Latest studies
- Recruiting
Product Surveillance Registry
This study keeps track of how well Medtronic medical devices, like those for heart problems or other conditions, work in real life. It aims to make sure these devices are safe and effective for patients.
Cardiac Rhythm DisordersUrological DisordersNeurological DisordersCardiovascular DisordersPanama - RecruitingPHASE3
Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
This study looks at a new treatment called dostarlimab for certain types of colon cancer that haven't spread. It compares dostarlimab with standard treatments to see if it works better before and after surgery to help patients.
Colonic NeoplasmsNeoplasms, ColonPanama - RecruitingPHASE1, PHASE2
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed
This study is testing a new medicine, GSK5764227, for advanced bowel or pancreatic cancer that can't be removed by surgery. It will check how safe and effective it is, and how the body handles it in people who have already had other treatments.
Gastrointestinal NeoplasmsPanama - Recruiting
MINIject Global Long-Term Follow-up Study
This study is checking on the long-term safety and effectiveness of a tiny device called MINIject, used for glaucoma. It follows people who've already had the implant for two years, continuing to track their progress up to five years.
Open Angle GlaucomaOcular HypertensionPanama - RecruitingPHASE3
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
This study is testing a new medicine called Afimkibart for people with moderately to severely active Crohn's disease. It's a Phase 3 study, which means it's a big step before the medicine might become widely available, looking at how well it works and if it's safe.
Moderately to Severely Active Crohns DiseasePanama - Active not recruitingPHASE2, PHASE3
A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)
This study looks at new drug combinations for advanced non-small cell lung cancer. It aims to find out how safe and effective these treatments are for people whose cancer has specific genetic changes, using blood tests to identify these changes.
Non-Small Cell Lung CancerPanama - Enrolling by invitationNA
MINIject Implantation Combined With Cataract Surgery in Patients With POAG and Cataract
This study looks at combining a new small eye implant, called MINIject, with cataract surgery for people with both glaucoma and cataracts. It checks how safe and effective the implant is at lowering eye pressure when medicines haven't worked well enough.
Primary Open-angle GlaucomaCataractPanama - Active not recruitingPHASE2
Study to Compare the Efficacy and Safety of Olaparib When Given in Combination With Carboplatin and Paclitaxel, Compared With Carboplatin and Paclitaxel in Patients With Advanced Ovarian Cancer
This study is looking at a new way to treat advanced ovarian cancer. It combines a drug called olaparib with standard chemotherapy (carboplatin and paclitaxel) to see if it works better and is safe compared to chemotherapy alone.
Ovarian CancerPanama - Active not recruitingPHASE3
A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis
This study looks at a medicine called ocrelizumab for people with progressive multiple sclerosis (PMS). It aims to see how well it works and if it's safe. Everyone in the study will receive the medicine, and doctors will watch their progress closely.
Progressive Multiple Sclerosis (PMS)Panama - Active not recruitingPHASE1
A Safety, Tolerability, and Immunogenicity Study of mRNA-1345 and mRNA-1365 in Participants Aged 5 Months to <24 Months
This study is testing new mRNA vaccines against common winter viruses, RSV and hMPV, in babies and toddlers aged 5 to 24 months. Researchers want to see if the vaccines are safe and good at triggering the body's immune response.
Respiratory Syncytial VirusHuman MetapneumovirusPanama - RecruitingPHASE1
A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)
This study is testing a new drug called Calderasib, alone or with other treatments, for advanced cancers with a specific gene change (KRAS G12C). It's looking at how safe and effective these treatments are.
Advanced Solid TumorsPanama - Active not recruitingPHASE3
A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)
This study is looking at a new combination of medicines, belrestotug and dostarlimab, for people with a certain type of lung cancer that hasn't been treated before. It compares this combination to a standard treatment (pembrolizumab) and a dummy drug (placebo).
Lung Cancer, Non-Small CellPanama - Active not recruitingPHASE2
Phase 2b Study of GSK4532990 in Adults With NASH
This study is testing a new medicine, GSK4532990, for people with a serious liver condition called Non-Alcoholic Steatohepatitis (NASH). We want to see if this medicine can improve liver damage and inflammation compared to a dummy medicine.
Nonalcoholic Fatty Liver DiseaseNon-alcoholic Fatty Liver DiseasePanama - Recruiting
Exploring the hidden burden of living with Glanzmann thrombasthenia
This study wants to hear from people living with Glanzmann thrombasthenia (GT) and their caregivers. We want to understand the daily challenges and feelings of those affected. Your stories can help improve support and understanding for everyone with GT.
Glanzmann thrombastheniaPanama - Active not recruitingPHASE3
Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients
This study is looking at a new medicine called crizanlizumab to see if two different doses can help teenagers and adults with sickle cell disease. We want to find out if it's safe and if it can reduce pain crises (VOCs) compared to a dummy medicine (placebo).
Sickle Cell Disease (SCD)Panama - Active not recruitingPHASE3
A Study to Investigate the Safety and Efficacy of mRNA-1403 in Participants ≥18 Years of Age for the Prevention of Acute Gastroenteritis
This study is testing a new vaccine (mRNA-1403) to see if it can prevent severe stomach flu, especially the kind caused by norovirus. It will also check how safe the vaccine is and if it causes side effects in adults aged 18 and over.
Acute GastroenteritisNorovirus Acute GastroenteritisPanama - Active not recruitingPHASE2
Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure)
This study is checking if the benefits of bepirovirsen for Hepatitis B last over time. It's for people who previously took part in a bepirovirsen trial and showed good results. No new treatment is given in this follow-up study, just monitoring.
Hepatitis BPanama - RecruitingPHASE1
A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD)
This study is testing a new drug, Ris-Rez, for people with advanced cancers. Researchers want to see if it's safe, how it works, and if it can help stop cancer growth, both alone and with other medicines.
NeoplasmsPanama - Active not recruitingPHASE2
A Study of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus in Pregnant Women and in Infants Born to Vaccinated Mothers
This study is looking at a new vaccine (mRNA-1345) for Respiratory Syncytial Virus (RSV) in pregnant women. It checks if the vaccine is safe and works well for mums-to-be, and also for their babies after they are born.
Respiratory Syncytial VirusPanama - RecruitingPHASE1, PHASE2
A Study of Mocertatug Rezetecan in Combination With Anti-cancer Therapies for Advanced Solid Tumors (BEHOLD-2)
This study looks at a new drug, Mo-Rez, combined with other cancer treatments for advanced solid tumours – cancers that have spread. We want to see how safe and effective this combination is for people whose current treatments aren't working or who can't tolerate them.
Tumours, GynecologicalPanama - RecruitingPHASE3
A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease
This study looks at a new treatment called belimumab for a lung condition called interstitial lung disease (ILD). ILD makes lungs stiff and is often linked to conditions like lupus. We want to see if belimumab can help stabilise or improve lung health and symptoms.
Lung Diseases, InterstitialPanama - Active not recruitingPHASE2
A Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansine Alone or in Combination With Other Anti-Cancer Therapy in One of the Parent Studies
This study is for people with cancer that has spread, who are already benefiting from a specific medicine called trastuzumab emtansine (T-DM1) or other similar treatments in an earlier study. It allows them to keep receiving these important treatments for longer to see if they continue to help.
Neoplasm MetastasisPanama