This study looks into how common fungi on our skin and in our gut might be linked to psoriasis. Researchers want to understand if these fungi trigger the immune system, causing the skin problems seen in people with psoriasis, hoping this will lead to new treatments.
France - recruiting
Molecular Signatures in Inflammatory Skin Disease
This study looks at people with skin conditions like eczema and psoriasis to understand how their bodies respond to new treatments. We want to find patterns in their genes and cells to help doctors choose the best medicine for each person in the future.
Germany - recruitingNA
Walk and Talk: Connecting People With Psoriasis
This study looks at creating 'Walk and Talk' groups for people with psoriasis. It aims to see if these groups help improve social connections, physical activity, and overall wellbeing, and how best to run them.
United Kingdom - active not recruitingNA
Effectiveness of a Digital Health Application for Psoriasis
This study is looking at an online program to help people in Germany with psoriasis manage their condition better. It aims to see if using this program for a year, alongside their usual care, improves their quality of life compared to just receiving their usual care.
Germany - recruitingNA
Meditation in Inflammatory Dermatosis
This study looks at how mindfulness meditation can help people with skin conditions like eczema and psoriasis. It aims to see if meditation can reduce itching, improve mood, and make skin less inflamed.
France - active not recruitingPHASE3
Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis
This study looks at how safe and effective a new medicine, ESK-001, is for people with moderate to severe plaque psoriasis over a long time. It builds on previous studies and carefully watches patients who continue treatment.
United States · Australia · Bulgaria - active not recruiting
Canadian Real World Evidence Study of Brodalumab in Plaque Psoriasis to Understand the Impact on Quality of Life and Work Productivity
This study looks at how a medicine called brodalumab affects the lives of people with psoriasis in Canada. It will check how it helps with quality of life and work over 12 months in about 500 adults already starting this treatment.
Canada - recruiting
SEquential Treatment of PSoriasis With Biologics
This study looks at how well different psoriasis treatments called biologics work when people try several in a row. It uses existing health records to understand if these treatments become less effective over time. No extra appointments are needed for this research.
United Kingdom - recruiting
HIPPOCRATES Prospective Observational Study
This study aims to find out why some people with psoriasis get psoriatic arthritis. We'll use questionnaires and some blood samples to help identify those at risk. Our goal is to one day prevent arthritis from developing.
United Kingdom - active not recruitingPHASE3
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 6 and 17 Years With Moderate to Severe Plaque Psoriasis Treated With Subcutaneous (SC) Injection of Risankizumab Who Have Completed Participation in Study M19-977
This study looks at a medicine called risankizumab for children aged 6 to 17 with moderate to severe psoriasis. It checks for side effects and how well the medicine works in those who were part of an earlier study. Risankizumab is already used for adults with psoriasis.
United States · Canada · Germany - active not recruiting
A Safety Study of Ustekinumab in the Treatment of Pediatric Participants Aged 6 Years and Older With Moderate to Severe Plaque Psoriasis
This study looks at the long-term safety of ustekinumab in children and teenagers (6-17) with moderate to severe plaque psoriasis. Researchers will monitor for serious infections, cancers, and autoimmune issues, as well as checking the drug's effects on growth and development.
Austria · Belgium · Denmark - authorisedTherapeutic use (Phase IV)
A Phase 4 Mechanistic Longitudinal Study to Evaluate the Impact of EARLY Risankizumab Treatment on TRM Cell Levels in Moderate-to-Severe Psoriasis
This study looks at how an early treatment for moderate to severe psoriasis, called Skyrizi, affects certain cells in the skin. Researchers want to see if starting treatment sooner helps reduce these cells more effectively than starting later, and how clear the skin becomes.
Spain - not yet recruiting
Evidencing Vibroacoustic Sensing for Inflammatory Skin Disease Monitoring
This study is testing a new device that uses sound waves to check skin conditions like eczema and psoriasis. It aims to see if this device can help doctors understand how severe your skin condition is and how well treatments are working, without long waits for specialist appointments. We need volunteers aged 18-75 with eczema or psoriasis starting new treatment.
United Kingdom