Skin conditions research
Psoriasis, eczema, acne, vitiligo and dermatology research.
264 indexed studies · 66 currently recruiting
Top conditions in this hub
- Atopic Dermatitis61
- Hidradenitis suppurativa32
- Plaque Psoriasis31
- Psoriasis20
- Dermatitis, Atopic18
- Moderate to Severe Plaque Psoriasis11
- Eczema9
- Hidradenitis Suppurativa (HS)8
- Moderate-to-severe atopic dermatitis7
- Atopic Dermatitis (Eczema)6
- Vitiligo6
- Psoriatic Arthritis5
- Atopic dermatitis (AD)5
- Breast Cancer4
- Radiation Dermatitis4
- Acne4
Recent studies
- Active not recruitingPHASE3
A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
This study is testing a new medicine called lutikizumab for people aged 12 and over with moderate to severe hidradenitis suppurativa (HS). It compares the new medicine to a dummy treatment (placebo) to see if it helps reduce HS symptoms and is safe.
United States · Argentina · Australia - Ongoing, recruitingTherapeutic exploratory (Phase II)
A phase 2B, multicenter, randomized, double-blind, placebo-controlled, dose-finding, efficacy and safety study of HRO350 in subjects with mild-to-moderate psoriasis (the ‘HeROPA’ study)
This study is testing a new treatment called HRO350 for people with mild to moderate psoriasis. Researchers want to see if it improves psoriasis symptoms and is safe to use. Some people will get HRO350, others will get a dummy treatment, to compare results over 26 weeks. It's for adults aged 18 and over.
Finland · Germany · Norway - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Randomized, 24-week, Placebo-controlled, Double-blind Study to Assess the Efficacy, Safety and Tolerability of Rocatinlimab (AMG 451) Monotherapy in Adult Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)
This study is looking at a new medicine called Rocatinlimab for adults with moderate to severe eczema. We want to see if it helps improve skin, reduce itching, and is safe over 24 weeks compared to a dummy medicine.
Poland · Estonia · Denmark - Ongoing, recruitingTherapeutic exploratory (Phase II)
A multicentre, randomised, double-blind, placebo-controlled, 12-week parallel-group trial to evaluate the efficacy and safety of oral BP1.7881 in adult patients with moderate-to-severe atopic dermatitis
This study is testing a new tablet called BP1.7881 for moderate to severe eczema in adults. We want to see if it helps improve skin symptoms and itching, compared to a dummy tablet, over 12 weeks.
Germany · Poland · France - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Multicenter, Randomized, Double-blind, Placebo- controlled, Parallel-group, Dose-ranging Study to Evaluate the Efficacy and Safety of DC-806 in Participants with Moderate to Severe Plaque Psoriasis
This study is looking at a new tablet treatment called DC-806 for people with moderate to severe plaque psoriasis. Doctors want to see how well it works to clear skin and if it's safe compared to a dummy pill.
Spain · Poland · Hungary - Ongoing, recruitingTherapeutic exploratory (Phase II)
A phase 2b, randomised, double-blind, placebo-controlled, multi-site, parallel-group, dose finding trial to evaluate the efficacy and safety of different doses of subcutaneously administered LEO 138559 in adult subjects with moderate-to-severe atopic dermatitis (AD)
This study is testing a new medicine, LEO 138559, for moderate to severe eczema in adults. We want to see if different doses are safe and if they help improve eczema symptoms over 16 weeks compared to a dummy medicine.
Romania · Germany · France - RecruitingPHASE3
A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis
This study looks at a new drug called Tralokinumab for children and babies with moderate to severe eczema. We want to see if it's safe and helps when given with standard eczema creams. It could offer new hope for managing this condition.
United States · Belgium · Canada - RecruitingPHASE3
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
This study compares a new medicine, deucravacitinib, with an existing one, ustekinumab, for long-term safety in people with moderate to severe plaque psoriasis. It focuses on participants who also have heart disease risk factors.
United States · Argentina · Australia - Active not recruitingPHASE3
A Study to Assess Efficacy and Safety of JNJ-77242113 Compared to Placebo and Ustekinumab in Participants With Moderate to Severe Plaque Psoriasis
This study is looking at a new medication, JNJ-77242113, for people with moderate to severe plaque psoriasis. It compares the new medication to a widely used treatment (ustekinumab) and a dummy medicine (placebo) to see how safe and effective it is.
United States · Argentina · Australia - Active not recruitingPHASE3
Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis
This study looks at the everyday safety and effectiveness of a new medicine, deucravacitinib, for people with psoriasis who have been in previous studies. It also checks how the body responds to common vaccines while taking this medicine.
United States · Australia · Canada - Active not recruitingPHASE2
Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis
This study looks at a new psoriasis medicine called envudeucitinib. It's for people who have already taken part in an earlier study of this medicine. We want to see how safe and helpful it is over a longer time for widespread plaque psoriasis.
United States · Canada - RecruitingPHASE2
A Study of Zasocitinib in Adults With Hidradenitis Suppurativa
This study is looking at a new medicine called Zasocitinib for adults with Hidradenitis Suppurativa (HS). Researchers want to see if it's safe, how well it works, and if people can tolerate it. HS causes painful bumps, usually where skin rubs together.
United States · Australia · Canada - RecruitingPHASE2
Dose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque Psoriasis
This study is testing a new medicine, ORKA-001, for people with moderate to severe plaque psoriasis. It aims to find the best dose and see how well it works and if it's safe compared to a dummy treatment.
United States · Canada · Germany - RecruitingPHASE2
A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis
This study is testing a new medicine called IMG-007 for adults with moderate to severe eczema. Researchers want to see if it's safe and helps improve symptoms like itchy skin, compared to a dummy medicine.
United States · Canada - Active not recruitingNA
Randomized Phase III Trial With Mepitel Film for the Prophylaxis of Radiation Dermatitis in Breast Cancer Patients
This study looks into using Mepitel Film to help prevent skin reactions during radiotherapy for breast cancer. It compares the film to standard skin care to see if it reduces problems like redness and soreness, especially for certain patients.
Canada - Active not recruitingNA
Efficacy Study With StrataXRT for the Prophylaxis of Radiation Dermatitis in Adjuvant Breast Radiation Treatment in Large Breasted Women Using a Prone Technique
This study looks at how a special gel called StrataXRT can help prevent skin problems (like redness and soreness) for women with larger breasts having breast cancer radiotherapy. It aims to see if the gel can reduce these side effects even when women are treated lying on their front.
Canada - RecruitingPHASE3
Topical Betamethasone Versus Moisturizer in Preventing Radiation Dermatitis in Large-Breasted Patients Treated in the Prone Position
This study looks at whether a cream called betamethasone can reduce skin irritation (dermatitis) caused by radiation treatment for breast cancer. It focuses on women with larger breasts who are treated lying face down (prone position).
Canada - Active not recruitingPHASE2
A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis
This study is testing a new medicine called Afimkibart for moderate to severe eczema in adults. Researchers want to see if it's safe and effective compared to a dummy treatment. It's a Phase 2 trial, meaning it's still early stage research.
United States · Brazil · Canada - AuthorisedTherapeutic exploratory (Phase II)
C6231002 - A PHASE 2B, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE RANGING STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF 08049820 IN ADULT PARTICIPANTS WITH MODERATE TO SEVERE ATOPIC DERMATITIS
This study is looking into a new medication for adults with moderate to severe eczema. It wants to see how well it works and if it's safe. Some people will get the new medicine, and others will get a dummy medicine to compare the effects.
Poland · Czechia · Germany - Ongoing, recruitingHuman Pharmacology (Phase I)- Other
A multicenter, Phase 1b, double-blind, placebo-controlled study to evaluate the safety and tolerability, and the efficacy of si-544 in adults with psoriasis vulgaris or psoriatic arthritis
This study is testing a new medicine, si-544, for adults with psoriasis or psoriatic arthritis. It's a first-step study to check if the medicine is safe and if it helps with these conditions. Some people will get the real medicine, others a dummy treatment.
Germany - RecruitingPHASE2
A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
This study looks at a new medicine called SAR445399 for adults with moderate to severe Hidradenitis Suppurativa (HS). It aims to see if the medicine is safe and effective compared to a dummy treatment, and to find the best dose.
United States · Argentina · Australia - Active not recruitingPHASE3
ELAPR002f Injectable Gel in the Treatment of Atrophic Acne Scars
This study looks into a new injectable gel, ELAPR002f, for treating indented acne scars. It aims to see if the gel is safe and works well to fill in these scars. Adults with moderate to severe acne scars on their cheeks can take part.
Canada · Germany - Active not recruiting
A Study to Evaluate the Safety of Remsima® SC in the Treatment of RA, AS, PsA and Ps
This study looks at how safe a medicine called Remsima® SC is for people with certain long-term conditions like rheumatoid arthritis, a type of spinal arthritis, psoriatic arthritis, and psoriasis. It aims to see if there are any unwelcome side effects.
France - Ongoing, recruitingTherapeutic exploratory (Phase II)
Phase 2, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy and Safety of AVTX-009 in Patients with Moderate to Severe Hidradenitis Suppurativa (LOTUS)
This study is testing a new medicine called AVTX-009 for a skin condition called hidradenitis suppurativa (HS). We want to see if it helps reduce painful lumps and spots, and if it's safe to use. Half the people will get the new medicine and half will get a dummy medicine.
France · Italy · Bulgaria - Recruiting
Defects of Keratinocytes Function in Dermatologic Patients
This study looks at a skin condition called hidradenitis suppurativa (HS). Researchers want to understand how tiny skin cells called keratinocytes work when someone has HS. They hope this will lead to better treatments for HS, an often painful and challenging long-term condition.
Austria · Belgium · France - Recruiting
Real-world Effectiveness Study of Long-term Treatment With Dupilumab in Participants ≥6 Years With Atopic Dermatitis
This study looks at how Dupilumab works for people aged 6 and over with eczema in their daily lives. It aims to understand how the treatment affects their symptoms, quality of life, and overall control of their eczema over two years.
Germany - Active not recruitingPHASE3
A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis
This study looks at a new combination treatment for teenagers and adults with moderate to severe eczema. It combines a new tablet called upadacitinib with steroid creams to see how well it works and if it's safe.
United States · Australia · Austria - RecruitingPHASE3
A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older With Moderate to Severe Eczema
This study looks at a medicine called abrocitinib for children aged 2 and older with moderate to severe eczema. It checks how safe and effective it is over the long term, with some children having used it before and others trying it for the first time.
United States · China · Germany - Active not recruitingPHASE3
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis
This study is looking at a new medicine called nemolizumab for people with moderate to severe eczema. It aims to understand how safe and effective the medicine is over a long period. Participants would have been in a previous nemolizumab study.
United States · Australia · Austria - Active not recruitingPHASE3
A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy
This study looks at a new drug, upadacitinib, for moderate to severe Hidradenitis Suppurativa (HS). It's for adults and teenagers whose HS hasn't improved with other treatments. We'll check if it's safe and helps reduce HS symptoms.
United States · Argentina · Australia - RecruitingNA
Assessment of the Effect of a Dermatology-Oriented Spa Therapy on the Quality of Life of Patients With Psoriasis
This study looks at how a special skin spa treatment might improve the lives of people in the UK with psoriasis. It checks if their quality of life gets better after a 3-week stay at a dermatology-focused spa, over several months.
France - RecruitingPHASE2
Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis
This study is looking into new ways to treat moderate to severe atopic dermatitis (eczema). It will test a new medicine called GHZ339 to see if it's safe and effective for adults. We want to find better options for people living with this skin condition.
United States · Argentina · Canada - Active not recruitingPHASE3
Effectiveness and Safety of Lebrikizumab Treatment in Adults and Adolescents With Moderate-to-Severe Atopic Dermatitis
This study looks at how well a new medicine, lebrikizumab, works and if it's safe for teenagers and adults with moderate to severe eczema. It wants to see if the medicine can improve skin symptoms over 24 weeks.
Germany · Netherlands · United Kingdom - RecruitingPHASE2
A Dose-ranging Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Galvokimig in Adult Study Participants With Atopic Dermatitis
This study is testing a new medicine, Galvokimig, for adults with moderate to severe eczema (atopic dermatitis). We want to find the best dose and check how well it works and if it's safe compared to a dummy drug.
United States · Bulgaria · Canada - Active not recruiting
Tilrdakizumab Almirall
This study is looking at how a medicine called tildrakizumab works in people with moderate to severe psoriasis. Researchers are studying skin samples to understand how this treatment helps improve psoriasis and how its effects last over time.
Germany - Recruiting
International Rare And Severe Psoriasis Expert Network
This study looks at a skin condition called Pustular Psoriasis over five years. We want to understand how it changes and how different treatments work. By collecting information from many people, we hope to improve understanding and care for this condition.
Germany · Italy · Portugal - Recruiting
PsoBest - The German Psoriasis Registry
PsoBest is a long-running study in Germany looking at how well different medicines work for psoriasis and psoriatic arthritis in real life. It aims to understand the long-term effects, safety, and best ways to use these treatments for patients.
Germany - Not yet recruiting
Characterization of the Fungal Immunopeptidome Involved in the Immunopathological Mechanisms of Psoriasis
This study looks into how common fungi on our skin and in our gut might be linked to psoriasis. Researchers want to understand if these fungi trigger the immune system, causing the skin problems seen in people with psoriasis, hoping this will lead to new treatments.
France - Recruiting
Creation of a Monocentric Cohort of Patients Treated for Acne at the Nantes University Hospital
This study at Nantes University Hospital is looking at people with acne. It aims to understand the condition better, see what treatments work best, and explore how acne affects daily life and mental well-being. It's the first study of its kind in France.
France - Active not recruitingPHASE3
A Study to Test the Long-term Treatment of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa
This study looks at the long-term safety of a treatment called bimekizumab for people with moderate to severe hidradenitis suppurativa (HS). It builds on earlier studies to see how well the treatment works and if it's safe over a longer period.
United States · Australia · Belgium