A Retrospective Study to Evaluate Treat-to-Target and Disease Modification in Adult Participants With Crohn's Disease and Ulcerative Colitis in Real World Setting
This study is a look back at the medical records of adults living with Crohn's disease or ulcerative colitis, which are types of Inflammatory Bowel Disease (IBD). These conditions can cause ongoing gut inflammation. Doctors often use a 'treat-to-target' strategy to manage IBD, aiming for specific health goals to improve long-term well-being. This research wants to understand how this 'treat-to-target' approach is actually used in clinics around the world and if it's linked to better health results for patients. It's an observational study, meaning researchers will simply review existing patient data, so there are no extra appointments or treatments involved for patients taking part.
At a glance
What is this study about?
This study focuses on Inflammatory Bowel Disease (IBD), which includes Crohn's disease and ulcerative colitis. These are ongoing conditions that cause inflammation in your digestive system and can lead to various symptoms and difficulties. To help people with IBD live better lives, doctors often follow a 'treat-to-target' strategy. This means they set specific goals for treatment, like reducing inflammation to certain levels, to try and achieve the best possible long-term health for the patient.
Researchers want to see how this 'treat-to-target' approach is actually used by doctors in different places and understand if it genuinely helps improve patient outcomes over time. They will be looking at existing medical records from adults who have had Crohn's or ulcerative colitis for at least two years. By studying this information, they hope to get a clearer picture of how effective this treatment strategy is in the real world.
This is called an 'observational' study because the researchers are not giving new treatments or asking patients to do anything differently. Instead, they are simply reviewing medical information that has already been collected as part of routine patient care. This helps them understand patterns and connections in how the disease is managed and how patients respond, without adding any burden to the patients themselves.
Key takeaways
- This study looks at existing medical records of adults with Crohn's or ulcerative colitis.
- It aims to understand how a 'treat-to-target' approach helps manage these conditions.
- No new treatments, visits, or tests are involved for participants.
- The study reviews medical information from the past 24 months.
- It could help improve future care for people with IBD.
Who may be eligible?
To be part of this study, you need to be an adult, aged 18 years or older. You must have been diagnosed with either Crohn's disease or ulcerative colitis for at least two years.
It's important that there are at least two years of your medical records available for the researchers to look at. You also need to be able to understand and agree to take part in the study.
You would not be able to join if you have received any experimental treatments (drugs, devices, or procedures that are still being tested) in the last two years. Also, if you have had a specific surgery called a proctocolectomy (where the rectum and colon are removed), you wouldn't be eligible. People under legal protection also cannot participate.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you 18 years old or older?
- Have you been diagnosed with Crohn's disease or ulcerative colitis for at least 2 years?
- Have you not received any experimental treatments in the last 2 years?
- Have you not had a proctocolectomy surgery?
- Are you able to agree to take part in the study?
What does participation involve?
Taking part in this study is very straightforward because it involves looking back at your existing medical records. You won't need to visit the clinic specifically for the study. There will be no extra appointments, no new tests, and no changes to your current medication or treatment plan. The researchers will simply review information already in your medical file from the past 24 months. Your doctor will continue to manage your condition as usual. This means there's no additional time commitment or burden on you.
Potential risks and benefits
Locations (4)
- Chongqing General Hospital /ID# 282777Verified postcodeChongqing, China· Recruiting
- Centre Hospitalier Universitaire de Nîmes - Hôpital Universitaire Carémeau /ID# 282775Verified postcodeNîmes, France· Not yet recruiting
- Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois /ID# 280265Verified postcodeVandœuvre-lès-Nancy, France· Not yet recruiting
- CHU Amiens-Picardie Site Sud /ID# 280263Verified postcodeAmiens, France· Not yet recruiting
Common questions
What is 'treat-to-target'?
It's a treatment approach where doctors set specific goals for your health management, like reducing inflammation, and adjust your treatment to reach those goals.
Will I have to take new medicine?
No, this study only looks at your existing medical records. It won't involve any new medicines or changes to your current treatment.
Do I need extra doctor's appointments?
No, you don't. This study reviews information already in your medical notes, so there are no extra appointments required.
Is my personal information safe?
The study uses information from your records, and personal details are handled carefully to protect your privacy, as is standard practice for medical research.
Can I leave the study if I change my mind?
Yes, you can. You are free to withdraw your consent at any time without it affecting your medical care.
How to find out more
Colla Cunneen
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
Discussion
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