Women's health research
Pregnancy, menopause, endometriosis, PCOS and other women's health studies.
408 indexed studies · 222 currently recruiting
Top conditions in this hub
Recent studies
- Active not recruiting
Gestational Diabetes Monitoring and Management
This study looks at information from pregnant women with gestational diabetes to predict potential problems for mum and baby, and to work out the best way to monitor blood sugar. It uses existing data to help improve care and reduce the number of blood tests needed.
United Kingdom - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A randomized controlled trial comparing sequential of two shots of CFA vs CFA + rFSH for Elective Fertility Preservation. The 2-shot protocol.
This study looks at a new way to help women preserve their fertility. Researchers are comparing two different methods for stimulating the ovaries to collect eggs, using a combination of hormone medications. The goal is to find the best way to collect healthy eggs for future use.
Spain - RecruitingPHASE3
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
This study looks at how best to treat a type of cancer called germ cell tumours in children and adults. It compares simply watching the tumour after surgery with different chemotherapy treatments to see which works best and causes fewer side effects.
United States · Australia · Canada - RecruitingNA
Whole-Body Cryotherapy as a Non-Pharmacological Treatment to Reduce Chronic Pelvic Pain and Improve Quality of Life in People With Endometriosis
This study looks at whether whole-body cryotherapy, which is brief exposure to very cold temperatures, can help people with endometriosis reduce their pain and improve their quality of life. It’s testing if this non-drug treatment safely manages symptoms.
United Kingdom - Recruiting
Early Versus Late Monitoring Among Pregnant Women With a History of Gestational Diabetes
This study looks at pregnant women who had gestational diabetes before. We want to see if checking blood sugar early in pregnancy leads to better health for mum and baby, compared to a later check-up. The goal is to improve care for mums with this history.
United Kingdom - Active not recruitingPHASE3
Olaparib Treatment in BRCA Mutated Ovarian Cancer Patients After Complete or Partial Response to Platinum Chemotherapy
This study looks at a drug called Olaparib for women with a specific type of ovarian cancer. It's for those whose cancer has improved after chemotherapy and have a change in their BRCA gene. We want to see if Olaparib helps keep the cancer away longer.
United States · Australia · Belgium - Active not recruitingPHASE2
A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors
This study looks at a new treatment called trastuzumab deruxtecan (T-DXd) for several types of advanced cancer where a protein called HER2 is present. Researchers want to see how well it works and if it's safe for people with bladder, pancreatic, and other solid tumours.
United States · Australia · Belgium - Recruiting
PRospective Evaluation of Peripartum Anticoagulation ManaGement for ThrOmboembolism
This study looks at how blood thinners are used for pregnant people at risk of blood clots. It aims to understand the best ways to manage these medications during and after childbirth to keep mothers safe and healthy.
United States · Canada · Denmark - Not yet recruitingPHASE2
A Probiotic Based Intervention in Pregnancies Complicated by GDM
This study looks at whether a special probiotic and prebiotic supplement can help pregnant people with gestational diabetes manage their blood sugar and improve their gut health. It's hoped this might be a new way to help mothers and babies.
Canada - RecruitingPHASE3
Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial
This study compares keyhole surgery (minimally invasive surgery) with traditional open surgery (laparotomy) for advanced ovarian cancer. It's for women who've already had chemotherapy. The aim is to see if keyhole surgery is as good or better for recovery and quality of life.
United States · Canada · Italy - Active not recruitingNA
The CanDo (Canadian Donor Milk) Trial
This study looks at whether giving donor breast milk or formula to certain babies in hospital helps them with breastfeeding and their health. It focuses on babies who might need extra milk, like those born to diabetic mothers, or who are smaller or a little early.
Canada - RecruitingPHASE2
Menopur And Rekovelle Combination Study Version 2.0
This study looks at a new way to give fertility medicines (REKOVELLE and MENOPUR) for IVF. We're checking if dosing based on a woman's age and weight works as well as current methods for helping women get pregnant.
Canada - Active not recruitingPHASE1, PHASE2
Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer
This study is testing a new cell therapy called gavo-cel for advanced cancers like mesothelioma and ovarian cancer. It explores how well gavo-cel works, both alone and with other cancer drugs, in people whose tumours produce a specific protein called mesothelin.
United States · Canada - RecruitingPHASE1
A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors
This study is testing a new drug, CTIM-76, for some difficult-to-treat cancers like ovarian, testicular, and endometrial cancer. It's an early-stage study to check for safety and find the right dose. The drug works by helping your immune system fight the cancer.
United States · United Kingdom - Recruiting
13C-Glucose Tracing of Tumour and T Cells in the Ascites of Ovarian Cancer Patients.
This study looks at how cells in ovarian cancer ascites (fluid build-up) use energy. Researchers will give a special, safe form of sugar ([U-13C]glucose) to patients undergoing fluid drainage. This helps them understand cancer and immune cell activity to find better ways to treat this condition.
Canada - RecruitingNA
Exogenous Ketone Supplementation in Females with Polycystic Ovary Syndrome
This study looks into whether a ketone supplement can help women with Polycystic Ovary Syndrome (PCOS). We want to see if it improves heart health factors like blood sugar, blood pressure, and how blood vessels work. The supplement might offer a new way to manage some PCOS effects.
Canada - AuthorisedTherapeutic exploratory (Phase II)
The NOVA-NOA Trial A Novel Aromatase Inhibitor, Leflutrozole, for Treatment of Non-Obstructive Azoospermia
This study, called NOVA-NOA, is looking into a new medicine called Leflutrozole to treat male infertility when sperm aren't found in a man's ejaculate. We want to see if this medicine can help men produce sperm in their semen.
Denmark - Recruiting
Selective Fetal Growth Restriction in Monochorionic Twins - an International Investigation
This study looks into why some identical twins (monochorionic) grow differently in the womb, a condition called selective fetal growth restriction (sFGR). We want to improve how doctors diagnose it, predict problems, and understand its effects on babies and parents.
United States · Belgium · Canada - RecruitingNA
Evaluating the Feasibility of elleFA App Implementation
This study is testing a new smartphone app called elleFA, made for women with endometriosis. It aims to see if the app helps women track their symptoms and communicate better with their doctors. We want to find out how easy it is to use the app and if it improves patients' experiences.
Canada - Recruiting
Pregnancy Surveillance Program of Patients Exposed to Epidiolex/Epidyolex During Pregnancy
This study looks at the health of pregnant women and their babies if the mother took Epidiolex (a medicine for certain types of seizures) during pregnancy. Researchers will follow mothers and babies for up to a year after birth to see how they are doing.
United States · Germany - AuthorisedTherapeutic exploratory (Phase II)
A Phase 2 Study of [68Ga]BED003 for PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications
This study looks at a new type of body scan called a [68Ga]BED003 PET scan. It aims to see how well this scan can find certain cancers like bowel, stomach, and ovarian cancer by looking for a specific protein, helping doctors see where the cancer might be.
Netherlands · Italy - RecruitingPHASE3
A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine
This study is looking into a new medication called rimegepant. It's for women who get migraines around their period. We want to see if this medicine can help prevent these 'menstrual migraines' and if it's safe to use.
United States · Argentina · Canada - AuthorisedTherapeutic exploratory (Phase II)
A Phase II, Multicenter, Open-Label Trial of DB-1311 in combination with BNT327 or DB-1305 in Participants with Advanced/Metastatic Solid Tumors
This study is testing new combinations of medicines (DB-1311 with BNT327 or DB-1305) for people with several types of advanced cancer. It aims to see how safe the treatments are and if they can shrink tumours, helping us find better ways to fight cancer.
Italy · Poland · France - Not yet recruiting
Prevalence of Carriage of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacteria in Preterm Premature Rupture of Membranes : A French Multicenter Cohort Study
This study looks at how common antibiotic-resistant bugs are in pregnant women whose waters break early. We want to understand these germs better to help doctors choose the best treatments for mums and babies, protecting them from infection.
France - RecruitingNA
Evolution of Sexual Life Quality of Women With POI Before and After Introduction of Hormone Replacement Therapy
This study looks at how hormone replacement therapy (HRT) affects the sex life of women with premature ovarian insufficiency (POI). It aims to see if HRT improves sexual satisfaction and helps women feel better overall, using surveys to track changes before and after starting treatment.
France - Recruiting
Effects of Oncological Treatment During Pregnancy on Mother and Child
This study looks at how cancer and its treatments during pregnancy affect mums and their babies. Researchers want to see if babies exposed to treatments like chemotherapy develop normally, and they'll also track the mothers' health.
United States · Argentina · Austria - RecruitingNA
Life vs. Digital Music Interventions Performed by Professionals Throughout Pregnancy to Increase Mental Health for Mothers and Their Offspring
This study looks at how live music and creative activities like singing and dancing might improve mental health for pregnant women and their babies. They're comparing these activities in person with digital versions to see which works best.
Germany - RecruitingNA
Ablative Technique For Ovarian Preservation In Endometrioma
This study looks at different surgeries for ovarian cysts caused by endometriosis. It aims to find out which surgery helps women get pregnant, how often cysts return, and what side effects occur. It's for women aged 18-43 with endometriosis and ovarian cysts.
France - Recruiting
Pregnancy and Inflammatory Bowel Disease
This study looks at how inflammatory bowel disease (IBD) affects pregnancy and how pregnancy affects IBD. We're studying women with Crohn's disease or ulcerative colitis who have been pregnant, aiming to understand symptoms during pregnancy and after birth.
France - Active not recruitingNA
Investigation of Tumour Spectrum of Germline Mutations in Breast and Ovarian Cancer Genes.
This study looks at new genes linked to breast and ovarian cancer. If you're having BRCA gene testing, you might be asked to join. We're learning how these genetic changes affect cancer risk in families, helping us understand and manage cancer better.
France - Recruiting
Predicting the Pain Outcome of Surgery for Endometriosis
This study looks at whether surgery helps with pain in severe endometriosis. We're using brain scans to see who might benefit most. This helps us understand if surgery is the best option for pain relief for some women.
United Kingdom - RecruitingNA
Exploration of Allograft Humoral Rejection in Chronic Histiocytic Intervillositis
This study looks into a rare pregnancy condition called Chronic Histiocytic Intervillositis (CHI). It affects about 5 in 10,000 pregnancies and can cause serious issues like babies not growing well, stillbirths, and miscarriages. We want to understand what causes it to find better ways to help mothers.
France - RecruitingNA
Argon Plasma Treatment for Ovarian Endometrioma Compared to Standard Cystectomy
This study compares two ways to treat ovarian endometriomas (cysts from endometriosis) to see how they affect a woman's egg count. We're looking at a standard surgery versus a newer argon plasma treatment. It's for women aged 18-40 in Germany.
Germany - Recruiting
The Impact of Hormonal Contraceptive Use and Lifestyle Factors on Fracture Risk and Bone Quality in Young Female Adults
This study looks at how birth control and lifestyle affect bone health in young women in the German armed forces. Researchers want to understand if different contraceptives, exercise, diet, and other factors impact bone strength and reduce the risk of breaks.
Germany - Recruiting
Mechanisms and Factors Responsible for the Inhibition of Transposons During Fetal Gonad Development in Humans
This study looks at how tiny moving gene segments, called 'transposons', are controlled in a baby boy's developing reproductive organs. Researchers are studying tissue from unborn babies after a termination of pregnancy to understand these important processes.
France - Recruiting
Institut Paoli Calmettes Ovarian Cancer Database
This study is gathering information from patients at Institut Paoli-Calmettes who have been diagnosed with ovarian cancer. Researchers want to better understand ovarian cancer by collecting health details and treatment paths from these patients.
France - RecruitingNA
A Nutrition and Exercise Lifestyle Intervention Program Participant Choice Approach
This study looks at how giving pregnant people a choice in their diet and exercise plan affects their commitment to it. It aims to see if having a say in when they start different parts of the plan helps them stick with it and manage healthy weight gain during pregnancy.
Canada - Not yet recruiting
EMBRACE- BLOOM - Building Literacy and Outcomes Through Observation and Monitoring: Information Needs and Wearable Data in Pregnancy Couples
This study looks at how pregnant women and their partners find and use health information. We want to understand what information they need, where they look for it, and what makes it easy or hard to get trusted advice from early pregnancy until after the baby is born.
United Kingdom - RecruitingNA
Cryopreservation of Prepubertal Testicular Tissue for Preservation of Fertility in Young Boys With Cancer
This study aims to help young boys with cancer preserve their future ability to have children. Because cancer treatments can cause infertility, doctors will freeze a small piece of testicular tissue from these boys. This tissue might be used later to restore their fertility.
United Kingdom - Active not recruitingNA
Efficacy of Internet-based Cognitive Behavioral Therapy for Endometriosis
This study is looking at a type of online talking therapy called Cognitive Behavioural Therapy (CBT) to help people manage the challenges of endometriosis. It aims to see if this online approach can reduce the difficulties caused by the condition.
Germany