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Prediction of Heart Failure and Cognitive Decline in Type 2 Diabetes

If you have Type 2 diabetes, this study aims to understand why some people develop heart failure (when your heart doesn't pump blood as well as it should) or cognitive decline (issues with memory and thinking). We know Type 2 diabetes can increase the risk of both these conditions, but often, early heart problems show no symptoms. Similarly, diabetes can affect your brain. By identifying people at higher risk, researchers hope to develop personalised ways to prevent these conditions. This is important because currently, there aren't many ways to prevent heart failure at its very early stages. The study is for adults with Type 2 diabetes who do not currently have advanced heart failure or dementia.

At a glance

Status
Recruiting
Sponsor
University Hospital, Lille
Enrolment target
600
Start
22 Jun 2021
Estimated completion
01 Jun 2026

What is this study about?

This research study is looking into two important health concerns that can affect people with Type 2 diabetes: heart failure and something called cognitive decline. Heart failure means your heart isn't pumping blood around your body as efficiently as it should. Cognitive decline refers to problems with memory, thinking clearly, or making decisions. We know that Type 2 diabetes can increase the risk of both these conditions.

One of the main goals of this study is to find out why some people with Type 2 diabetes develop heart failure. Often, the early signs of heart failure can be very subtle or even non-existent, meaning people don't know they have it until it's more advanced. At the moment, there aren't many ways to prevent heart failure specifically for people at these early stages. By identifying who is most at risk, the researchers hope to develop new, personalised ways to stop heart failure from progressing.

Similarly, the study wants to understand the link between Type 2 diabetes and cognitive decline. Diabetes can affect your blood vessels and how your body uses energy, both of which can impact your brain health. Researchers want to find out which people with Type 2 diabetes might be more likely to experience problems with their memory and thinking. Once they understand this better, they can work on creating specific ways to help prevent these issues too. Ultimately, the aim is to help people with Type 2 diabetes stay as healthy as possible.

Key takeaways

  • The study helps understand how Type 2 diabetes links to heart problems and memory issues.
  • It aims to identify people at risk early, before conditions become serious.
  • The goal is to develop personalised ways to prevent these health problems.
  • No new medication is given; it's an observational study.
  • Your participation could help improve care for people with Type 2 diabetes.

Who may be eligible?

This study is looking for adults aged 18 or older who have Type 2 diabetes. You must be able to understand the study information and agree to take part. It's important that you don't already have advanced heart failure (meaning your heart condition isn't too severe) and you shouldn't have dementia, which is a condition affecting memory and thinking.

To join, you need to be part of a social security scheme, like the NHS in the UK, which confirms you have access to healthcare. You'll also need to read and sign a consent form, which explains everything about the study and confirms you agree to participate.

You cannot take part if you have dementia or if your heart problems are already at a more severe stage. The researchers want to study people before these conditions become advanced.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you an adult (18 years or older)?
  2. Do you have Type 2 diabetes?
  3. Do you currently NOT have advanced heart failure?
  4. Do you currently NOT have dementia?
  5. Are you able to understand study information and willing to sign a consent form?
Answer every question to see your result.

What does participation involve?

The details of what taking part in this study involves aren't fully described here, but generally, studies like this might ask you to attend some appointments with the research team. At these appointments, you might have some health checks, answer questionnaires about your health and lifestyle, and potentially have some tests like blood tests or scans. The study aims to look at how your health changes over time, so you might be asked to come for follow-up visits. You won't be given any new medication as part of this study, as it's about understanding risk rather than testing a specific treatment. The total duration of your involvement isn't specified, but it would typically involve a series of visits over a period.

Potential risks and benefits

Taking part in this study could offer the benefit of a deeper understanding of your own health, and you'd be contributing to valuable research that could help many others with Type 2 diabetes in the future. As with any study, there might be some minor risks, such as discomfort from blood tests or the time commitment for appointments. You are free to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (1)

  • Hopital Roger Salengro, CHU Lille
    Verified postcode
    Lille, France· Recruiting

Common questions

What is Type 2 diabetes?

Type 2 diabetes is a common condition where the body doesn't produce enough insulin, or the insulin it produces doesn't work properly, leading to high blood sugar levels.

What is heart failure?

Heart failure means your heart isn't pumping blood around your body as efficiently as it should. It can make you feel tired or breathless.

What is cognitive decline?

Cognitive decline refers to problems with your memory, thinking, or making decisions that are more than what's expected with normal ageing.

Will I receive new medicine in this study?

No, this study is about understanding risk factors, not testing new medications. Your current diabetes treatment would not change.

How long will the study last for me?

The information provided does not specify the exact duration, but you can ask the research team for this detail.

How to find out more

Charlotte Cordonnier, MD,PhD

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Prediction of Heart Failure and Cognitive Decline in Type 2 …" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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