- authorisedTherapeutic exploratory (Phase II)
An Exploratory Phase II, Randomized, Open-Label, Proof-of-Concept Trial Evaluating Add-on Polyunsaturated Fatty Acid Ethyl Esters on Pain and Minimal Disease Activity in Psoriatic Arthritis Patients Starting TNF-alpha Inhibitors
This clinical study tests whether adding healthy fats (omega-3 fatty acid supplements) to standard biologic treatments helps ease joint pain in adults with psoriatic arthritis. Over six months, researchers will track pain levels, joint swelling, and overall well-being to see if this supplement offers extra relief.
Italy - recruitingTherapeutic confirmatory (Phase III)
A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, RISANKIZUMABCONTROLLED, PARALLEL-GROUP STUDY TO EVALUATE THE EFFICACY AND SAFETY OF BIMEKIZUMAB IN ADULT STUDY PARTICIPANTS WITH ACTIVE PSORIATIC ARTHRITIS
This study tests whether a medicine called bimekizumab helps adults with active psoriatic arthritis. Researchers want to see if it reduces joint swelling, eases pain, and clears skin plaques better than an existing treatment called Skyrizi or a dummy jab, while checking for any side effects.
Germany · Poland · Bulgaria - recruitingTherapeutic use (Phase IV)
A stratification trial to determine key immunological factors predicting Tofacitinib efficacy in Psoriatic Arthritis (PsA); TOFA-PREDICT
This study, called TOFA-PREDICT, looks at how a medicine called Tofacitinib works for people with Psoriatic Arthritis. Researchers want to understand why it helps some people more than others by looking at their body's chemistry before and during treatment.
Netherlands - recruitingTherapeutic confirmatory (Phase III)
A Phase III, Randomized, Double-Blind, Placebo-Controlled Study to Demonstrate the Efficacy and Safety of Tildrakizumab in Anti-TNF Experienced Subjects with Active Psoriatic Arthritis I (INSPIRE 1)
This study looks at a new medicine called tildrakizumab (also known as Ilumetri) for people with psoriatic arthritis who haven't responded well to other treatments. It aims to see if tildrakizumab can help reduce joint pain and swelling better than a dummy medicine.
Czechia · Germany · Estonia - recruitingTherapeutic confirmatory (Phase III)
A MULTICENTER, OPEN-LABEL EXTENSION STUDY TO ASSESS THE LONG-TERM SAFETY, TOLERABILITY, AND EFFICACY OF BIMEKIZUMAB IN THE TREATMENT OF SUBJECTS WITH ACTIVE PSORIATIC ARTHRITIS
This study is looking at the long-term safety and effectiveness of a medicine called bimekizumab for people with psoriatic arthritis. It checks how well the medicine works over time and if it causes any side effects, building on previous studies.
Italy · Germany · Czechia - recruitingTherapeutic confirmatory (Phase III)
A Phase III, Randomized, Double-Blind, Placebo-Controlled Study to Demonstrate the Efficacy and Safety of Tildrakizumab in Anti-TNF Naive Subjects with Active Psoriatic Arthritis II (INSPIRE 2)
This study is testing a new medicine, Ilumetri, for adults with active psoriatic arthritis who haven’t used similar medicines before. Researchers want to see if it helps reduce symptoms like joint pain and swelling, and if it’s safe to use. Half the people will get the medicine, and half will get a dummy injection.
Spain · Germany · Czechia - active not recruitingPHASE3
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs
This study is looking at a new medicine called deucravacitinib for people with active psoriatic arthritis who haven't tried certain other strong medicines for their condition before. It aims to see how well it works and if it's safe.
United States · Argentina · Australia - recruitingPhase II and Phase III (Integrated)
22104: A Randomized, Double-blind, Placebo-controlled, Multicenter Phase 2b/3 Study to Evaluate the Efficacy and Safety of Izokibep in Subjects with Active Psoriatic Arthritis
This study is testing a new medicine, Izokibep, for people with active psoriatic arthritis. We want to see if it helps reduce symptoms and if it's safe compared to a dummy medicine (placebo). It's a big study involving many people.
Hungary · Czechia · Poland - recruitingTherapeutic use (Phase IV)
U3P study - Upadacitinib in Psoriatic Arthritis Pain Processing
The U3P study is looking at how a medicine called RINVOQ (upadacitinib) helps people with psoriatic arthritis pain. Researchers will check brain scans to see how the pain changes over time, aiming to understand how this treatment works in the body.
Germany - recruitingTherapeutic use (Phase IV)
Investigating the role of JAK inhibition in achieving and maintaining disease remission in psoriatic arthritis (PsA).
This study looks at how well a medicine called XELJANZ works for psoriatic arthritis. It checks if the medicine can help people get into remission and stay there. Researchers will also see how it affects symptoms like joint and skin problems over time.
Belgium - active not recruitingPHASE3
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines
This study looks at a new drug, zasocitinib, for adults with psoriatic arthritis. It aims to see how well it works compared to a dummy drug. We're interested in people who have or haven't tried certain other treatments before.
United States · Argentina · Australia - recruiting
Sex and Gender-based Analysis of the Effectiveness of Advanced Therapies in Psoriatic Arthritis
This study looks at how psoriasis arthritis treatments work differently in men and women. Researchers hope to understand why this happens by studying biology and lifestyle factors in patients starting new medicines for their psoriatic arthritis.
Canada - recruiting
An Ex-US Study to Assess Treatment Persistence With Risankizumab in Adult Participants With Psoriatic Arthritis
This study looks at how well a medicine called risankizumab works long-term for people with psoriatic arthritis, compared to other treatments. It will help doctors understand how people use and benefit from this medicine in real life.
Argentina · Austria · Belgium - recruitingPHASE1
A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults
This study is looking at how a medicine called bimekizumab works in the body when given in different ways. It's for adults with psoriatic arthritis or a type of back pain called axial spondyloarthritis. We want to see if different ways of giving the medicine are equally safe and move through the body similarly.
United States · Bulgaria · Czechia - authorisedTherapeutic confirmatory (Phase III)
A Phase 3, Multicenter, Long-Term Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of Zasocitinib (TAK-279) in Subjects With Active Psoriatic Arthritis Who are Either Biologic DMARD-Naïve or Biologic DMARD-Experienced, Including Those With Inadequate Response to Biologic DMARDs
This study is looking into a new medicine, Zasocitinib, for people with psoriatic arthritis. It's checking its long-term safety and how well it helps their symptoms. Participants will either get Zasocitinib or a dummy medicine.
Germany · Belgium · Spain - active not recruiting
A Study to Evaluate the Safety of Remsima® SC in the Treatment of RA, AS, PsA and Ps
This study looks at how safe a medicine called Remsima® SC is for people with certain long-term conditions like rheumatoid arthritis, a type of spinal arthritis, psoriatic arthritis, and psoriasis. It aims to see if there are any unwelcome side effects.
France - recruiting
PsoBest - The German Psoriasis Registry
PsoBest is a long-running study in Germany looking at how well different medicines work for psoriasis and psoriatic arthritis in real life. It aims to understand the long-term effects, safety, and best ways to use these treatments for patients.
Germany - active not recruitingPHASE3
A Study to Evaluate the Effect of Bimekizumab on Gene Expression Biomarkers in Study Participants With Moderate to Severe Plaque Psoriasis
This study looks at how a new medicine, bimekizumab, affects skin cells in people with moderate to severe psoriasis. We're trying to understand how the medicine works at a very detailed level in both psoriasis and psoriatic arthritis.
United States · Germany · Poland - recruitingNA
Deployment o the Multidisciplinary Prospective Cohort Imminent
This study aims to better understand long-term inflammatory diseases like lupus and severe asthma. Researchers will collect information and samples to find new ways to treat these conditions, reduce side effects, and improve daily life for patients. It's about finding better treatments for the future.
France - recruitingPHASE4
A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis
This study is looking at how a medicine called Upadacitinib (Rinvoq) affects psoriatic arthritis, especially when it involves the spine. Researchers want to see if it helps reduce symptoms and improve life for people with this condition. It's a randomised trial comparing the medicine to a dummy pill.
United States · Canada - recruiting
Biobank for Inflammatory Chronic Diseases and Osteoporosis
This study aims to create a collection of blood samples from people with certain types of arthritis (rheumatoid, psoriatic, spondyloarthritis) or osteoporosis. Researchers hope to find markers in the blood that can help doctors choose the best treatments for these conditions.
France - active not recruitingPHASE3
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Study Participants With Active Psoriatic Arthritis
This study is testing a new medicine called bimekizumab for adults with active psoriatic arthritis. It compares bimekizumab to another medicine, risankizumab, and a dummy treatment (placebo), to see how well it works and if it's safe over 16 weeks.
United States · Australia · Bulgaria - active not recruitingNA
Post Market Clinical Follow-up (PMCF) Study of the A.L.P.S. Proximal Humerus Plating System
This study looks at a new surgical plate, the A.L.P.S. Proximal Humerus Plating System, used for broken upper arm bones. It aims to confirm the plate is safe and works well after it's been made available for use.
United States · Australia · Canada - active not recruitingPHASE3
Long Term Evaluation of Safety and Efficacy of Tildrakizumab in Patients With Psoriatic Arthritis
This study looks at a medicine called tildrakizumab for psoriatic arthritis. It's for people who were already in earlier studies of this medicine. The aim is to see how safe and effective it is over a longer time, helping us understand its long-term benefits.
United States · Australia · Canada - active not recruiting
An Observational Study to Assess Change in Disease Activity and Treatment Patterns of Upadacitinib When Given Alone or Co-Administered With Methotrexate in Adult Participants With Active Psoriatic Arthritis
This study looks at how a medicine called upadacitinib (RINVOQ) works for people with active psoriatic arthritis in their everyday lives. It observes how doctors prescribe it and how patients use it, either alone or with another medicine called methotrexate. No extra hospital visits are needed.
France · Germany · Greece - recruiting
HIPPOCRATES Prospective Observational Study
This study aims to find out why some people with psoriasis get psoriatic arthritis. We'll use questionnaires and some blood samples to help identify those at risk. Our goal is to one day prevent arthritis from developing.
United Kingdom - not yet recruitingNA
Rewiring the Brain-Immune Axis for Chronic Pain Using Transcranial Magnetic Stimulation in Psoriatic Arthritis
This study looks at a new way to reduce long-lasting pain in people with psoriatic arthritis. It explores using a special type of brain stimulation called rTMS to 'rewire' parts of the brain that link pain and the body's immune system, aiming for lasting pain relief.
United Kingdom - active not recruitingPHASE3
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment
This study is testing a new medication called deucravacitinib for active psoriatic arthritis. It compares the new drug to a dummy pill to see if it helps people feel better and if it's safe. It's for people new to certain treatments or who have tried one specific type before.
United States · Argentina · Australia - authorisedTherapeutic use (Phase IV)
IDENTIFICATION OF SYNOVIAL BIOMARKERS OF RESPONSE TO IXEKIZUMAB IN REFRACTORY PSORIATIC ARTHRITIS: THE PRECISE STUDY.
This study looks at how a medicine called Taltz helps people with psoriatic arthritis that hasn't responded well to other treatments. Researchers are checking if they can identify certain body signals (biomarkers) to predict who will benefit most from Taltz.
Italy - recruiting
Evaluating the Role of IL-17 as an Orchestrator of Peripheral-central Cross Talk in Depressive Symptoms
This study investigates how inflammation, particularly involving a protein called IL-17, might link certain skin and joint conditions like psoriasis and psoriatic arthritis with depression. Researchers will use special brain scans and different anti-inflammatory medicines to understand and potentially improve depression symptoms.
United Kingdom - active not recruitingPHASE3
A Study Comparing Risankizumab to Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Have a History of Inadequate Response to or Intolerance to at Least One Disease Modifying Anti-Rheumatic Drug (DMARD) Therapy
This study compares a new medicine, risankizumab, with a dummy treatment (placebo) for people with active psoriatic arthritis. It checks how safe and effective risankizumab is, especially for those who haven't responded well to other treatments.
United States · Argentina · Australia