Clinical trials in Panama

Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients

This study is looking at a new medicine called crizanlizumab to see if two different doses can help teenagers and adults with sickle cell disease. We want to find out if it's safe and if it can reduce pain crises (VOCs) compared to a dummy medicine (placebo).

A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD)

This study is testing a new drug, Ris-Rez, for people with advanced cancers. Researchers want to see if it's safe, how it works, and if it can help stop cancer growth, both alone and with other medicines.

A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

A Study of Mocertatug Rezetecan in Combination With Anti-cancer Therapies for Advanced Solid Tumors

This study looks at a new drug, Mo-Rez, combined with other cancer treatments for advanced solid tumours – cancers that have spread. We want to see how safe and effective this combination is for people whose current treatments aren't working or who can't tolerate them.

A Study to Investigate the Safety and Efficacy of mRNA-1403 in Participants ≥18 Years of Age for the Prevention of Acute Gastroenteritis

This study is testing a new vaccine (mRNA-1403) to see if it can prevent severe stomach flu, especially the kind caused by norovirus. It will also check how safe the vaccine is and if it causes side effects in adults aged 18 and over.

Product Surveillance Registry

This study keeps track of how well Medtronic medical devices, like those for heart problems or other conditions, work in real life. It aims to make sure these devices are safe and effective for patients.

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

This study looks at a new treatment called dostarlimab for certain types of colon cancer that haven't spread. It compares dostarlimab with standard treatments to see if it works better before and after surgery to help patients.

Study to Compare the Efficacy and Safety of Olaparib When Given in Combination With Carboplatin and Paclitaxel, Compared With Carboplatin and Paclitaxel in Patients With Advanced Ovarian Cancer

This study is looking at a new way to treat advanced ovarian cancer. It combines a drug called olaparib with standard chemotherapy (carboplatin and paclitaxel) to see if it works better and is safe compared to chemotherapy alone.

A Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansine Alone or in Combination With Other Anti-Cancer Therapy in One of the Parent Studies

This study is for people with cancer that has spread, who are already benefiting from a specific medicine called trastuzumab emtansine (T-DM1) or other similar treatments in an earlier study. It allows them to keep receiving these important treatments for longer to see if they continue to help.

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

This study is testing a new medicine called Afimkibart for people with moderately to severely active Crohn's disease. It's a Phase 3 study, which means it's a big step before the medicine might become widely available, looking at how well it works and if it's safe.

Phase 2b Study of GSK4532990 in Adults With NASH

This study is testing a new medicine, GSK4532990, for people with a serious liver condition called Non-Alcoholic Steatohepatitis (NASH). We want to see if this medicine can improve liver damage and inflammation compared to a dummy medicine.

MINIject Implantation Combined With Cataract Surgery in Patients With POAG and Cataract

This study looks at combining a new small eye implant, called MINIject, with cataract surgery for people with both glaucoma and cataracts. It checks how safe and effective the implant is at lowering eye pressure when medicines haven't worked well enough.

A Study of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus in Pregnant Women and in Infants Born to Vaccinated Mothers

This study is looking at a new vaccine (mRNA-1345) for Respiratory Syncytial Virus (RSV) in pregnant women. It checks if the vaccine is safe and works well for mums-to-be, and also for their babies after they are born.

A Safety, Tolerability, and Immunogenicity Study of mRNA-1345 and mRNA-1365 in Participants Aged 5 Months to <24 Months

This study is testing new mRNA vaccines against common winter viruses, RSV and hMPV, in babies and toddlers aged 5 to 24 months. Researchers want to see if the vaccines are safe and good at triggering the body's immune response.