Latest studies
- RecruitingPHASE3
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
This study is testing a new medication called Tulisokibart for people with moderate to severe Crohn's disease. Researchers want to see if it's safe and effective in reducing symptoms and improving the gut lining. It involves different ways of giving the medicine compared to a dummy treatment.
Crohn's DiseaseFinland - RecruitingPHASE2
Pan Tumor Rollover Study
This study looks at the long-term safety of different cancer treatments, including nivolumab, alone or combined with other medicines. It's for people with various types of cancer who are already receiving treatment in a related study, aiming to see how these treatments work over time.
CancerFinland - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase III, Multicentre, Randomised, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Extension Study to Evaluate the Long-term Efficacy and Safety of Tozorakimab in Participants with Chronic Obstructive Pulmonary Disease (COPD) with a History of Exacerbations (PROSPERO)
This study is testing a new medicine called Tozorakimab for people with severe COPD. It aims to see if Tozorakimab can reduce flare-ups and is safe to use long-term, compared to a dummy medicine.
Chronic Obstructive Pulmonary Disease (COPD)Finland - Ongoing, recruitingPhase II and Phase III (Integrated)
A Phase 2b/3 Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-1654 in Healthy Pre-Term and Full-Term Infants
This study is looking at a new medicine, MK-1654, to help protect babies from a common chest infection called RSV. It will check if the medicine works well and if it's safe for both premature and full-term babies.
Prevention of RSVFinland - Ongoing, recruitingTherapeutic exploratory (Phase II)
A phase 2B, multicenter, randomized, double-blind, placebo-controlled, dose-finding, efficacy and safety study of HRO350 in subjects with mild-to-moderate psoriasis (the ‘HeROPA’ study)
This study is testing a new treatment called HRO350 for people with mild to moderate psoriasis. Researchers want to see if it improves psoriasis symptoms and is safe to use. Some people will get HRO350, others will get a dummy treatment, to compare results over 26 weeks. It's for adults aged 18 and over.
PsoriasisFinland - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Randomized, 24-week, Placebo-controlled, Double-blind Study to Assess the Efficacy, Safety and Tolerability of Rocatinlimab (AMG 451) Monotherapy in Adult Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)
This study is looking at a new medicine called Rocatinlimab for adults with moderate to severe eczema. We want to see if it helps improve skin, reduce itching, and is safe over 24 weeks compared to a dummy medicine.
Atopic DermatitisFinland - Ongoing, recruitingTherapeutic exploratory (Phase II)
Efficacy and tolerability of tasipimidine after 3 repeated bed-time doses in patients with insomnia disorder with a 4-week extension part
This study is testing a new liquid medicine, tasipimidine, to see if it helps people with insomnia sleep better. Researchers are checking how well it works and if it has any side effects, particularly how it affects waking up during the night and how long it takes to fall asleep.
Insomnia disorderFinland - Ongoing, recruitingPhase II and Phase III (Integrated)
Evasayil TM: A placebo-controlled trial to evaluate the efficacy and safety of spesolimab in the treatment of patients with Netherton syndrome
This study is testing a new medicine, spesolimab, for Netherton syndrome. It's a trial where some people get the medicine and others get a dummy treatment (placebo) to see how well spesolimab works and if it's safe. We're looking at how it improves skin symptoms and overall well-being.
Netherton syndrome (NS)Finland - Ongoing, recruitingTherapeutic confirmatory (Phase III)
ISIS 678354-CS9: A Randomized, Double-blind, Placebo-Controlled, Phase 3 Study of Olezarsen (ISIS 678354) in Patients with Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), or with Severe Hypertriglyceridemia
This study is testing a new medicine, Olezarsen, for people with high 'triglycerides' (a type of fat in the blood) and heart problems. It aims to see if the medicine can lower these fats and is safe to use.
Hypertriglyceridemia, Cardiovascular Diseases, AtherosclerosisFinland - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A randomized, parallel-group, double-blind, placebo-controlled, multicenter Phase III trial to evaluate efficacy and safety of secukinumab administered subcutaneously versus placebo, in combination with a glucocorticoid taper regimen, in patients with polymyalgia rheumatica (PMR)
This study is testing a new medicine, secukinumab, for polymyalgia rheumatica (PMR). It compares secukinumab with a dummy treatment (placebo) alongside a common steroid medicine to see if it helps reduce symptoms and allows people to use less steroid medicine.
Polymyalgia RheumaticaFinland - Ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study to characterize the pharmacokinetic profile of norucholic acid (NCA) in patients with primary sclerosing cholangitis (PSC)
This study is looking at how a new medicine, called norucholic acid (NCA), moves through the bodies of people with primary sclerosing cholangitis (PSC). It's an early stage study to understand the medicine better.
Primary Sclerosing Cholangitis (PSC)Finland - Ongoing, recruitingTherapeutic confirmatory (Phase III)
C5721002 _ A Randomized, Open-Label, Phase 3 Trial of Tisotumab Vedotin vs Investigator’s Choice Chemotherapy in Second- or Third-Line Recurrent or Metastatic Cervical Cancer
This study is testing a new drug (Tisotumab Vedotin) for cervical cancer that has come back or spread, and hasn't responded to previous treatments. It compares whether the new drug works better than standard chemotherapy to help people live longer.
Second- or Third-Line Recurrent or Metastatic Cervical CancerFinland - Recruiting
Endovascular AAA Intervention Using the GORE® EXCLUDER® Conformable AAA Endoprosthesis or Iliac Branch Endoprosthesis
This study looks at how well special devices work in real-world patients with a condition called an Abdominal Aortic Aneurysm (AAA). Doctors will watch patients for up to 10 years after they get these devices to see how they're doing and if there are any problems.
AAA - Abdominal Aortic AneurysmFinland - RecruitingPHASE2, PHASE3
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
This study keeps an eye on people who have had a special treatment called gene-modified T-cell therapy for cancer. It aims to check their health and how well the treatment worked over a long time, making sure it's safe and effective.
NeoplasmsFinland - Active not recruiting
NVT ALLEGRA TAVI System TF in Failing Calcified Aortic Heart Valves in a Real-world Patient Population
This study looks at how well a new heart valve replacement called the ALLEGRA TAVI System TF works in people with heart valve problems. It checks their health and quality of life after the procedure, gathering information from real-world patients in the UK.
Transcatheter Aortic Valve ImplantationFinland - Active not recruitingPHASE2
To Assess Efficacy and Safety of Batoclimab in Adult Participants With Active CIDP
This study is testing a new drug called batoclimab for adults with a nerve condition called Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). It aims to see how well it works and if it's safe compared to a dummy drug.
Chronic Inflammatory Demyelinating PolyneuropathyFinland - RecruitingPHASE3
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
This study is testing a new medicine, Opevesostat, for men with prostate cancer that has spread and is resistant to hormone treatment. We want to see if Opevesostat helps men live longer compared to standard hormone therapies, especially after they've had other treatments.
Prostate Cancer MetastaticFinland - Recruiting
Product Surveillance Registry
This study keeps track of how well Medtronic medical devices, like those for heart problems or other conditions, work in real life. It aims to make sure these devices are safe and effective for patients.
Cardiac Rhythm DisordersUrological DisordersNeurological DisordersCardiovascular DisordersFinland - Active not recruitingPHASE3
A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Cancer
This study looks at a new drug, apalutamide, for men with prostate cancer that hasn't spread but is resistant to standard treatment. It aims to see if the drug can stop the cancer from spreading and if it's safe to use.
Prostatic NeoplasmsFinland - Active not recruitingPHASE2
A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study
This study is for men with prostate cancer who are already taking enzalutamide as part of another research study. It aims to gather more information on the long-term safety of enzalutamide when it's helping them. Participants will continue their current treatment and have regular check-ups.
Prostate CancerFinland - RecruitingPHASE3
The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis
This study is looking into a new medicine, BI 1291583, for people with bronchiectasis. It aims to see if this medicine can help reduce flare-ups, which are common with the condition. Participants will take a tablet daily and be monitored for up to 1 year and 8 months.
BronchiectasisFinland - RecruitingPHASE3
Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
This study looks at a new treatment called dostarlimab for certain types of colon cancer that haven't spread. It compares dostarlimab with standard treatments to see if it works better before and after surgery to help patients.
Colonic NeoplasmsNeoplasms, ColonFinland - Active not recruitingPHASE3
Efficacy and Safety of Tezepelumab in Patients With Eosinophilic Esophagitis
This study is looking at a new medicine called Tezepelumab for people aged 12-80 with Eosinophilic Oesophagitis (EoE). It aims to see if regular injections help improve symptoms and is safe, compared to a dummy treatment.
Eosinophilic EsophagitisFinland - RecruitingNA
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
This study compares two common medical devices, the Medtronic Endurant and Gore Excluder, used to treat a condition called Abdominal Aortic Aneurysm (AAA). It aims to see how well they shrink the aneurysm over time.
Abdominal Aortic AneurysmAbdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder)Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)Finland - RecruitingPHASE3
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
This study looks at a new medicine, vicadrostat, for people with type 2 diabetes, high blood pressure, and heart disease. It aims to see if taking vicadrostat alongside empagliflozin can help reduce heart problems. Half the participants will get the study medicine, and half will get a dummy pill.
Diabetes Mellitus, Type 2HypertensionCardiovascular DiseasesFinland - Active not recruitingPHASE3
Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)
This study looks at a new drug, pembrolizumab, combined with standard chemotherapy after surgery for certain types of womb cancer (endometrial cancer). We want to see if this combination helps stop the cancer from coming back and helps people live longer compared to chemotherapy alone.
Endometrial NeoplasmsFinland - RecruitingPHASE3
A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus
This study is looking at a new medicine called nipocalimab for adults with moderate to severe lupus. It compares nipocalimab to a dummy treatment (placebo) to see if it can help reduce inflammation and improve lupus symptoms.
Lupus Erythematosus, SystemicFinland - Active not recruitingPHASE3
A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer
This study looks at a new drug called tucatinib for HER2-positive breast cancer that has spread. We want to see if adding tucatinib to standard treatments (trastuzumab and pertuzumab) helps more than a dummy pill (placebo). It also checks for side effects.
HER2 Positive Breast CancerFinland - Active not recruitingPHASE3
Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis
This study looks at the everyday safety and effectiveness of a new medicine, deucravacitinib, for people with psoriasis who have been in previous studies. It also checks how the body responds to common vaccines while taking this medicine.
PsoriasisFinland - RecruitingNA
HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial
This study looks at treating hip fractures quickly in older patients who also have heart problems. It compares fast surgery to usual care to see if it reduces deaths within 90 days, and also checks other important health outcomes.
Hip FracturesMyocardial InjuryFinland - Active not recruitingPHASE3
Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis
This study is looking at a medicine called tofacitinib for children aged 2-17 with a bowel condition called ulcerative colitis. It aims to see how well it works, how safe it is, and how the body uses it, especially if other treatments haven't worked.
Ulcerative ColitisFinland - AuthorisedTherapeutic confirmatory (Phase III)
LIBRETTO: Stimulan™ Local Antibiotic Delivery System Versus 4-Week Systemic Antibiotic Therapy for Diabetic Foot Osteomyelitis – A Prospective, Randomized, Controlled Trial
This study is looking at better ways to treat a serious foot infection called diabetic foot osteomyelitis. It compares a new local antibiotic treatment system with standard antibiotic pills or injections to see which is more effective at healing the infection and preventing its return.
Diabetic Foot OsteomyelitisFinland - AuthorisedTherapeutic exploratory (Phase II)
Randomized, Double-Blinded, Vehicle-Controlled, Parallel Group, Adaptive Proof-of-concept, Dose-selecting Phase 2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Intranasal Cenegermin (recombinant human Nerve Growth Factor [rhNGF]) in Adult Participants with subacute moderate to severe Traumatic Brain Injury (TBI).
This study is testing a new nasal spray called Cenegermin for adults who have recently had a moderate to severe head injury. We want to see if it's safe and how well people tolerate it, looking for any side effects over six months.
Subacute Moderate to Severe Traumatic Brain Injury (TBI)Finland - AuthorisedTherapeutic use (Phase IV)
CoCo-PCOS - Comprehensive Health Effects of Combined Contraceptives: a 6-month randomized, controlled, open-label trial of E4+DRSP, EE20µg+DRSP, and DRSP-only in women with PCOS
This study looks at how different birth control pills affect women with Polycystic Ovary Syndrome (PCOS) over six months. We want to see how these common medications impact their overall health and symptoms.
ContraceptionFinland - AuthorisedTherapeutic exploratory (Phase II)
FINACCESS - Finnish National Study for Early Access to Cancer Therapies
The FINACCESS study is looking at how well new cancer medicines work and if they cause side effects. It's for adult patients with different types of cancer. Doctors want to find out more about early access treatments.
CancerFinland - AuthorisedTherapeutic confirmatory (Phase III)
A double-blinded extension study to evaluate the long-term safety and tolerability of itepekimab in adult participants with inadequately controlled chronic rhinosinusitis with nasal polyps (CRSwNP) who participated in either EFC18418 or EFC18419 clinical studies
This study is looking at the long-term safety of a new medicine, itepekimab, for adults with nose polyps and ongoing sinus problems. It's for people who were in earlier trials and helps us understand if the treatment is safe over time.
Chronic rhinosinusitis with nasal polypsFinland - RecruitingPHASE2
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
This study looks at new medications for adults with moderate to severe Crohn's disease. Researchers want to see how well these 'targeted therapies' work and if they cause side effects, to find better ways to manage the condition.
Crohn's DiseaseFinland - Active not recruitingPHASE3
A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.
This study looks at the everyday safety and how well a drug called tolebrutinib is tolerated over a long time. It's for adults with different types of multiple sclerosis (MS) who have already been in earlier tolebrutinib studies.
Relapsing Multiple SclerosisSecondary Progressive Multiple SclerosisProgressive Relapsing Multiple SclerosisFinland - AuthorisedTherapeutic confirmatory (Phase III)
DAREON®-Lung-1: A Phase III multi-center, open-label, randomised trial of intravenous obrixtamig in combination with atezolizumab, carboplatin, and etoposide vs. atezolizumab, carboplatin, and etoposide as first-line treatment in patients with extensive-stage small cell lung cancer.
This study looks at a new drug, obrixtamig, alongside usual treatment for extensive small cell lung cancer. It aims to see if this new combination helps people live longer and feel better compared to the usual treatment alone.
small cell lung cancerFinland - RecruitingPHASE3
Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)
This study looks at a new drug called venetoclax for children, teenagers, and young adults with acute myeloid leukaemia (AML) that has come back. It aims to see if adding venetoclax to standard chemotherapy can help improve their chances of survival.
Acute Myeloid LeukemiaFinland - AuthorisedTherapeutic confirmatory (Phase III)
ROSETTA Lung-202: A Randomized, Double-Blind, Phase 3 Study of Pumitamig Monotherapy Compared to Pembrolizumab as First-line Treatment in Participants with Locally Advanced or Metastatic Non-Small Cell Lung Cancer with PD-L1 ≥ 50%
This study is comparing a new medicine called Pumitamig with a standard treatment, Pembrolizumab, for a type of lung cancer. Researchers want to see if Pumitamig can stop cancer from growing for longer or help people live longer than current treatment.
Non-Small Cell Lung CancerFinland - AuthorisedHuman Pharmacology (Phase I)- Other
A study to learn more about how safe BAY 3771249 is and how well it works in people with advanced or metastatic colorectal cancer that has a KRAS G12D mutation
This study is looking at a new medicine called BAY 3771249 for people with advanced bowel cancer. It's for those whose cancer has a specific change called a KRAS G12D mutation. The main aim is to see if the medicine is safe and if it helps to treat the cancer.
adenocarcinoma of the colon or rectumFinland - RecruitingPHASE3
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)
This study investigates if a drug called baricitinib can protect the body's insulin-making cells in children and adults newly diagnosed with type 1 diabetes. It aims to see if preserving these cells helps manage the condition better.
Diabetes Mellitus, Type 1Finland - Active not recruitingPHASE2
A Phase 2a/b Study of the Efficacy and Safety of Subcutaneous Amlitelimab in Adults With Nonresponsive Celiac Disease
This study is testing a new medicine, amlitelimab, for adults with coeliac disease that isn't getting better with a gluten-free diet. It looks at how well the medicine works and if it's safe, by checking changes in the gut and how people feel.
Coeliac DiseaseCeliac DiseaseFinland - RecruitingPHASE3
A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)
This study compares a new treatment called BMS-986393 with standard medicines for adults with multiple myeloma that has come back or not responded to previous treatment, including lenalidomide. We want to see if the new medicine works better and is safe.
Relapsed or Refractory Multiple Myeloma (RRMM)Finland - Recruiting
Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression
This study uses AI to predict heart and blood vessel problems like aneurysms and blockages. Researchers are looking at existing patient information to develop computer programs that can spot who might be at higher risk or whose condition might worsen.
Aneurysm AbdominalPeripheral Arterial DiseaseFinland - Active not recruitingPHASE3
A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma
This study is looking at three new medicines for advanced melanoma, a type of skin cancer. It aims to see if combining these medicines helps people with melanoma that has spread and has a specific gene change called 'BRAF'.
MelanomaFinland - Recruiting
The European NAFLD Registry
This study aims to understand fatty liver disease (NAFLD) better. Researchers collect information and samples from patients across Europe to find new ways to detect and monitor the disease, especially how it progresses from fatty liver to more serious conditions like fibrosis.
NAFLDNASHNASH - Nonalcoholic SteatohepatitisFibrosis, LiverFinland - RecruitingPHASE2, PHASE3
A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease
This study looks at a new treatment called belimumab for adults with a lung condition linked to scleroderma. Researchers want to see if it improves lung function and other symptoms, like skin thickening, compared to a dummy treatment.
Systemic Sclerosis Associated Interstitial Lung DiseaseScleroderma, SystemicFinland - RecruitingPHASE3
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
This study is testing a new medicine, XEN1101, for people with focal-onset seizures to see if it helps reduce seizures and is safe. Some people will get the real medicine, and others a dummy pill. It's for adults (18+) who already take seizure medicine.
Focal Onset SeizuresFinland