Latest studies
- RecruitingPHASE3
A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs
This study is testing a new medicine, Debio 4126, for people with acromegaly, a hormone disorder, who are already taking similar treatments. We want to see if Debio 4126 can help keep their hormone levels stable compared to a dummy drug.
AcromegalySerbia - Active not recruitingPHASE3
Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia With Inhibitors
This study looks at a new medicine called concizumab for haemophilia A or B with inhibitors. It aims to see if it can prevent bleeding and is safe. Some people will get the new medicine straight away, others later, all through daily injections at home.
Haemophilia A With InhibitorsHaemophilia B With InhibitorsSerbia - RecruitingPHASE3
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation
This study looks at a new medicine called ziltivekimab for people with heart failure and inflammation. It aims to see if monthly injections of ziltivekimab can help, compared to a dummy medicine, over a few years.
Heart FailureSerbia - Recruiting
Fabry Disease Registry & Pregnancy Sub-registry
This study tracks the health of people with Fabry disease over time, including pregnant women. It helps doctors better understand the disease and improve care, without giving any new treatments. It's about observing, not experimenting.
Fabry DiseaseSerbia - RecruitingPHASE2, PHASE3
Phase 2/3 Study of KPL-387 in Recurrent Pericarditis
This study is testing a new medicine, KPL-387, for people with recurrent pericarditis, a condition causing chest pain and inflammation around the heart. We want to see if it's safe and helps reduce symptoms and prevent the problem from coming back.
PericarditisPericarditis AcuteRecurrent PericarditisSerbia - RecruitingPHASE2
Rademikibart Add-on Treatment of an Acute COPD Exacerbation (Seabreeze STAT COPD)
This study looks at a new medicine called rademikibart for severe flare-ups of COPD. It's for people whose COPD flare-ups are linked to a specific type of swelling (inflammation) in their body, aiming to see if it helps alongside usual treatments.
COPD Acute ExacerbationSerbia - Active not recruitingPHASE3
A Phase III Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Non Small Cell Lung Cancer (NSCLC) Whose Disease Progressed On or After Prior Anti PD (L)1 Therapy And Platinum Based Chemotherapy
This study looks at a new combination of drugs, ceralasertib and durvalumab, for people with advanced lung cancer that has grown after previous treatments. It compares this new combination to a standard chemotherapy drug, docetaxel, to see which works better and is safer.
Advanced or Metastatic Non-Small Cell Lung CancerSerbia - RecruitingPHASE3
Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML
This study is looking at a new drug, quizartinib, combined with standard chemotherapy for adults recently diagnosed with a specific type of leukaemia called AML. We want to see if this combination improves treatment outcomes compared to chemotherapy alone.
LeukemiaSerbia - RecruitingPHASE2
Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
This study is testing a new medicine, Imeroprubart, for adults with a nerve condition called Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). Researchers want to see if it's safe and helps improve symptoms compared to a dummy treatment.
Chronic Inflammatory Demyelinating PolyneuropathySerbia - RecruitingPHASE3
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
This study looks at a new medicine called zilebesiran for people with high blood pressure that isn't well controlled, especially if they also have heart problems or are at high risk of developing them. The aim is to see if zilebesiran can reduce serious heart-related events like heart attacks or strokes.
High Risk Cardiovascular DiseaseHypertensionHigh Cardiovascular RiskSerbia - Recruiting
SCAD : a Registry of Spontaneous Coronary Artery Dissection
This study is gathering information on a heart condition called Spontaneous Coronary Artery Dissection (SCAD). It's looking at how doctors currently diagnose and treat SCAD across Europe to learn more about it and improve care for patients.
Spontaneous Coronary Artery DissectionSerbia - Active not recruitingPHASE3
A Study Comparing Risankizumab to Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Have a History of Inadequate Response to or Intolerance to at Least One Disease Modifying Anti-Rheumatic Drug (DMARD) Therapy
This study compares a new medicine, risankizumab, with a dummy treatment (placebo) for people with active psoriatic arthritis. It checks how safe and effective risankizumab is, especially for those who haven't responded well to other treatments.
Psoriatic ArthritisSerbia - Active not recruitingPHASE3
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
This study is looking at a medicine called semaglutide for a liver condition called non-alcoholic steatohepatitis (NASH). Participants will receive either semaglutide or a dummy medicine. It's a long study, lasting about 5 years, with regular clinic visits.
Non-alcoholic SteatohepatitisSerbia - Active not recruitingNA
SyncAV Post-Market Trial
This study looks at a special heart device for people with heart failure. We're testing if a new setting, called SyncAV ON, helps the device work better and improve the heart's function more than the usual settings.
Congestive Heart FailureSerbia - Active not recruitingPHASE2, PHASE3
An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH)
This study looks at the long-term safety of a new inhaled medicine, Treprostinil Palmitil (TPIP), for people with a lung condition called Pulmonary Arterial Hypertension (PAH). It's for those who have already tried TPIP in earlier studies.
Pulmonary Arterial HypertensionSerbia - RecruitingPHASE3
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
This study is testing a new medication called Tulisokibart for people with moderate to severe Crohn's disease. Researchers want to see if it's safe and effective in reducing symptoms and improving the gut lining. It involves different ways of giving the medicine compared to a dummy treatment.
Crohn's DiseaseSerbia - Active not recruitingPHASE3
A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity
This study is looking into a new treatment called Dazodalibep for Sjögren's Syndrome. It wants to see if the treatment helps reduce symptoms and if it's safe for people whose Sjögren's is causing moderate to severe problems in their body.
Sjogren's SyndromeSerbia - Recruiting
Pompe Disease Registry Protocol
This registry tracks people with Pompe disease globally. It helps us understand the condition better, how it changes over time, and the effects of treatments. The goal is to improve care for everyone with Pompe disease.
Glycogen Storage Disease Type IIPompe DiseaseSerbia - Active not recruitingPHASE3
Treatment Combination of Durvalumab, Tremelimumab and Enfortumab Vedotin or Durvalumab and Enfortumab Vedotin in Patients With Muscle Invasive Bladder Cancer Ineligible to Cisplatin or Who Refuse Cisplatin
This study looks at new drug combinations for bladder cancer that has spread into the muscle. It compares them to standard treatment for people who can't take or don't want cisplatin chemotherapy before surgery to remove their bladder. The aim is to find more effective and safe options.
Muscle Invasive Bladder CancerSerbia - RecruitingPHASE3
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients
This study looks at two different drug treatments for advanced non-small cell lung cancer. It compares a new drug called ivonescimab with a standard treatment, pembrolizumab, both given with chemotherapy. The aim is to see which treatment works better and is safer.
Non-Small Cell Lung CancerSerbia - RecruitingPHASE1, PHASE2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
This study is testing a new medicine, LTP001, to see if it's safe and how it works in healthy people. Then, it will study people with a lung condition called Pulmonary Arterial Hypertension (PAH) to see if it helps them and if it's safe.
Healthy Volunteers, Pulmonary Arterial HypertensionSerbia - Active not recruitingPHASE3
Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors
This study looks at a new medicine called concizumab for people with haemophilia A or B without inhibitors. It aims to see how well it prevents bleeding and if it's safe. Participants will take the medicine daily, usually by injection under the skin, for up to 8 years.
Haemophilia A Without InhibitorsHaemophilia B Without InhibitorsSerbia - Active not recruitingPHASE2, PHASE3
A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis
This study is looking at a new medicine called guselkumab for people with ulcerative colitis that isn't well-controlled. We want to see if it helps reduce symptoms and if it's safe to use for those with moderate to severe forms of the condition.
Ulcerative ColitisSerbia - Active not recruitingPHASE3
A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease
This study is looking into the long-term effects and safety of a medicine called mirikizumab for people with Crohn's disease. Participants have already taken part in a related study, and this new study will help us understand how the medicine works over a longer period.
Crohn's DiseaseSerbia - Active not recruitingPHASE2, PHASE3
A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease
This study looks at a new medicine called guselkumab for adults with moderately to severely active Crohn's disease. Researchers want to see how well it works and if it's safe compared to other treatments or a dummy medicine.
Crohn's DiseaseSerbia - RecruitingPHASE3
An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia
This study looks at the long-term safety of a new medicine, KarXT, for people with schizophrenia whose current treatment isn't working well enough. It's for those who have already started in a previous related study.
SchizophreniaSerbia - Recruiting
POS-ARI-ER Observational Study of Acute Respiratory Infections
This study looks at how adults in European hospitals are diagnosed and treated for severe chest and breathing infections. It aims to understand different approaches and what causes these infections, including viruses like flu and coronaviruses, to improve care.
Acute Respiratory InfectionAcute Respiratory Tract InfectionSerbia - RecruitingPHASE3
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
This study looks at a new medicine, Baxdrostat, combined with an existing one, Dapagliflozin, for people with long-term kidney disease and high blood pressure. It aims to see if this combination can help protect the kidneys and heart better than Dapagliflozin alone.
Chronic Kidney Disease and HypertensionSerbia - Active not recruitingPHASE2
Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)
This study is testing new treatments for advanced bladder cancer. It compares a new drug, zelenectide pevedotin, alone and with pembrolizumab, against standard chemotherapy. We want to see how well these treatments work and if they are safe for people with bladder cancer that has spread.
Metastatic Urothelial CancerSerbia - RecruitingPHASE3
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
This study is testing a new medicine called Afimkibart for people with moderately to severely active Crohn's disease. It's a Phase 3 study, which means it's a big step before the medicine might become widely available, looking at how well it works and if it's safe.
Moderately to Severely Active Crohns DiseaseSerbia - Active not recruitingPHASE3
A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.
This study looks at the everyday safety and how well a drug called tolebrutinib is tolerated over a long time. It's for adults with different types of multiple sclerosis (MS) who have already been in earlier tolebrutinib studies.
Relapsing Multiple SclerosisSecondary Progressive Multiple SclerosisProgressive Relapsing Multiple SclerosisSerbia - Active not recruitingPHASE3
A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus
This study is looking into a new treatment called anifrolumab for adults with a skin condition called cutaneous lupus erythematosus (CLE). It aims to see if anifrolumab is effective and safe compared to a dummy treatment.
Cutaneous Lupus ErythematosusSerbia - Active not recruitingPHASE3
A Study of Milvexian Versus Apixaban in Participants With Atrial Fibrillation
This study is comparing two medicines, milvexian and apixaban, for people with an irregular heartbeat called atrial fibrillation. We want to see if milvexian is just as good as apixaban at stopping serious problems like strokes, which can happen with this condition.
Atrial FibrillationSerbia - Enrolling by invitationPHASE3
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
This study looks at the long-term effects and safety of a drug called Ralinepag for people with a lung condition called pulmonary arterial hypertension (PAH). It's for those who have already tried Ralinepag in a previous study.
PAHPulmonary HypertensionPulmonary Arterial HypertensionHypertensionSerbia - Active not recruitingPHASE2
A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)
This study looks at a new oral medicine called paltusotine for people with acromegaly. It checks how safe and effective it is over a long time for those who have already tried it in previous studies. The aim is to see if it continues to help manage the condition.
AcromegalySerbia - Active not recruitingPHASE3
A Study to Evaluate the Long-Term Safety and Efficacy of Upadacitinib (ABT-494) in Participants With Ulcerative Colitis (UC)
This study looks at the long-term safety and effectiveness of a medicine called Upadacitinib for people with ulcerative colitis. It's for those who haven't fully responded to previous treatment or have completed an earlier study.
Ulcerative Colitis (UC)Serbia - Active not recruitingPHASE2
To Assess Efficacy and Safety of Batoclimab in Adult Participants With Active CIDP
This study is testing a new drug called batoclimab for adults with a nerve condition called Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). It aims to see how well it works and if it's safe compared to a dummy drug.
Chronic Inflammatory Demyelinating PolyneuropathySerbia - RecruitingPHASE2, PHASE3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
This study is looking at a new medicine called vericiguat for children and young people aged 29 days to 17 years with heart failure. We want to see if it can improve their heart health compared to a dummy medicine.
Heart FailureLeft Ventricular Systolic DysfunctionSerbia - RecruitingPHASE3
Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis
This study is testing a new treatment, called Descartes-08, for myasthenia gravis. It uses your own cells, changed to fight the disease. We want to see if it's safe and helps people with a specific type of this condition.
Myasthaenia GravisSerbia - RecruitingPHASE3
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
This study is testing a new medication called dapirolizumab pegol (DZP) for people with moderate to severe lupus (SLE). It aims to see if DZP, when added to usual treatments, can safely improve their symptoms over a long time.
Systemic Lupus ErythematosusSerbia - RecruitingPHASE3
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis
This study is testing a new medicine, IMVT-1402, for adults with a condition called myasthenia gravis. The aim is to see if it's safe and helps improve daily life for those with mild to severe symptoms.
Generalized Myasthenia GravisSerbia - Active not recruitingPHASE3
A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
This study is testing a new medicine called lutikizumab for people aged 12 and over with moderate to severe hidradenitis suppurativa (HS). It compares the new medicine to a dummy treatment (placebo) to see if it helps reduce HS symptoms and is safe.
Hidradenitis SuppurativaSerbia - RecruitingPHASE2
Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)
This study is testing a new medicine, tibulizumab, for an illness called systemic sclerosis (scleroderma). We want to see if it helps improve symptoms over 24 weeks, followed by an additional 28 weeks where everyone gets the study drug.
Systemic Sclerosis (SSc)SclerodermaSerbia - Recruiting
SPECTA: Screening Cancer Patients for Efficient Clinical Trial Access
This study, called SPECTA, collects information and samples from cancer patients to help scientists better understand cancer. It aims to improve how we diagnose and treat different types of cancer in the future by looking at many different aspects of the disease.
All Tumor TypesSerbia - Enrolling by invitationPHASE3
A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy
This study looks at a new medicine called efgartigimod for people with certain muscle conditions like myositis. It's for adults who were in a previous study, to see if the medicine is safe and helpful over a long time.
MyositisActive Idiopathic Inflammatory MyopathyDermatomyositisPolymyositisSerbia - Active not recruitingPHASE3
Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus
This study looks at a new tablet treatment, upadacitinib, for adults with moderate to severe lupus. It checks how safe and effective the medicine is and aims to reduce symptoms. Some people will get the active drug, others a dummy pill.
Systemic Lupus ErythematosusSerbia - Recruiting
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry
This study tracks the health of people with Gaucher disease over time, whether or not they are receiving treatment. There's also a sub-study for pregnant women with Gaucher disease to see how their pregnancies and babies' health progress. It helps doctors learn more about the condition.
Gaucher DiseaseCerebroside Lipidosis SyndromeGlucocerebrosidase Deficiency DiseaseGlucosylceramide Beta-Glucosidase Deficiency DiseaseSerbia - Active not recruitingPHASE3
A Study to Compare Safety and Efficacy of High Doses of Eteplirsen in Participants With Duchenne Muscular Dystrophy (DMD) (MIS51ON)
This study is looking at higher doses of a medicine called eteplirsen for boys with Duchenne muscular dystrophy (DMD). It's checking if these higher doses are safe and work better than the usual dose to help manage the condition.
Muscular Dystrophy, DuchenneSerbia - Enrolling by invitation
European TIF2.0 Registry
This study looks at a keyhole procedure called TIF to treat reflux (heartburn and sickness). Doctors want to see how safe and effective it is for people experiencing symptoms like stomach acid coming up and a sore throat, sometimes combined with a small hernia repair.
Gastro -Oesophagal RefluxLaryngo-pharyngeal RefluxSerbia - Active not recruitingPHASE3
A Study to Investigate the Efficacy and Safety of Brepocitinib in Adults With Dermatomyositis
This study is looking into a new medication called brepocitinib for adults with dermatomyositis. Researchers want to see if it's safe and helps improve symptoms compared to a placebo. Participants will receive either the new drug or a dummy pill for a year.
DermatomyositisSerbia