Latest studies
- RecruitingPhase III
A randomised trial of treatments to prevent death in patients hospitalised with pneumonia
The RECOVERY trial is testing treatments for people in hospital with severe chest infections, including flu and pneumonia. Researchers want to find out which medicines help patients recover faster and save lives. Participants receive standard NHS care, and a computer randomly selects whether they also get an additional study medication.
Severe Acute Respiratory Syndrome, COVID-19 (SARS coronavirus 2 [SARS-CoV-2] infection), Influenza A, Influenza B, Viral pneumonia syndrome, Community-acquired pneumonia, Bacterial pneumonia syndromeNepal - Completed
DIAMONDS-SEARCH study: Designing new tests that can diagnose the causes of fever, including COVID-19
When you have a high fever, working out the cause can take days. The DIAMONDS study studies patterns in human genes to create a rapid blood test. Researchers hope to diagnose viral infections like COVID-19, bacterial illnesses, and inflammatory conditions in under two hours, helping future patients get the right treatment faster.
Patients with suspected infection or suspected inflammatory conditions including patients with suspected COVID-19 (SARS-CoV-2 infection)Nepal - Recruiting
Exploring the hidden burden of living with Glanzmann thrombasthenia
This study wants to hear from people living with Glanzmann thrombasthenia (GT) and their caregivers. We want to understand the daily challenges and feelings of those affected. Your stories can help improve support and understanding for everyone with GT.
Glanzmann thrombastheniaNepal - Recruiting
Prospective Study on Antimicrobial RESIstance in Chronic Pulmonary DiseasE
This study looks at antibiotic resistance in people with long-term lung conditions across the world. We want to understand how common it is, where it's happening most, and why some people are more likely to get it. This helps doctors treat lung infections better.
Chronic Lung DiseasesNepal - RecruitingNA
HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial
This study looks at treating hip fractures quickly in older patients who also have heart problems. It compares fast surgery to usual care to see if it reduces deaths within 90 days, and also checks other important health outcomes.
Hip FracturesMyocardial InjuryNepal - Active not recruitingPHASE4
EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF)
This study looks at whether a blood-thinning medicine called edoxaban can reduce the risk of stroke in people with an irregular heartbeat (atrial fibrillation) who have previously had bleeding in the brain. It compares edoxaban to not taking blood thinners.
Intracranial HemorrhagesAtrial FibrillationNepal - RecruitingPHASE4
Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial Fibrillation Occurring Transiently With Stress
This study looks at whether blood-thinning medicines (anticoagulants) can prevent strokes and other heart-related problems in people who have had temporary episodes of an irregular heartbeat called atrial fibrillation (AF) during stressful times like surgery or serious illness.
StrokeAtrial FibrillationNepal - RecruitingPHASE3
Randomised Evaluation of COVID-19 Therapy
The RECOVERY trial looks at treatments for serious lung infections like pneumonia, including COVID-19. It helps doctors find the best ways to help hospitalised patients get better and reduce their risk of dying. Many treatments have been tested, and some have been found to be very helpful.
PneumoniaNepal - RecruitingPHASE3
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
This study, called REMAP-CAP, looks at different treatments for serious lung infections like pneumonia, flu, and COVID-19 in adults needing intensive care. It aims to find out which treatments work best to help patients recover.
Community-acquired Pneumonia, Influenza, COVID-19Nepal - RecruitingPHASE3
Low INR to Minimize Bleeding With Mechanical Valves Trial
This study is looking at whether taking a lower dose of a blood thinner called warfarin is safer for people with a mechanical heart valve in their main artery. We want to see if this lower dose can prevent serious bleeding without increasing the risk of blood clots or stroke.
Bleeding Post-mechanical Valve ReplacementThromboembolism Post-mechanical Valve ReplacementNepal - RecruitingNA
Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery
This study looks at different ways of giving blood transfusions to younger patients (under 66) having heart surgery. It compares two common approaches to see which one is safer and more effective. The goal is to improve care for people undergoing these operations.
DisorderHeartPostoperativeCardiac SurgeryNepal