Latest studies
- Active not recruitingPHASE3
A Long-Term Safety Study of PTC923 in Participants With Phenylketonuria
This study looks at the long-term safety of a new medicine, PTC923, for people with Phenylketonuria (PKU). It also checks if the medicine helps people eat more varied foods by seeing if their usual diet and protein intake change over time.
PhenylketonuriaSlovenia - Not yet recruiting
Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation
This study is testing new ultrasound methods to better understand heart failure in people with atrial fibrillation. It aims to improve how doctors measure pressure in the heart, leading to better diagnosis and treatment, and help predict who might be at higher risk.
Heart Failure (HF)Atrial Fibrillation (AF)Slovenia - Active not recruitingPHASE2, PHASE3
Trial of Preoperative Therapy for Gastric and Esophagogastric Junction Adenocarcinoma
This study is looking at better ways to treat stomach cancer. It compares giving chemotherapy with or without radiotherapy before surgery to see which approach works best for patients whose cancer can be removed with an operation.
Gastric CancerSlovenia - RecruitingPHASE3
A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP
This study compares a new medicine, empasiprubart, with standard IVIg treatment for adults with CIDP. It looks at how well they work and if they are safe. Participants will receive one of these treatments, or a dummy treatment, for several months.
Chronic Inflammatory Demyelinating PolyneuropathyCIDPCIDP - Chronic Inflammatory Demyelinating PolyneuropathySlovenia - RecruitingPHASE3
Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder
This study, called Beeline, is looking at a new medicine called radiprodil for children and young people with a condition called GRIN-related neurodevelopmental disorder (GRIN-NDD). It wants to see if the medicine helps with seizures and other symptoms, and if it's safe.
GRIN-related Neurodevelopmental DisorderSlovenia - Active not recruitingPHASE3
A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Crohn's Disease Who Completed the Studies M14-431 or M14-433
This study looks at a new medicine called upadacitinib for adults with Crohn's disease. It checks how well it works and if it's safe over a long time for people who have already started treatment in previous studies. The aim is to see if it can help manage Crohn's.
Crohn's DiseaseSlovenia - Active not recruitingPHASE3
A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow
This study looks at a new weekly medicine, somapacitan, for children who need help growing. It compares it to Norditropin®, a daily medicine already used. The study includes children born small, or with Turner, Noonan syndrome, or unexplained short stature, over up to 5.5 years.
SGA, Turner Syndrome, Noonan Syndrome, ISSSlovenia - Active not recruitingPHASE3
A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Ulcerative Colitis
This study looks at how well a medicine called risankizumab works and how safe it is for people with ulcerative colitis. It's for those who have already shown improvement with this medicine in a previous study.
Ulcerative Colitis (UC)Slovenia - RecruitingPHASE3
A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy
This study looks at a new medicine called mezagitamab for a kidney problem called IgA nephropathy. It compares mezagitamab to a dummy medicine to see if it lowers protein in the urine and helps protect kidneys. All adults over 18 with this condition can take part.
Kidney DiseaseSlovenia - RecruitingPHASE2, PHASE3
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
This study looks at a new way to treat children and teenagers with a type of blood cancer called Acute Lymphoblastic Leukaemia (ALL). It compares standard treatment with a new approach using chemotherapy instead of radiation, aiming to reduce long-term side effects.
Acute Lymphoblastic LeukaemiaSlovenia - Active not recruitingPHASE3
A Study to Compare Safety and Efficacy of High Doses of Eteplirsen in Participants With Duchenne Muscular Dystrophy (DMD) (MIS51ON)
This study is looking at higher doses of a medicine called eteplirsen for boys with Duchenne muscular dystrophy (DMD). It's checking if these higher doses are safe and work better than the usual dose to help manage the condition.
Muscular Dystrophy, DuchenneSlovenia - Not yet recruiting
Validation of the European Oncology Quality of Life Toolkit
This study is testing a new set of online surveys called the EUonQoL-Kit. These surveys help understand the quality of life for people with cancer at different stages – during treatment, after treatment, and in palliative care. The goal is to make sure the surveys are accurate and helpful across Europe.
CancerSurvivorshipPalliative CareSlovenia - Active not recruitingPHASE3
A Study Evaluating Physical Activity and Joint Health in Severe Haemophilia A Patients ≥12 Years Treated Once Weekly With Efanesoctocog Alfa
This study is looking at how a new medicine, efanesoctocog alfa, affects physical activity and joint health in people aged 12 and over with severe haemophilia A. Participants will use a special activity tracker and diary.
Hemophilia A, SevereSlovenia - RecruitingPHASE3
A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
This study is testing a new drug, giredestrant, against a standard treatment for advanced breast cancer. It's for people whose cancer has grown resistant to previous hormone therapy, to see if giredestrant, combined with other drugs, works better and is safe.
Estrogen Receptor-Positive, HER2-Negative Advanced Breast CancerSlovenia - RecruitingPHASE3
Neoadjuvant Darovasertib in Primary Uveal Melanoma
This study is looking at a new medicine called darovasertib for people with a type of eye cancer called uveal melanoma. We want to see if taking darovasertib before standard treatments like radiation or surgery can help improve outcomes. It's a large study involving many hospitals.
Uveal MelanomaSlovenia - RecruitingPHASE2, PHASE3
An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma
This study aims to improve treatment and understanding of childhood ependymoma. It involves different treatment approaches, including chemotherapy and radiotherapy, for children and young adults up to 22 years old. The goal is to find better ways to help these patients.
Childhood EpendymomaSlovenia - Active not recruitingNA
Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer
This study aims to understand if temporarily stopping hormone therapy for early breast cancer to allow for pregnancy is safe. It will also look at fertility and emotional well-being for young women.
Early Breast CancerSlovenia - Active not recruitingPHASE2
A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis
This study looks at new ways to treat ulcerative colitis, a condition causing gut inflammation. We're testing a combination of medicines (JNJ-78934804) for people whose current treatments aren't working well. The goal is to see if these new approaches are safe and effective.
Colitis, UlcerativeSlovenia - RecruitingPHASE1, PHASE2
FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma
This study, FaR-RMS, is for children and adults with a type of cancer called rhabdomyosarcoma. It's looking for better ways to treat both newly diagnosed and returning cancer, using different combinations of medicines and radiotherapy.
RhabdomyosarcomaSlovenia - Active not recruiting
Evaluating Effectiveness and Long Term Safety of Damoctocog Alfa Pegol in Patients, Who Have Been Diagnosed With Hemophilia A
This study looks at how a medicine called Jivi (damoctocog alfa pegol) works for people with haemophilia A in their daily lives. It checks its long-term safety and how happy patients and doctors are with it.
Hemophilia ASlovenia - RecruitingPHASE3
A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast
This study looks at a long-term treatment called nerandomilast for people with pulmonary fibrosis. It's for those who've used it in a past study. We'll see how safe and effective it is over time, checking if it helps lung function and slows down the disease.
Idiopathic Pulmonary FibrosisProgressive Pulmonary FibrosisSlovenia - Recruiting
COVID-19 Vaccines Safety Tracking (CoVaST)
This study is looking at the side effects of COVID-19 vaccines in different groups of people, like healthcare workers and older adults. It aims to understand common side effects, who is more likely to get them, and any long-term effects. This helps build trust in vaccines.
Adverse Reaction to VaccineCOVID19 VaccineSlovenia - RecruitingPHASE3
High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)
This study looks at new ways to treat high-risk neuroblastoma, a type of cancer, in children and young people. Researchers are testing different combinations of chemotherapy and radiation to find the most effective treatments to help patients live longer and healthier lives.
High-Risk NeuroblastomaPatient With Insufficient Response ChemoimmunotherapySlovenia - Active not recruiting
Study to Learn More About the Safety of Drug Jivi Over a Long Period of Time in Previously Treated Patients With Hemophilia A (Bleeding Disorder Resulting From a Lack of FVIII) Who Are Receiving Jivi Regularly at Their Treating Doctors to Prevent Bleeding
This study looks at how safe a medicine called Jivi is for people with haemophilia A over a long time. It checks patients who are already using Jivi to prevent bleeding, gathering information during their regular doctor visits.
Hemophilia ASlovenia - Active not recruiting
Long-Term Observational Study on Effectiveness and Safety of Lecigon in Patients With Advanced Parkinson's Disease
This study looks at how a medicine called Lecigon® works and its safety for people with advanced Parkinson's disease in their everyday lives. It gathers information from around 300 patients who are already using Lecigon® to help manage their symptoms that aren't well controlled by other treatments.
Advanced Parkinson DiseaseSlovenia - Recruiting
Trifecta-Kidney cfDNA-MMDx Study
This study looks at new ways to check for rejection in kidney transplant patients. It compares a new blood test (DD-cfDNA) with a special biopsy test (MMDx) and traditional checks to see which is best at finding rejection accurately.
Kidney Transplant RejectionSlovenia - Enrolling by invitation
A Study Following Males With Haemophilia A on Prophylaxis With Esperoct®
This study looks at how well Esperoct® works and if it has side effects for men and boys with haemophilia A. Participants will receive their usual treatment and share information about their health over several years.
Haemophilia ASlovenia - Active not recruitingPHASE3
RT or No RT Following Chemotherapy in Treating Patients With Stage III/IV Hodgkin's Disease
This study looks at whether adding radiation after chemotherapy helps people with advanced Hodgkin's disease. Researchers want to see if this combination prevents the disease from coming back or helps people live longer, compared to chemotherapy alone.
LymphomaSlovenia - Not yet recruitingPHASE3
International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 (IntReALL BCP 2020)
This study is looking at new ways to treat a type of childhood leukaemia called B-Cell Acute Lymphoblastic Leukaemia (ALL) when it comes back. It aims to use kinder, more targeted treatments instead of strong chemotherapy.
B-Cell Acute Lymphoblastic LeukaemiaSlovenia - Not yet recruitingNA
Urinary Proteomics Combined With Home Blood Pressure Telemonitoring for Health Care Reform
This study looks at new ways to predict heart and kidney problems in people aged 55-75. It combines checking blood pressure at home with a urine test. Researchers want to see if this combination helps doctors treat and prevent these conditions more effectively and affordably.
Protein DeregulationBlood PressureHealth Care UtilizationCost EffectivenessSlovenia - Active not recruitingPHASE3
Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib
This study is for people with ovarian or breast cancer who are already receiving olaparib in a different study and are still benefiting. It allows them to continue getting their treatment if their current study ends, ensuring they keep receiving a medication that is helping them.
Ovarian CancerBreast CancerSlovenia - Recruiting
Defects of Keratinocytes Function in Dermatologic Patients
This study looks at a skin condition called hidradenitis suppurativa (HS). Researchers want to understand how tiny skin cells called keratinocytes work when someone has HS. They hope this will lead to better treatments for HS, an often painful and challenging long-term condition.
Hidradenitis SuppurativaSlovenia - RecruitingPHASE3
Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
This study is testing a new medicine, Masitinib, for people with Motor Neurone Disease (ALS). It aims to see if Masitinib, when taken with the usual medicine Riluzole, can help slow down the disease compared to taking Riluzole with a dummy pill.
Amyotrophic Lateral SclerosisSlovenia - Active not recruitingPHASE2
A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML
This study is testing a new combination of treatments for children and teenagers with a certain type of acute myeloid leukemia (FLT3-mutated AML). It combines a drug called midostaurin with standard chemotherapy to see if it's safe and effective for these patients.
FLT3-mutated Acute Myeloid LeukemiaSlovenia - RecruitingNA
Prehospital Resuscitation Intranasal Cooling Effectiveness Survival Study 2
This study looks at whether very early cooling, started by paramedics, can help people who have had a sudden heart stoppage outside of hospital. We want to see if it improves survival and brain recovery compared to keeping body temperature normal.
Out-Of-Hospital Cardiac ArrestHypothermiaVentricular FibrillationSlovenia - RecruitingPHASE3
A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)
This study is testing a new medicine, nipocalimab, to see if it can help prevent a serious blood condition called FNAIT in babies. FNAIT can cause low platelet counts in newborns, which can lead to bleeding problems. Researchers want to know if nipocalimab is effective and safe.
Thrombocytopenia, Neonatal AlloimmuneSlovenia - Active not recruitingPHASE3
A Study of Guselkumab in Participants With Active Psoriatic Arthritis
This study is looking at a new medicine called guselkumab for people with psoriatic arthritis. It aims to see how well it reduces pain, swelling, and other symptoms compared to a dummy treatment, and if it helps improve their condition.
Arthritis, PsoriaticSlovenia - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A phase 3b open-label, multicenter study evaluating physical activity and joint health in previously treated patients ≥12 years of age with severe haemophilia A treated with intravenous recombinant coagulation factor VIII Fc-von Willebrand Factor-XTEN fusion protein (rFVIIIFc-VWF-XTEN; efanesoctocog alfa) for 24 months
This study is looking at a new treatment called efanesoctocog alfa for severe haemophilia A. It aims to see how it affects physical activity and joint health in patients aged 12 and over, comparing results over 24 months. It's a key step in understanding if this medicine helps people live more active lives.
Haemophilia ASlovenia - RecruitingNA
LANDMARK Trial: a Randomised Controlled Trial of Myval THV
This study, called the LANDMARK Trial, is looking into how safe and effective a new heart valve called Myval THV is. It's compared to existing valves for people with a common heart condition called aortic valve stenosis. The goal is to see if it works just as well.
Aortic Valve StenosisSlovenia - Active not recruitingPHASE3
Comparison Between ABP 692 and Ocrevus® (Ocrelizumab)
This study compares a new medicine, ABP 692, with an existing one, Ocrevus, for people with a type of multiple sclerosis (RRMS). It checks if special brain scans and how the medicines act in the body are similar, aiming to offer another treatment option.
Relapsing-remitting Multiple Sclerosis (RRMS)Slovenia - Active not recruitingPHASE3
A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With Multifocal Motor Neuropathy
This study looks at a new medicine called empasiprubart compared to a standard treatment, IVIg, for adults with a rare muscle condition called Multifocal Motor Neuropathy (MMN). It aims to see if empasiprubart is safe and works well.
Multifocal Motor Neuropathy (MMN)MMNSlovenia - Active not recruitingPHASE3
Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin's Lymphoma
This study looks at different chemotherapy treatments, with or without radiation, for Hodgkin's lymphoma. Researchers want to find the best way to treat this cancer, making sure treatments are effective while reducing side effects.
LymphomaSlovenia - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Randomized, 24-week, Placebo-controlled, Double-blind Study to Assess the Efficacy, Safety, and Tolerability of Rocatinlimab (AMG 451) in Combination With Topical Corticosteroids and/or Topical Calcineurin Inhibitors in Adult Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-SHUTTLE)
This study is looking into a new treatment called rocatinlimab for adults with moderate to severe eczema. It wants to see if this new medicine, when used with usual eczema creams, can help clear up skin and reduce itching compared to a dummy treatment.
Atopic DermatitisSlovenia - Ongoing, recruitingTherapeutic use (Phase IV)
An 18-month low-interventional prospective, multicentre study to assess joint outcomes in patients with haemophilia A or B on prophylaxis with efmoroctocog alfa or eftrenonacog alfa
This study looks at how well different medicines (Elcocta and Alprolix) help people with haemophilia A or B protect their joints. Researchers will follow participants for 18 months to see if these treatments prevent joint problems.
Hemophilia A and BSlovenia - Ongoing, recruitingPhase II and Phase III (Integrated)
A Phase 2/3 Study of Navtemadlin as Maintenance Therapy in Subjects with TP53WT Advanced or Recurrent Endometrial Cancer Who Responded to Chemotherapy
This study looks at a new drug, Navtemadlin, for women with advanced endometrial cancer. It's for those who responded well to previous chemotherapy. The aim is to see if Navtemadlin can help keep the cancer from coming back for longer.
Advanced or Recurrent Endometrial CancerSlovenia - Ongoing, recruitingTherapeutic exploratory (Phase II)
EORTC 2120-HNCG: Radiotherapy plus xevinapant or placebo in older patients with locally advanced head and neck squamous cell carcinoma: a randomized phase II study (Ravina)
This study looks at a new drug, xevinapant, given with radiotherapy for older patients with advanced head and neck cancer. We want to see if this combination helps more people live longer without their cancer coming back. It's a Phase II study, meaning we're testing its effectiveness and safety.
Squamous cell carcinoma of head and neckSlovenia - Ongoing, recruitingTherapeutic confirmatory (Phase III)
Efficacy and safety of co-administered cagrilintide and semaglutide (CagriSema) s.c. in doses 2.4/2.4 mg and 1.0/1.0 mg once weekly versus semaglutide 2.4 mg and 1.0 mg, cagrilintide 2.4 mg and placebo in participants with type 2 diabetes inadequately controlled on metformin with or without an SGLT2 inhibitor
This study is testing a new combination medicine, CagriSema, for people with type 2 diabetes. It's looking at whether this combined medicine is better at controlling blood sugar and helping with weight loss than existing treatments, including its individual components, semaglutide and cagrilintide.
Type 2 diabetesSlovenia - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Single Arm, Open Label Multicentre Extension Study to Evaluate the Effectiveness and Safety of Ocrelizumab in Patients with Multiple Sclerosis Previously Enrolled in A F. Hoffmann-La Roche Sponsored Ocrelizumab Phase IIIb/IV Clinical Trial
This study looks at how well a medicine called ocrelizumab works and if it's safe for people with multiple sclerosis (MS). It's for patients who have already been in similar studies with the same medicine.
Multiple sclerosis (MS)Slovenia - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Randomized Study of Andexanet Alfa Compared to Usual Care in Patients Receiving a Factor Xa Inhibitor who Require Urgent Surgery or Procedure (ANNEXA-RS)
This study is comparing a new medication called Andexanet Alfa to usual care. It's for patients who are taking blood thinners (like apixaban, rivaroxaban, or edoxaban) and need urgent surgery. The aim is to see if Andexanet Alfa helps stop bleeding during their operation.
Reversal of anticoagulation effect in patients on a FXa inhibitor (apixaban, rivaroxaban, or edoxaban) who require urgent surgery or procedure, and who have a major risk of bleeding.Slovenia - Ongoing, recruitingPhase III and phase IV (Integrated)
Effects of single-pill combination of telmisartan/amlodipine and telmisartan/amlodipine/hydrochlorothiazide on 24-hour blood pressure (BP) reduction, 24-h BP variability and office BP control in patients with arterial hypertension – SATELLITE
This study looks at how new combination medicines affect high blood pressure over 24 hours. Researchers want to see how well these pills lower blood pressure and keep it steady throughout the day in people with high blood pressure.
Arterial hypertensionSlovenia