Latest studies
- Recruiting
Care of people at the end of their lives in the rural and coastal communities of the South West Peninsula of England
This study aims to improve end-of-life care in rural and coastal areas of Devon, Cornwall, and Somerset. It involves talking to patients, families, and professionals to understand current care and find ways to make it better for everyone involved.
People at the end of life, family members and professionalsScotland - RecruitingNot Applicable
Vagus nerve stimulation for epilepsy in children and adults: assessment of longer term clinical and cost effectiveness in a randomised controlled trial
This study looks at how well a treatment called Vagus Nerve Stimulation (VNS) works for children and adults with epilepsy that hasn't responded to other medicines. We want to understand its long-term benefits and if it helps people with learning difficulties.
EpilepsyScotland - Recruiting
Understanding visual processing differences using short video tasks in adults with cerebral visual impairment
This study looks at how adults with a vision condition called Cerebral Visual Impairment (CVI) see and understand short everyday videos. We want to compare this to people with typical vision to better understand CVI and find ways to help in the future.
Cerebral visual impairment (CVI)Scotland - Recruiting
A UK study of minimally invasive emergency treatment of sudden bleeding from the lower bowel
This study looks back at records of patients in the UK and other countries who had a special X-ray guided procedure called embolisation to stop sudden bleeding from their bowel. It aims to understand how well this treatment works and to improve care for similar cases in the future.
Patients who have undergone angiography +/- embolisation for acute non-variceal lower GI haemorrhage.Scotland - Recruiting
Evaluating the role of IL-17 as an orchestrator of peripheral-central cross talk in depressive symptoms
This study looks at how a medicine blocking IL-17, used for skin and joint conditions, might help improve depression in people with these conditions. It uses brain scans to see if reducing inflammation in the body also affects the brain and mood.
Depressive symptoms in people with active psoriatic disease and how IL-17 inhibition affects inflammation in brain and immune processes.Scotland - Not yet recruitingNot Applicable
Project COMFORT Study- Understanding how new blood sampling devices for use at home compare with standard hospital vein blood tests
The Project COMFORT Study is looking at new ways to collect blood samples at home for people with, or at risk of, heart conditions. We want to see if these new methods work as well as traditional hospital blood tests and how easy they are for patients to use.
Cardiovascular disease (CVD) or elevated cardiovascular riskScotland - Recruiting
Phase I clinical trial to determine maximum tolerable dose of African Bitter Root Food Supplement
This study looks at a traditional herbal remedy called African Bitter Root Supplement (ABRS). We want to find the highest amount that healthy people can take safely. This information will help us plan future studies on whether ABRS can help with conditions like sickle cell disease or osteoarthritis.
Dose escalation in healthy volunteers for subsequent Phase II trial of use in sickle cell disease and osteoarthritisScotland - Recruiting
Protein engineering to design better enzyme replacement therapies for Fabry disease
Researchers are developing new treatments for Fabry disease using AI. This study aims to test these new enzymes in blood and urine samples to see if they cause fewer immune reactions than current treatments. It’s for people with Fabry disease over 16.
Fabry diseaseScotland - Recruiting
DRAGON: Are reusable surgical drapes and gowns as good as disposable surgical drapes and gowns at increasing days alive and at home after surgery?
This study compares reusable and disposable surgical drapes and gowns to see if reusable options are just as safe and effective, aiming to make operations more environmentally friendly. It's part of a bigger effort to reduce the NHS's carbon footprint.
Patients (adults) undergoing elective or emergency surgery with at least one incision ≥5 cm in adults and a clean-contaminated, contaminated or dirty wound, in NHS hospitals where there is equipoise to use either disposable or reusable drapes and gowns.Scotland - Not yet recruiting
Understanding the role of neutrophil enzymes in a type of asthma with low inflammation
This study is looking into a difficult-to-treat type of asthma called Type 2-low asthma. Researchers want to see if certain immune cells called neutrophils and their proteins are higher in people with this type of asthma. The goal is to find new ways to treat it and improve lives.
Type 2 inflammatory asthmaScotland - Recruiting
Can new imaging techniques help us to detect umbilical cord abnormalities in pregnancy?
This study looks at how the placenta and umbilical cord develop during pregnancy using special scans. Researchers want to see if these scans can help spot potential problems early and improve understanding of pregnancy health for mums and babies.
Placental dysfunctionScotland - Recruiting
Treatment preferences for irreversible pulpitis
This study looks at how best to help adults understand and choose treatments for a painful dental problem called irreversible pulpitis. It compares two tools, one with comics, to see which helps patients make better decisions about their care.
Management of severe or irreversible pulpitisScotland