Latest studies
- RecruitingPHASE3
The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease
This study looks at a new drug, Rilzabrutinib, for people aged 10-65 with sickle cell disease. We'll see how well it works and if it's safe compared to a dummy pill to help reduce painful crises.
Sickle Cell DiseaseGhana - Active not recruitingPHASE3
A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS)
This study is testing a new tablet medicine called etavopivat for people aged 12 to 65 with sickle cell disease. It aims to see if the medicine can improve a patient's red blood cells and reduce painful sickle cell crises. Half the group will receive the new treatment, the other a placebo.
Sickle Cell DiseaseGhana - RecruitingPHASE2, PHASE3
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
This study is testing a new medicine, VX-147, for people aged 10-65 with a specific type of kidney disease caused by a gene problem. It will check if the medicine helps, if it's safe, and how the body handles it.
Proteinuric Kidney DiseaseGhana - RecruitingPHASE3
A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
This study is testing a new medicine, Etavopivat, for sickle cell disease and thalassaemia. It looks at how safe and effective the treatment is over a long period for people already benefiting from it in previous studies. The goal is to improve oxygen delivery in the body.
Sickle Cell DiseaseThalassemiaGhana - Recruiting
EMUs: Enhanced Monitoring Using Sensors After Surgery
This study looks at using small, wearable sensors to spot if patients are becoming unwell after surgery. It aims to see if these sensors can help nurses and doctors notice problems sooner, making recovery safer for patients.
SurgeryInpatientsGhana - Active not recruitingPHASE3
Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients
This study is looking at a new medicine called crizanlizumab to see if two different doses can help teenagers and adults with sickle cell disease. We want to find out if it's safe and if it can reduce pain crises (VOCs) compared to a dummy medicine (placebo).
Sickle Cell Disease (SCD)Ghana - Not yet recruitingNA
Study on the Medical Education Capability of the EyeTeacher Artificial Intelligence Platform
This study looks at a new AI learning tool called EyeTeacher for medical students. It helps teach about eye care using advanced technology. We want to see if EyeTeacher works better than traditional ways of learning for students who haven't studied ophthalmology before, across different countries and languages.
Medical EducationGhana - Active not recruitingPHASE3
A Study Evaluating Atezolizumab and Bevacizumab, With or Without Tiragolumab, in Participants With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) (IMbrave152)
This study is looking at new ways to treat advanced liver cancer that can't be removed by surgery. It combines existing medications with a new one to see if this mix works better and is safe. The aim is to find improved first-line treatments for this type of cancer.
Hepatocellular CarcinomaGhana - RecruitingPHASE3
Randomised Evaluation of COVID-19 Therapy
The RECOVERY trial looks at treatments for serious lung infections like pneumonia, including COVID-19. It helps doctors find the best ways to help hospitalised patients get better and reduce their risk of dying. Many treatments have been tested, and some have been found to be very helpful.
PneumoniaGhana - RecruitingPHASE3
A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
This study looks at a new medicine called etavopivat for people with sickle cell disease. It aims to see if it reduces painful crises, organ damage, and tiredness, and improves exercise. Participants will get either the medicine or a dummy pill.
Sickle Cell DiseaseGhana