A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

To join this study, you would need to be at least 18 years old. You should have a Body Mass Index (BMI) of 27 or higher, which indicates you are overweight or have obesity. It's also important that you've tried to lose weight with diet changes before, but haven't been successful.

Crucially, you must have been diagnosed with type 2 diabetes. Your recent blood test (HbA1c) for diabetes control needs to be within a specific range, showing your diabetes is not too well controlled but also not extremely high. You cannot have type 1 diabetes or other specific types of diabetes.

There are also some reasons why you might not be able to join. For example, if your weight has changed a lot in the last three months, if you have certain kidney problems, or if you've had pancreatitis. Also, if you're allergic to similar medications called GLP-1 RAs, or if you or a close family member has a history of certain thyroid cancers (medullary thyroid carcinoma) or a condition called MEN type 2, you wouldn't be able to participate. You also can't be in another clinical trial at the same time.

If you are eligible and choose to take part, you would be randomly assigned to either receive the new ASC30 tablet or a dummy pill (placebo). This means neither you nor the study team will know which one you are taking. You'll take your assigned tablet once a day.

You would have regular visits to the study clinic for check-ups, blood tests, and other assessments to monitor your health, how the treatment is working, and any side effects. The total length of the study isn't specified here, but Phase 3 trials often run for several months to a couple of years to properly assess long-term effects. You would be given clear instructions on your medication, diet, and what to expect throughout your time in the study.