Active not recruitingOBSERVATIONAL

Deciphering Rheumatoid Arthritis-associated Interstitial Lung Disease Pathogenesis 2

This study, called 'Deciphering Rheumatoid Arthritis-associated Interstitial Lung Disease Pathogenesis 2', aims to understand why some people with rheumatoid arthritis (RA) also develop a lung condition called interstitial lung disease (ILD). Researchers want to find out what factors might increase the risk of getting ILD if you have RA, and how the condition might develop over time. By looking at information from RA patients, with and without ILD, the study hopes to shed light on the different ways ILD can show up in people with RA and what happens as the disease progresses. This understanding could lead to better ways to identify, treat, and manage ILD in RA patients.

At a glance

Status

Active not recruiting

Sponsor

Assistance Publique - Hôpitaux de Paris

Enrolment target

509

Start

03 Feb 2020

Estimated completion

01 Oct 2027

Rheumatoid Arthritis Interstitial Lung Disease

What is this study about?

This study is called 'Deciphering Rheumatoid Arthritis-associated Interstitial Lung Disease Pathogenesis 2'. Its main goal is to understand more about a lung condition called Interstitial Lung Disease (ILD) in people who also have rheumatoid arthritis (RA). Imagine your lungs have tiny air sacs that help you breathe; ILD is a condition where the tissue around these air sacs becomes scarred and stiff, making it harder to get enough oxygen. Not everyone with RA gets ILD, and when they do, it can affect them in different ways.

The researchers want to find out what puts people with RA at higher risk of developing ILD and how the condition changes over time. They will carefully look at the medical information of people with RA, some of whom have ILD and some who don't. By doing this, they hope to get a clearer picture of how ILD shows up in RA patients, discover any genetic or molecular differences, and learn more about how the disease might progress.

This is not a study where you would be given new medicines or treatments; instead, it's about collecting information. The insights gained from this research could be really important. They could help doctors better understand, identify, and manage ILD in patients with RA in the future, potentially leading to earlier diagnosis and more effective ways to help people living with both conditions.

Key takeaways

This study helps us understand why people with rheumatoid arthritis (RA) sometimes develop a lung condition called interstitial lung disease (ILD).
It aims to identify factors that might predict who gets ILD and how it changes over time in RA patients.
Participation involves allowing researchers to review your existing medical records; no new tests or treatments are involved.
By taking part, you'll be contributing to knowledge that could improve future care for people with RA and ILD.
You must be at least 18 years old and have a confirmed diagnosis of RA to be considered.
Your decision to participate is voluntary, and you can withdraw at any time.

Who may be eligible?

To take part in this study, you need to be at least 18 years old. If you have both rheumatoid arthritis (RA) and interstitial lung disease (ILD), you could be considered for the 'cases' group. This means an established RA diagnosis, confirmed by a senior rheumatologist, and an ILD diagnosis based on special lung scans and breathing tests, confirmed by a senior lung doctor.

If you have rheumatoid arthritis (RA) but do not have interstitial lung disease, you could be considered for the 'controls' group. Again, you would need to be at least 18 years old and have an RA diagnosis confirmed by a senior rheumatologist.

For everyone, the most important thing is that you must be willing to provide your informed consent. This means you understand what the study involves and agree to take part by signing a consent form.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Do you have a diagnosis of rheumatoid arthritis (RA) that a doctor has confirmed?
If you also have a lung condition, has interstitial lung disease (ILD) been confirmed by a lung specialist through scans and breathing tests?
Are you willing to sign a consent form, showing you understand and agree to take part?

Answer every question to see your result.

What does participation involve?

This study is about collecting information, not trying out new medicines. If you take part, researchers will gather details from your existing medical records related to your rheumatoid arthritis and, for some, your lung condition. You won't be asked to visit the clinic specifically for this study, take any new medications, or undergo extra tests or procedures beyond what you'd usually have for your medical care. The study aims to understand your overall health journey related to these conditions. The duration of your participation would involve the researchers reviewing your existing medical information, so it doesn't require any ongoing commitment from your side once you've given your consent.

Potential risks and benefits

The main benefit of taking part in this study is that you would be contributing to a better understanding of how interstitial lung disease affects people with rheumatoid arthritis. This knowledge could help future patients. Because this study only involves looking at existing medical records and doesn't require any new tests or treatments, there are very few direct risks to you. Your personal information will be kept private and handled with care. Remember, deciding whether or not to take part is completely up to you, and you are free to change your mind and withdraw at any time without it affecting your usual medical care.

Locations (1)

Bichat Hospital
Verified postcode
Paris, France

Common questions

What is rheumatoid arthritis (RA)?

RA is a long-term condition that causes pain, swelling, and stiffness in the joints. It's an 'autoimmune' disease, meaning your body's immune system mistakenly attacks healthy tissue.

What is interstitial lung disease (ILD)?

ILD is a group of lung conditions where the tissue around the air sacs in your lungs becomes scarred and stiff. This makes it harder for your lungs to work properly.

Will I have to take new medicine if I join?

No, this study does not involve taking any new medicines or trying new treatments. It's about looking at existing medical information.

Do I need extra hospital visits for this study?

No, you will not need to make any extra hospital visits specifically for this study. Researchers will use details from your regular medical check-ups.

What if I change my mind about taking part?

You are free to change your mind and withdraw from the study at any time. This decision will not affect your medical care in any way.