- Active not recruitingNA
AI-enhanced LF-MRI in Epilepsy
This study is looking at a new, more affordable MRI scan for people with epilepsy. It uses a lower-strength MRI machine and artificial intelligence to see if it can diagnose epilepsy as well as the standard, more expensive scans. We want to help more people get the right diagnosis, especially in areas where advanced scans are hard to find.
For: EpilepsyUnited Kingdom - Recruiting
7T Imaging Pilot-study in Patients With Motor Neuron Disease to Find Non-Invasive Disease Imaging Biomarkers
This study uses a super-powerful MRI scanner to look at the brains of people with Motor Neuron Disease (MND). The goal is to find new ways to diagnose MND earlier and more accurately, helping patients get the right care and join trials sooner. It’s a small pilot study to see if this new scan works well.
For: ALS - Amyotrophic Lateral SclerosisUnited Kingdom - RecruitingNA
MSOT and MRI for Non-invasive Assessment of Intestinal Transit Time in Children With Chronic Bowel Emptying Disorders
This study in Erlangen, Germany, is looking for children aged 0-17 with long-term bowel emptying problems and healthy adults. It uses new, radiation-free scanning methods (MSOT and MRI) to understand how food moves through the gut. The aim is to find better ways to diagnose and treat constipation.
For: Chronic Constipation · Slow Transit Constipation · Intestinal Transit DisorderGermany - RecruitingNA
Descriptive Study of the Reconstruction of Osteochondral Lesions of the Knee: Clinical and Imaging Results
This study looks at how well different treatments work for knee cartilage problems. Researchers are checking how patients feel and what MRI scans show after surgery to fix damaged knee cartilage using the patient's own tissue or a special material.
For: Osteochondral DefectFrance - Recruiting
Optimization of Sequences to Improve the Quality and Comfort of the Magnetic Resonance Imaging Examination
This study looks at how to make MRI scans better and more comfortable. Researchers are testing new ways of doing MRI scans to see if they can improve the image quality and patient experience. If you take part, you might have a slightly longer scan and receive a gift voucher.
For: Optimized MRI SequencesFrance - Not yet recruitingNA
Investigating Proprioceptive Impairment in Adolescents With Idiopathic Scoliosis (AIS) (SCOLIO-PROPRIO)
This study looks at whether teenagers with severe scoliosis have trouble sensing their body's position. Researchers will use special brain scans (MRIs) to see if these body-sensing issues are linked to changes in the brain or uneven back muscles. Understanding this could help develop new treatments.
For: Scoliosis Idiopathic AdolescentFrance - RecruitingNA
Cohort of STEMI Patients 2
This study looks at how heart attacks (STEMI) affect people. Researchers want to understand better why they happen, how treatments work, and how people's lives change afterwards. They hope to find new ways to help people who have had a heart attack.
For: Myocardial InfarctionFrance - Active not recruitingNA
My Personalized Breast Screening
This study, called MyPeBS, is looking at new ways to check for breast cancer. It's comparing standard breast screening with a more personalised approach, based on your individual risk, aiming to find cancers earlier and see which method works best over 4 years, with longer follow-up.
For: Breast ScreeningBelgium · France · Israel - RecruitingPHASE4
Temporal Characterization of Extracellular Vesicles During Cellular Therapy Using CAR-T Cells and During the Occurrence of Immune Effector Cell-Associated Neurotoxicity Syndrome
This study looks at how CAR-T cell treatment affects the brain and blood. Researchers want to understand a side effect called ICANS, where the brain can be affected. They're studying tiny particles in the blood to find ways to prevent and treat this issue.
For: Immune Effector Cell Associated Neurotoxicity SyndromeFrance - RecruitingNA
REward SYSTem in Autism Spectrum Disorder and Addictive Disorder
This study looks at how the brain's 'reward system' works in people with autism and those with food addiction, compared to healthy volunteers. We use special brain scans (MRI and EEG) to understand more about these conditions and how they might be linked in the brain.
For: Autism Spectrum DisorderFrance - RecruitingNA
Imaging in Moyamoya Disease - Study to Investigate Different Imaging Technologies for a Better Understanding of Various Imaging Techniques to Evaluate Cerebral Hemodynamics, Disease-activity and Possibly the Etiology in Moyamoya Patients
This study aims to improve how Moyamoya disease is diagnosed and monitored using different scanning techniques like MRI. Researchers want to better understand how the disease progresses and find new ways to help patients by making imaging more effective.
For: Moyamoya Disease · MoyamoyaGermany - RecruitingNA
MRI Screening of Placenta Adhesion Abnormalities
This study looks at using a special type of MRI scan to find problems with how the placenta attaches during pregnancy. It aims to see if this new MRI method is better at spotting these issues than current scans, helping doctors plan safer deliveries for mums.
For: Placenta; ImplantationFrance - Active not recruitingNA
MRI Screening of Second Primary Cancer Occurring Within Radiation Fields After Treatment by External Beam Radiation Therapy for Hereditary Retinoblastoma (DepiSCARRH)
This study looks at whether regular MRI scans can find new cancers early. It's for people who had a type of eye cancer called retinoblastoma as a child and were treated with radiation. The aim is to see if early detection leads to better outcomes.
For: Hereditary RetinoblastomaFrance - Recruiting
PRostate Cancer Enhanced Diagnosis by Calibration Technology
This study is developing a new tool to improve how prostate cancer is found using MRI scans. It aims to make MRI results more consistent and accurate by using special mats and software to calibrate the scans, helping doctors better plan for biopsies.
For: Prostate CancersUnited Kingdom - RecruitingPHASE2
Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations
This study looks at how well a medicine called rapamycin treats lymphatic malformations in children's faces and necks. Researchers want to see if it can shrink these growths, improve quality of life, and reduce bleeding over six months.
For: Lymphatic Malformation · PediatricFrance - Recruiting
SupraScapular Cuff Study: Assessing the Effects of Size and Type of Rotator Cuff Tear on Suprascapular Nerve Function
This study looks at how the size and type of shoulder tendon tears (rotator cuff) affect a nearby nerve (suprascapular nerve). We're trying to understand if tears damage this nerve and if surgery can help it recover. It also aims to see what factors might protect the nerve.
For: Orthopedic DisorderUnited Kingdom - RecruitingNA
Reproducibility of Multiparametric Renal Magnetic Resonance Imaging on 1.5T MRI Scanners
This study looks at how well a special type of MRI scan, called renal MRI, consistently shows kidney information on common 1.5T scanners. We're testing if the results are similar each time and across different scanners, and also comparing them to scans done on stronger 3T machines.
For: Multiparametric MRIDenmark · Germany · Italy - Recruiting
MEMRI and Kidney Disease
This study uses a special MRI scan to look at how kidney injury, kidney transplants, and other kidney problems affect your heart. Researchers want to find a new way to identify people at risk of heart problems and ongoing kidney disease, helping them get treatment earlier.
For: Acute Kidney Injury · Kidney Transplant · VasculitisUnited Kingdom - Not yet recruiting
MRinRT: Swansea University and SWWCC Collaboration Study.
This study looks at using MRI scans to make radiotherapy for cancers like brain, stomach, and gullet cancer more accurate. It aims to see if MRI can help doctors better plan and adjust treatment, potentially reducing side effects.
For: Carcinoma · Glioblastoma · RadiotherapyUnited Kingdom - Recruiting
MRI Assessment of Pulmonary Edema in Acute Heart Failure
This study uses MRI scans to get a clearer picture of how much fluid is in the lungs of people with sudden heart failure. Researchers want to see how this fluid changes during hospital stay and if these measurements can predict future health risks.
For: Acute Heart Failure · Pulmonary Edema With Heart FailureCanada - RecruitingNA
Cerebral and Cognitive Impact of Professional Soccer Practice
This study looks at how professional football (soccer) might affect the brains of players. We're using special body scans (MRIs) to see if repeated minor head knocks lead to changes in the brain and thinking skills in players at the end of their career, compared to other athletes.
For: Traumatic Chronic EncephalopathyFrance - Not yet recruitingPHASE3
Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS : Therapies Withdrawal IN Relapsing Multiple Sclerosis)
This study looks at whether people aged 55 and over with stable relapsing-remitting MS can safely stop their MS medication. It compares continuing treatment to stopping, checking MS activity, quality of life, and disability over two years.
For: Relapsing-remitting Multiple Sclerosis (RRMS)France - Recruiting
Lung MRI in Paediatric Lung Disease: MRI in PBB
This study looks at a new, safe MRI scan for children aged 5-17 with a long-lasting wet cough, called Protracted Bacterial Bronchitis (PBB). It uses a special gas to find problems in their lungs early, hoping to improve treatment and reduce antibiotics.
For: Protracted Bacterial BronchitisUnited Kingdom - RecruitingNA
Characterization of New Phenotypes of Patients With Spinal Muscular Atrophy Treated With SMN Restoring Therapy
This study looks at children under 16 with Spinal Muscular Atrophy (SMA) who are receiving new treatments. We want to understand how these treatments are changing the disease and find the best ways to check on patients' health and progress.
For: Spinal Muscular AtrophyFrance - Not yet recruitingNA
Study of Concordance Between Inflammatory Activity Assessed by Enteric MRI With and Without Intestinal Distension Product in Patients With Ileal Crohn's Disease.
This study looks at a new way to do MRI scans for Crohn’s disease. It compares scans with and without a special drink, to see if we can still get good information about inflammation without patients having to drink something that can cause uncomfortable side effects.
For: Crohn Disease (CD)France - RecruitingNA
Investigation of AlzHeimer's Predictors in Subjective Memory Complainers - Extension Study
This study is looking into how Alzheimer's disease develops in people who have noticed changes in their memory. It involves following people who were part of a previous study for several more years to see if they develop Alzheimer's.
For: Alzheimer Disease · Memory Complaint · Memory DisordersFrance - RecruitingNA
Understanding the Mechanisms of Autism : an MRI and Social Cognition Study
This study uses brain scans and eye-tracking to understand how autism affects the brain and social skills. We're looking at children and young people with autism and those without. The goal is to find better ways to understand and monitor autism.
For: Autism Spectrum DisorderFrance - RecruitingNA
Child Cognitive-Affective Resilience Following 13-11 Event : A Pluridisciplinary Study of Intergenerational Transmission of a Traumatic Event
This study looks at how highly stressful events can affect families over generations. It brings together experts to understand how trauma is passed on, both biologically and behaviourally, from parents to children, using different assessments.
For: Intergenerational TraumaFrance - Active not recruitingPHASE3
Phase 3, Multicenter, Randomized Study, Evaluating the Efficacy and Tolerability of Focused HIFU (High Intensity Focused Ultrasound) Therapy Compared to Active Surveillance in Patients With Significant Low Risk Prostate Cancer
This study is looking at a new way to treat early-stage prostate cancer called HIFU. It compares this focused ultrasound treatment to simply watching the cancer closely. We want to see if HIFU can destroy the cancer without the severe side effects of traditional surgery, offering a kinder treatment option.
For: Prostate CancerFrance - Not yet recruitingNA
Advanced Diffusion Magnetic reSonance Prostate Imaging for Reducing Extraneous Biopsies (ASPIRE) - Calibration Component (Multi-centre Scanner Calibration) and Validation Component (Multi-centre Validation)
This study looks at new MRI scans for prostate cancer. We want to find out if these advanced scans can help doctors decide who really needs a biopsy, to avoid unnecessary procedures and their risks.
For: Prostate Cancer (Diagnosis)United Kingdom - Active not recruiting
Central Vein Sign: a Diagnostic Biomarker in Multiple Sclerosis
This study looks at a new MRI technique called the Central Vein Sign (CVS) to see if it can help doctors diagnose Multiple Sclerosis (MS) more accurately and earlier. It aims to improve diagnosis for various types of MS presentations.
For: Multiple SclerosisUnited States · Canada - RecruitingPHASE2
Nivolumab in Children and Adults With Nasopharyngeal Carcinoma
This study is looking at adding a new drug called Nivolumab to standard chemotherapy for nasopharyngeal cancer. It aims to see if this combination helps more patients achieve a complete response, meaning the cancer is no longer detectable, especially when seen on scans.
For: Nasopharyngeal Carcinoma · Nasopharyngeal Cancer · Nasopharyngeal NeoplasmsGermany - Active not recruiting
Myotonic Dystrophy - Vascular and Cognition
This study looks at how myotonic dystrophy type 1 affects the brain and thinking skills. Researchers want to see if problems with sugar processing, like diabetes, are linked to memory and planning difficulties in people with this condition. They will use brain scans and thinking tests to find out more.
For: Myotonic Dystrophy 1 · Diabetes · Carbohydrate IntoleranceFrance - RecruitingNA
The preSPG4 Study - Studying the Prodromal and Early Phase of SPG4
This study looks at people who might get Hereditary Spastic Paraplegia (SPG4) or are in its early stages. We want to understand how the condition develops over time, even before symptoms appear, to find better ways to help in the future.
For: Hereditary Spastic Paraplegia · Hereditary, Spastic Paraplegia, Autosomal DominantGermany - RecruitingPHASE3
Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging.
This study compares a new sound wave scan (micro-ultrasound) with the current standard (MRI) for checking the prostate gland in men aged 50-70. It aims to see if the new scan is as good at finding problems, to help decide if a biopsy is needed.
For: Prostate Cancer ScreeningUnited States · Canada · France - RecruitingNA
Eye Imaging for the Study of Childhood Myopia
This study looks at children's eyes to understand why some respond better to treatments for short-sightedness (myopia). Researchers will use eye scans and measurements to learn more about eye shape, hoping to make treatments work better for each child.
For: Hyperopia and MyopiaFrance - Recruiting
UK Imaging Diabetes Study Seeing Diabetes Clearly
This study looks at how Type 2 Diabetes affects different body organs using special MRI scans. We want to see if these scans can help predict future health problems in people with diabetes who haven't had heart issues before. It involves a single MRI scan and a few other checks over 5 years.
For: Type2 DiabetesUnited Kingdom - Active not recruitingNA
Renal Tumour Imaging Using MRI
This study looks at new MRI scans for kidney tumours. We want to see if these scans can tell us what type of kidney tumour someone has before surgery. This could help doctors decide the best treatment, avoiding unnecessary procedures for harmless tumours.
For: Renal Cancer · MRI · Small Renal MassUnited Kingdom - Not yet recruiting
The Oswestry Metabolic BONE Cohort
This study looks at how conditions like osteoporosis, obesity, and diabetes affect bone health and fracture risk. Researchers use information from regular patient care, including scans and health records, to better understand and predict broken bones, helping improve treatments.
For: OsteoporosisUnited Kingdom - Recruiting
Understanding Beta Cell Disorders Through the Study of Rare Genotypes (ENDURE)
This study, called ENDURE, wants to understand how rare changes in our genes affect cells that control blood sugar. We're looking for people with and without these gene changes to help us learn more about diabetes and other sugar-related conditions, hoping to find new ways to help patients.
For: Diabetes Mellitus · Monogenic Diabetes · HyperinsulinismUnited Kingdom