Gastrointestinal Neoplasms research hub
4 indexed studies · 3 currently recruiting
- recruitingPHASE1
First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors
This study is testing a new drug, IDRX-42, for people with advanced gastrointestinal stromal tumors (GIST). It's the first time this drug is being used in humans. We want to see if it's safe, how the body handles it, and if it helps shrink tumors.
United States · Belgium · China - recruitingPHASE3
A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy
This study is testing a new drug, IDRX-42, for a type of cancer called GIST. It's for adults whose GIST has spread or can't be removed with surgery, and who have already tried another drug called imatinib. Researchers want to see if IDRX-42 works better and is safer than sunitinib.
United States · Australia · Belgium - recruiting
Evaluation of Neoplasia With Artificial Intelligence in Gastrointestinal Endoscopy
Doctors are testing new computer programs, called AI, to help find early signs of cancer in the stomach and bowel during endoscopy procedures. This study uses existing endoscopy images and videos to see how well AI can spot these changes.
United Kingdom - active not recruitingPHASE3
Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer
This study looks at a new drug, durvalumab, and standard chemotherapy (FLOT) for stomach or food pipe cancer that can be removed by surgery. It aims to see if this combination, given before and after the operation, is safe and effective.
United States · Argentina · Belgium